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Reviewed, UniProtKB/Swiss-Prot Q5JIK2 (PORC_PYRKO)

Last modified June 15, 2010. Version 37. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data | Customize display text xml rdf/xml gff fasta
Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information
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Names and originHide

Protein namesRecommended name:
Pyruvate/ketoisovalerate oxidoreductases common subunit gamma

Including the following 2 domains:

  1. Pyruvate synthase subunit porC
    EC=1.2.7.1
    Alternative name(s):
    Pyruvate oxidoreductase gamma chain
    Short name=POR
    Pyruvic-ferredoxin oxidoreductase subunit gamma
  2. Ketoisovalerate oxidoreductase subunit vorC
    Short name=VOR
    EC=1.2.7.7
    Alternative name(s):
    2-oxoisovalerate oxidoreductase gamma chain
    2-oxoisovalerate ferredoxin reductase subunit gamma
Gene names
Name:porG
Ordered Locus Names:TK1978
OrganismPyrococcus kodakaraensis (Thermococcus kodakaraensis) [Complete proteome] [HAMAP]
Taxonomic identifier311400 [NCBI]
Taxonomic lineageArchaea › Euryarchaeota › Thermococci › Thermococcales › Thermococcaceae › Thermococcus
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Protein attributesHide

Sequence length185 AA.
Sequence statusComplete.
Protein existencePredicted.
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General annotation (Comments)Hide

Catalytic activity

Pyruvate + CoA + 2 oxidized ferredoxin = acetyl-CoA + CO2 + 2 reduced ferredoxin + 2 H+.

3-methyl-2-oxobutanoate + CoA + 2 oxidized ferredoxin = S-(2-methylpropanoyl)-CoA + CO2 + 2 reduced ferredoxin + H+.

Subunit structure

Heterotetramer of one alpha, one beta, one delta and one gamma chain.

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Sequence annotation (Features)Hide

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 185185Pyruvate/ketoisovalerate oxidoreductases common subunit gamma
PRO_0000099916
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SequencesHide

Sequence LengthMass (Da)Tools
Q5JIK2-1 [UniParc].

Last modified February 15, 2005. Version 1.
Checksum: 4ACBC76A5E2DD707

FASTA18519,693
        10         20         30         40         50         60 
MIEIRFHGRG GQGAVTAANI LASAAFKEGK YVQAFPFFGV ERRGAPVTAF TRIDDKPIRI 

        70         80         90        100        110        120 
KTQIYEPDVV VVLDPSLLDT VDVTAGLKDG GIVIVNTEKS KEEVLEKLKK KPGKLALVDA 

       130        140        150        160        170        180 
TGIALEILGL PITNTAILGA VAKATGLVKL ESVQEAIKET FSGALGEKNA KAAEEAFNKT 


VVYEL

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ReferencesHide

[1]"Complete genome sequence of the hyperthermophilic archaeon Thermococcus kodakaraensis KOD1 and comparison with Pyrococcus genomes."
Fukui T., Atomi H., Kanai T., Matsumi R., Fujiwara S., Imanaka T.
Genome Res. 15:352-363(2005) [PubMed: 15710748] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: KOD1.
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Cross-referencesHide

Sequence databases

EMBL
GenBank
DDBJ		AP006878 Genomic DNA. Translation: BAD86167.1.
RefSeqYP_184391.1.

3D structure databases

SMRQ5JIK2. Positions 1-179.
ModBaseSearch...

Protein-protein interaction databases

STRINGQ5JIK2.

Genome annotation databases

EnsemblBacteriaEBPYRT00000006451; EBPYRP00000006232; EBPYRG00000006450.
GeneID3235685.
GenomeReviewsGene locus TK1978 in contig AP006878_GR.
KEGGtko:TK1978.
NMPDRfig|69014.3.peg.1827.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGarNOG07814.
HOGENOMHBG553299.
OMAIKVYSQI.
ProtClustDBPRK14029.

Enzyme and pathway databases

BioCycTKOD69014:TK1978-MONOMER.
BRENDA1.2.7.1. 192130.
1.2.7.7. 192130.

Family and domain databases

InterProIPR011894. PorC_KorC.
IPR019752. Pyrv/ketoisovalerate_OxRed_cat.
IPR002869. Pyrv_flavodox_OxRed_cen.
[Graphical view]
Gene3DG3DSA:3.40.920.10. Pyrv_Fd/Flavodoxin_OxRdtase. 1 hit.
PfamPF01558. POR. 1 hit.
[Graphical view]
SUPFAMSSF53323. Pyrv_Fd/Flavodoxin_OxRdtase. 1 hit.
TIGRFAMsTIGR02175. PorC_KorC. 1 hit.
ProtoNetSearch...
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Entry informationHide

Entry namePORC_PYRKO
AccessionPrimary (citable) accession number: Q5JIK2
Entry history
Integrated into UniProtKB/Swiss-Prot: October 25, 2005
Last sequence update: February 15, 2005
Last modified: June 15, 2010
This is version 37 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation projectHAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)
Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information