Reviewed, UniProtKB/Swiss-Prot Q5JIK2 (PORC_PYRKO)

Names and origin

Protein names

Recommended name:
    Pyruvate/ketoisovalerate oxidoreductases common subunit gamma
Including the following 2 domains:
    1- Recommended name:
            Pyruvate synthase subunit porC
              EC=1.2.7.1
        Alternative name(s):
            Pyruvate oxidoreductase gamma chain
              Short name=POR
            Pyruvic-ferredoxin oxidoreductase subunit gamma
    2- Recommended name:
            Ketoisovalerate oxidoreductase subunit vorC
                Short name=VOR
              EC=1.2.7.7
        Alternative name(s):
            2-oxoisovalerate oxidoreductase gamma chain
            2-oxoisovalerate ferredoxin reductase subunit gamma

Gene names

Name:	porG
Ordered Locus Names:	TK1978

Organism

Pyrococcus kodakaraensis (Thermococcus kodakaraensis) [Complete proteome] [HAMAP]

Taxonomic identifier

69014 [NCBI]

Taxonomic lineage

Archaea › Euryarchaeota › Thermococci › Thermococcales › Thermococcaceae › Thermococcus

Protein attributes

Sequence length	185 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Predicted.

General annotation (Comments)

Catalytic activity	Pyruvate + CoA + 2 oxidized ferredoxin = acetyl-CoA + CO(2) + 2 reduced ferredoxin + 2 H(+). 3-methyl-2-oxobutanoate + CoA + 2 oxidized ferredoxin = S-(2-methylpropanoyl)-CoA + CO(2) + 2 reduced ferredoxin + H(+).
Subunit structure	Heterotetramer of one alpha, one beta, one delta and one gamma chain.

Ontologies

Keywords
Molecular function	Oxidoreductase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	oxidation reduction Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	3-methyl-2-oxobutanoate dehydrogenase (ferredoxin) activity Inferred from electronic annotation. Source: EC electron carrier activity Inferred from electronic annotation. Source: InterPro pyruvate synthase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 185	185	Pyruvate/ketoisovalerate oxidoreductases common subunit gamma		PRO_0000099916

Sequences

	Sequence		Length	Mass (Da)
	Q5JIK2-1 [UniParc]. Last modified February 15, 2005. Version 1. Checksum: 4ACBC76A5E2DD707	FASTA	185	19,693
	10 20 30 40 50 60 MIEIRFHGRG GQGAVTAANI LASAAFKEGK YVQAFPFFGV ERRGAPVTAF TRIDDKPIRI 70 80 90 100 110 120 KTQIYEPDVV VVLDPSLLDT VDVTAGLKDG GIVIVNTEKS KEEVLEKLKK KPGKLALVDA 130 140 150 160 170 180 TGIALEILGL PITNTAILGA VAKATGLVKL ESVQEAIKET FSGALGEKNA KAAEEAFNKT VVYEL

References

[1]

"Complete genome sequence of the hyperthermophilic archaeon Thermococcus kodakaraensis KOD1 and comparison with Pyrococcus genomes." Fukui T., Atomi H., Kanai T., Matsumi R., Fujiwara S., Imanaka T. Genome Res. 15:352-363(2005) [PubMed: 15710748] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: KOD1.

Cross-references

Sequence databases
EMBLGenBankDDBJ	AP006878 Genomic DNA. Translation: BAD86167.1.
RefSeq	YP_184391.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	3235685.
GenomeReviews	Gene locus TK1978 in contig AP006878_GR.
KEGG	tko:TK1978.
NMPDR	fig|69014.3.peg.1827.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	Q5JIK2.
Enzyme and pathway databases
BioCyc	TKOD69014:TK1978-MON.
Family and domain databases
InterPro	IPR011894. PorC_KorC. IPR002869. Pyrv_Fd/Flavodoxin_OxRdtase. [Graphical view]
Gene3D	G3DSA:3.40.920.10. Pyrv_Fd/Flavodoxin_OxRdtase. 1 hit.
Pfam	PF01558. POR. 1 hit. [Graphical view]
TIGRFAMs	TIGR02175. PorC_KorC. 1 hit.
ProtoNet	Search...

Entry information

Entry name

PORC_PYRKO

Accession

Primary (citable) accession number: Q5JIK2

Entry history

Integrated into UniProtKB/Swiss-Prot:	October 25, 2005
Last sequence update:	February 15, 2005
Last modified:	November 25, 2008
This is version 26 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)