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Q5JIK2 (PORC_PYRKO) Reviewed, UniProtKB/Swiss-Prot

Last modified December 14, 2011. Version 50. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Pyruvate/ketoisovalerate oxidoreductases common subunit gamma

Including the following 2 domains:

  1. Pyruvate synthase subunit porC
    EC=1.2.7.1
    Alternative name(s):
    Pyruvate oxidoreductase gamma chain
    Short name=POR
    Pyruvic-ferredoxin oxidoreductase subunit gamma
  2. Ketoisovalerate oxidoreductase subunit vorC
    Short name=VOR
    EC=1.2.7.7
    Alternative name(s):
    2-oxoisovalerate ferredoxin reductase subunit gamma
    2-oxoisovalerate oxidoreductase gamma chain
Gene names
Name:porG
Ordered Locus Names:TK1978
OrganismPyrococcus kodakaraensis (strain ATCC BAA-918 / JCM 12380 / KOD1) (Thermococcus kodakaraensis (strain KOD1))
Taxonomic identifier69014 [NCBI]
Taxonomic lineageArchaeaEuryarchaeotaThermococciThermococcalesThermococcaceaeThermococcus

Protein attributes

Sequence length185 AA.
Sequence statusComplete.
Protein existencePredicted

General annotation (Comments)

Catalytic activity

Pyruvate + CoA + 2 oxidized ferredoxin = acetyl-CoA + CO2 + 2 reduced ferredoxin + 2 H+.

3-methyl-2-oxobutanoate + CoA + 2 oxidized ferredoxin = S-(2-methylpropanoyl)-CoA + CO2 + 2 reduced ferredoxin + H+.

Subunit structure

Heterotetramer of one alpha, one beta, one delta and one gamma chain.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 185185Pyruvate/ketoisovalerate oxidoreductases common subunit gamma
PRO_0000099916

Sequences

Sequence LengthMass (Da)Tools
Q5JIK2 [UniParc].

Last modified February 15, 2005. Version 1.
Checksum: 4ACBC76A5E2DD707

FASTA18519,693
        10         20         30         40         50         60 
MIEIRFHGRG GQGAVTAANI LASAAFKEGK YVQAFPFFGV ERRGAPVTAF TRIDDKPIRI 

        70         80         90        100        110        120 
KTQIYEPDVV VVLDPSLLDT VDVTAGLKDG GIVIVNTEKS KEEVLEKLKK KPGKLALVDA 

       130        140        150        160        170        180 
TGIALEILGL PITNTAILGA VAKATGLVKL ESVQEAIKET FSGALGEKNA KAAEEAFNKT 


VVYEL 

« Hide

References

[1]"Complete genome sequence of the hyperthermophilic archaeon Thermococcus kodakaraensis KOD1 and comparison with Pyrococcus genomes."
Fukui T., Atomi H., Kanai T., Matsumi R., Fujiwara S., Imanaka T.
Genome Res. 15:352-363(2005) [PubMed: 15710748] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC BAA-918 / JCM 12380 / KOD1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AP006878 Genomic DNA. Translation: BAD86167.1.
RefSeqYP_184391.1. NC_006624.1.

3D structure databases

ProteinModelPortalQ5JIK2.
ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaEBPYRT00000006451; EBPYRP00000006232; EBPYRG00000006450.
GeneID3235685.
GenomeReviewsGene locus TK1978 in contig AP006878_GR.
KEGGtko:TK1978.
NMPDRfig|69014.3.peg.1827.

Phylogenomic databases

eggNOGarNOG07814.
GeneTreeEBGT00050000022250.
HOGENOMHBG553299.
OMAIKVYSQI.
PhylomeDBQ5JIK2.
ProtClustDBPRK14029.

Enzyme and pathway databases

BioCycTKOD69014:TK1978-MONOMER.

Family and domain databases

InterProIPR011894. PorC_KorC.
IPR019752. Pyrv/ketoisovalerate_OxRed_cat.
IPR002869. Pyrv_flavodox_OxRed_cen.
[Graphical view]
Gene3DG3DSA:3.40.920.10. Pyrv_Fd/Flavodoxin_OxRdtase. 1 hit.
KOK00189.
PfamPF01558. POR. 1 hit.
[Graphical view]
SUPFAMSSF53323. Pyrv_Fd/Flavodoxin_OxRdtase. 1 hit.
TIGRFAMsTIGR02175. PorC_KorC. 1 hit.
ProtoNetSearch...

Entry information

Entry namePORC_PYRKO
AccessionPrimary (citable) accession number: Q5JIK2
Entry history
Integrated into UniProtKB/Swiss-Prot: October 25, 2005
Last sequence update: February 15, 2005
Last modified: December 14, 2011
This is version 50 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program