ID   RNP2_THEKO              Reviewed;         120 AA.
AC   Q5JJ62;
DT   30-AUG-2005, integrated into UniProtKB/Swiss-Prot.
DT   15-FEB-2005, sequence version 1.
DT   27-MAR-2024, entry version 91.
DE   RecName: Full=Ribonuclease P protein component 2 {ECO:0000255|HAMAP-Rule:MF_00755};
DE            Short=RNase P component 2 {ECO:0000255|HAMAP-Rule:MF_00755};
DE            EC=3.1.26.5 {ECO:0000255|HAMAP-Rule:MF_00755};
DE   AltName: Full=Pop5 {ECO:0000255|HAMAP-Rule:MF_00755};
GN   Name=rnp2 {ECO:0000255|HAMAP-Rule:MF_00755}; OrderedLocusNames=TK1767;
OS   Thermococcus kodakarensis (strain ATCC BAA-918 / JCM 12380 / KOD1)
OS   (Pyrococcus kodakaraensis (strain KOD1)).
OC   Archaea; Euryarchaeota; Thermococci; Thermococcales; Thermococcaceae;
OC   Thermococcus.
OX   NCBI_TaxID=69014;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC BAA-918 / JCM 12380 / KOD1;
RX   PubMed=15710748; DOI=10.1101/gr.3003105;
RA   Fukui T., Atomi H., Kanai T., Matsumi R., Fujiwara S., Imanaka T.;
RT   "Complete genome sequence of the hyperthermophilic archaeon Thermococcus
RT   kodakaraensis KOD1 and comparison with Pyrococcus genomes.";
RL   Genome Res. 15:352-363(2005).
CC   -!- FUNCTION: Part of ribonuclease P, a protein complex that generates
CC       mature tRNA molecules by cleaving their 5'-ends. {ECO:0000255|HAMAP-
CC       Rule:MF_00755}.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=Endonucleolytic cleavage of RNA, removing 5'-extranucleotides
CC         from tRNA precursor.; EC=3.1.26.5; Evidence={ECO:0000255|HAMAP-
CC         Rule:MF_00755};
CC   -!- SUBUNIT: Consists of a catalytic RNA component and at least 4-5 protein
CC       subunits. {ECO:0000255|HAMAP-Rule:MF_00755}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00755}.
CC   -!- SIMILARITY: Belongs to the eukaryotic/archaeal RNase P protein
CC       component 2 family. {ECO:0000255|HAMAP-Rule:MF_00755}.
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DR   EMBL; AP006878; BAD85956.1; -; Genomic_DNA.
DR   RefSeq; WP_011250718.1; NC_006624.1.
DR   PDB; 3WZ0; X-ray; 2.79 A; A/C=1-120.
DR   PDBsum; 3WZ0; -.
DR   AlphaFoldDB; Q5JJ62; -.
DR   SMR; Q5JJ62; -.
DR   STRING; 69014.TK1767; -.
DR   EnsemblBacteria; BAD85956; BAD85956; TK1767.
DR   GeneID; 78448297; -.
DR   KEGG; tko:TK1767; -.
DR   PATRIC; fig|69014.16.peg.1723; -.
DR   eggNOG; arCOG01365; Archaea.
DR   HOGENOM; CLU_137733_1_0_2; -.
DR   InParanoid; Q5JJ62; -.
DR   OrthoDB; 19261at2157; -.
DR   PhylomeDB; Q5JJ62; -.
DR   Proteomes; UP000000536; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0030677; C:ribonuclease P complex; IEA:UniProtKB-UniRule.
DR   GO; GO:0004526; F:ribonuclease P activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0001682; P:tRNA 5'-leader removal; IEA:UniProtKB-UniRule.
DR   Gene3D; 3.30.70.3250; Ribonuclease P, Pop5 subunit; 1.
DR   HAMAP; MF_00755; RNase_P_2; 1.
DR   InterPro; IPR002759; Pop5/Rpp14/Rnp2-like.
DR   InterPro; IPR038085; Rnp2-like_sf.
DR   InterPro; IPR016434; Rnp2_archaea.
DR   PANTHER; PTHR15441; RIBONUCLEASE P PROTEIN SUBUNIT P14; 1.
DR   PANTHER; PTHR15441:SF2; RIBONUCLEASE P_MRP PROTEIN SUBUNIT POP5; 1.
DR   Pfam; PF01900; RNase_P_Rpp14; 1.
DR   PIRSF; PIRSF004952; RNase_P_2; 1.
DR   SUPFAM; SSF160350; Rnp2-like; 1.
PE   1: Evidence at protein level;
KW   3D-structure; Cytoplasm; Endonuclease; Hydrolase; Nuclease;
KW   Reference proteome; tRNA processing.
FT   CHAIN           1..120
FT                   /note="Ribonuclease P protein component 2"
FT                   /id="PRO_0000140028"
FT   STRAND          16..27
FT                   /evidence="ECO:0007829|PDB:3WZ0"
FT   HELIX           31..45
FT                   /evidence="ECO:0007829|PDB:3WZ0"
FT   HELIX           47..54
FT                   /evidence="ECO:0007829|PDB:3WZ0"
FT   STRAND          57..62
FT                   /evidence="ECO:0007829|PDB:3WZ0"
FT   TURN            63..66
FT                   /evidence="ECO:0007829|PDB:3WZ0"
FT   STRAND          67..73
FT                   /evidence="ECO:0007829|PDB:3WZ0"
FT   HELIX           74..76
FT                   /evidence="ECO:0007829|PDB:3WZ0"
FT   HELIX           77..85
FT                   /evidence="ECO:0007829|PDB:3WZ0"
FT   STRAND          93..105
FT                   /evidence="ECO:0007829|PDB:3WZ0"
FT   HELIX           106..112
FT                   /evidence="ECO:0007829|PDB:3WZ0"
FT   TURN            113..118
FT                   /evidence="ECO:0007829|PDB:3WZ0"
SQ   SEQUENCE   120 AA;  14047 MW;  2E6A1FF49BAC7239 CRC64;
     MREKPKYLPP TLRDKNRYIA FQVIGERPFK KDEIKKAVWE ASLSALGYLG SARAKPWFIK
     FDEKSQTGIV RVDRKHVEEL RFALTMLTEI NGSKVIFRTL GVSGTIKRLK RKFLAEYGWR
//