Q5JJ62 (RNP2_PYRKO) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Ribonuclease P protein component 2
Short name=RNase P component 2
EC=3.1.26.5

Gene names

Name:	rnp2
Ordered Locus Names:	TK1767

Organism

Pyrococcus kodakaraensis (strain ATCC BAA-918 / JCM 12380 / KOD1) (Thermococcus kodakaraensis (strain KOD1)) [Reference proteome] [HAMAP]

Taxonomic identifier

69014 [NCBI]

Taxonomic lineage

cellular organisms › Archaea › Euryarchaeota › Thermococci › Thermococcales › Thermococcaceae › Thermococcus › Thermococcus kodakarensis

Protein attributes

Sequence length	120 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends By similarity. HAMAP-Rule MF_00755
Catalytic activity	Endonucleolytic cleavage of RNA, removing 5'-extranucleotides from tRNA precursor. HAMAP-Rule MF_00755
Subunit structure	Consists of a catalytic RNA component and at least 4 protein subunits Potential.
Sequence similarities	Belongs to the eukaryotic/archaeal RNase P protein component 2 family.

Ontologies

Keywords
Biological process	tRNA processing
Molecular function	Hydrolase
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	tRNA 5'-leader removal Inferred from electronic annotation. Source: HAMAP
Molecular_function	ribonuclease P activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 120	120	Ribonuclease P protein component 2 HAMAP-Rule MF_00755		PRO_0000140028

Sequences

	Sequence		Length	Mass (Da)
	Q5JJ62 [UniParc]. Last modified February 15, 2005. Version 1. Checksum: 2E6A1FF49BAC7239	FASTA	120	14,047
	10 20 30 40 50 60 MREKPKYLPP TLRDKNRYIA FQVIGERPFK KDEIKKAVWE ASLSALGYLG SARAKPWFIK 70 80 90 100 110 120 FDEKSQTGIV RVDRKHVEEL RFALTMLTEI NGSKVIFRTL GVSGTIKRLK RKFLAEYGWR

References

[1]

"Complete genome sequence of the hyperthermophilic archaeon Thermococcus kodakaraensis KOD1 and comparison with Pyrococcus genomes." Fukui T., Atomi H., Kanai T., Matsumi R., Fujiwara S., Imanaka T. Genome Res. 15:352-363(2005) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC BAA-918 / JCM 12380 / KOD1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AP006878 Genomic DNA. Translation: BAD85956.1.
RefSeq	YP_184180.1. NC_006624.1.
3D structure databases
ProteinModelPortal	Q5JJ62.
SMR	Q5JJ62. Positions 4-120.
ModBase	Search...
Protein-protein interaction databases
STRING	69014.TK1767.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	BAD85956; BAD85956; TK1767.
GeneID	3235444.
KEGG	tko:TK1767.
Phylogenomic databases
eggNOG	COG1369.
HOGENOM	HOG000286243.
KO	K03537.
OMA	NPWLIDY.
ProtClustDB	PRK03717.
Family and domain databases
HAMAP	MF_00755. RNase_P_2.
InterPro	IPR002759. RNase_P/MRP_subunit. IPR016434. RNase_P_comp-2. [Graphical view]
Pfam	PF01900. RNase_P_Rpp14. 1 hit. [Graphical view]
PIRSF	PIRSF004952. RNase_P_2. 1 hit.
ProtoNet	Search...

Entry information

Entry name

RNP2_PYRKO

Accession

Primary (citable) accession number: Q5JJ62

Entry history

Integrated into UniProtKB/Swiss-Prot:	August 30, 2005
Last sequence update:	February 15, 2005
Last modified:	May 1, 2013
This is version 45 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program