Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Prefoldin subunit alpha 1

Gene

pfdA1

Organism
Thermococcus kodakarensis (strain ATCC BAA-918 / JCM 12380 / KOD1) (Pyrococcus kodakaraensis (strain KOD1))
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding.UniRule annotation

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Chaperone

Enzyme and pathway databases

BioCyciTKOD69014:GH72-1018-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Prefoldin subunit alpha 1UniRule annotation
Alternative name(s):
GimC subunit alpha 1UniRule annotation
Gene namesi
Name:pfdA1UniRule annotation
Ordered Locus Names:TK1005
OrganismiThermococcus kodakarensis (strain ATCC BAA-918 / JCM 12380 / KOD1) (Pyrococcus kodakaraensis (strain KOD1))
Taxonomic identifieri69014 [NCBI]
Taxonomic lineageiArchaeaEuryarchaeotaThermococciThermococcalesThermococcaceaeThermococcus
Proteomesi
  • UP000000536 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 146146Prefoldin subunit alpha 1PRO_0000153685Add
BLAST

Interactioni

Subunit structurei

Heterohexamer of two alpha and four beta subunits.UniRule annotation

Protein-protein interaction databases

STRINGi69014.TK1005.

Structurei

3D structure databases

ProteinModelPortaliQ5JIE3.
SMRiQ5JIE3. Positions 1-146.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the prefoldin subunit alpha family.Curated

Phylogenomic databases

eggNOGiarCOG01341. Archaea.
COG1730. LUCA.
HOGENOMiHOG000055160.
InParanoidiQ5JIE3.
KOiK04797.
OMAiRNEFQAV.

Family and domain databases

Gene3Di1.10.287.370. 1 hit.
HAMAPiMF_00308. PfdA.
InterProiIPR011599. PFD_alpha_archaea.
IPR009053. Prefoldin.
IPR004127. Prefoldin_subunit_alpha.
[Graphical view]
PfamiPF02996. Prefoldin. 1 hit.
[Graphical view]
SUPFAMiSSF46579. SSF46579. 1 hit.
TIGRFAMsiTIGR00293. TIGR00293. 1 hit.

Sequencei

Sequence statusi: Complete.

Q5JIE3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAEDTKKLEE LAYQYQLLQA QAQLLAQNLE LLTLGRNEFQ AVKETLEGLK
60 70 80 90 100
NEEGEFEILV PIGAGSFLKG KIVDAKNAIV SVGAGYAVQK SLDDSIEYLE
110 120 130 140
KRIKEYEEAI AKTQEALKKL EAQLGELARQ AQEIQQKQAM GFSVKK
Length:146
Mass (Da):16,275
Last modified:February 15, 2005 - v1
Checksum:i19DCAD3BA7F7B02C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP006878 Genomic DNA. Translation: BAD85194.1.
RefSeqiWP_011249956.1. NC_006624.1.

Genome annotation databases

EnsemblBacteriaiBAD85194; BAD85194; TK1005.
GeneIDi3234318.
KEGGitko:TK1005.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP006878 Genomic DNA. Translation: BAD85194.1.
RefSeqiWP_011249956.1. NC_006624.1.

3D structure databases

ProteinModelPortaliQ5JIE3.
SMRiQ5JIE3. Positions 1-146.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi69014.TK1005.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiBAD85194; BAD85194; TK1005.
GeneIDi3234318.
KEGGitko:TK1005.

Phylogenomic databases

eggNOGiarCOG01341. Archaea.
COG1730. LUCA.
HOGENOMiHOG000055160.
InParanoidiQ5JIE3.
KOiK04797.
OMAiRNEFQAV.

Enzyme and pathway databases

BioCyciTKOD69014:GH72-1018-MONOMER.

Family and domain databases

Gene3Di1.10.287.370. 1 hit.
HAMAPiMF_00308. PfdA.
InterProiIPR011599. PFD_alpha_archaea.
IPR009053. Prefoldin.
IPR004127. Prefoldin_subunit_alpha.
[Graphical view]
PfamiPF02996. Prefoldin. 1 hit.
[Graphical view]
SUPFAMiSSF46579. SSF46579. 1 hit.
TIGRFAMsiTIGR00293. TIGR00293. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. "Complete genome sequence of the hyperthermophilic archaeon Thermococcus kodakaraensis KOD1 and comparison with Pyrococcus genomes."
    Fukui T., Atomi H., Kanai T., Matsumi R., Fujiwara S., Imanaka T.
    Genome Res. 15:352-363(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC BAA-918 / JCM 12380 / KOD1.

Entry informationi

Entry nameiPFDA1_THEKO
AccessioniPrimary (citable) accession number: Q5JIE3
Entry historyi
Integrated into UniProtKB/Swiss-Prot: August 30, 2005
Last sequence update: February 15, 2005
Last modified: November 11, 2015
This is version 70 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.