Q5JI21 (APGM_PYRKO) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
2,3-bisphosphoglycerate-independent phosphoglycerate mutase
Short name=BPG-independent PGAM
Short name=Phosphoglyceromutase
Short name=aPGAM
EC=5.4.2.1

Gene names

Name:	apgM
Ordered Locus Names:	TK0866

Organism

Pyrococcus kodakaraensis (strain ATCC BAA-918 / JCM 12380 / KOD1) (Thermococcus kodakaraensis (strain KOD1))

Taxonomic identifier

69014 [NCBI]

Taxonomic lineage

Archaea › Euryarchaeota › Thermococci › Thermococcales › Thermococcaceae › Thermococcus

Protein attributes

Sequence length	411 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate By similarity. HAMAP MF_01402_A
Catalytic activity	2-phospho-D-glycerate = 3-phospho-D-glycerate. HAMAP MF_01402_A
Pathway	Carbohydrate degradation; glycolysis; pyruvate from D-glyceraldehyde 3-phosphate: step 3/5. HAMAP MF_01402_A
Sequence similarities	Belongs to the BPG-independent phosphoglycerate mutase family. A-PGAM subfamily.

Ontologies

Keywords
Biological process	Glycolysis
Molecular function	Isomerase
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological process	glycolysis Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	metal ion binding Inferred from electronic annotation. Source: InterPro phosphoglycerate mutase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 411	411	2,3-bisphosphoglycerate-independent phosphoglycerate mutase HAMAP MF_01402_A		PRO_0000138146

Sequences

	Sequence		Length	Mass (Da)
	Q5JI21 [UniParc]. Last modified February 15, 2005. Version 1. Checksum: B5DCB13B6D69B419	FASTA	411	45,379
	10 20 30 40 50 60 MKKRKGLLII LDGLGDRPIK EFGGKTPLEY ANTPNMDRLA KMGILGQQDP IKPGQPAGSD 70 80 90 100 110 120 TAHLSIFGYD PYKVYRGRGF LEALGVGLDL NEDDLAFRVN FATIENGIIT DRRAGRISTE 130 140 150 160 170 180 EAHELAKAVQ ENVKLPVDFI FVGATGHRAV LVLRGMAKGY RVGENDPHEA GKPPQEFTWE 190 200 210 220 230 240 DEESKKVAEI LEEFVQKAHE VLDKHPINEK RRKEGKPPAN YLLIRGAGTY PDIPMKFTEQ 250 260 270 280 290 300 WKVKAGAVIA VSLVKGVARA IGFDVYTPEG ATGEYNTDVM AKAKKTVELL KDYDFVFLHF 310 320 330 340 350 360 KPTDAAGHDN NPKLKAEMIE KADRMIGYIL EHIDLEDVVI AITGDHSTPC EVMNHSGDPV 370 380 390 400 410 PLLIAGGGVR PDHTESFGER ECMRGGIGRI KGHDIVPIMM DLMNRSEKFG A

References

[1]

"Complete genome sequence of the hyperthermophilic archaeon Thermococcus kodakaraensis KOD1 and comparison with Pyrococcus genomes." Fukui T., Atomi H., Kanai T., Matsumi R., Fujiwara S., Imanaka T. Genome Res. 15:352-363(2005) [PubMed: 15710748] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC BAA-918 / JCM 12380 / KOD1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AP006878 Genomic DNA. Translation: BAD85055.1.
RefSeq	YP_183279.1. NC_006624.1.
3D structure databases
ProteinModelPortal	Q5JI21.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	EBPYRT00000006299; EBPYRP00000006080; EBPYRG00000006298.
GeneID	3235940.
GenomeReviews	Gene locus TK0866 in contig AP006878_GR.
KEGG	tko:TK0866.
NMPDR	fig|69014.3.peg.1335.
Phylogenomic databases
eggNOG	arNOG04733.
GeneTree	EBGT00050000023120.
HOGENOM	HBG463247.
OMA	DIAFRCN.
PhylomeDB	Q5JI21.
ProtClustDB	PRK04024.
Enzyme and pathway databases
BioCyc	TKOD69014:TK0866-MONOMER.
Family and domain databases
HAMAP	MF_01402_A. ApgM_A. [Tree]
InterPro	IPR017849. Alkaline_Pase-like_a/b/a. IPR017850. Alkaline_phosphatase_core. IPR023665. ApgAM. IPR004456. BisP-indep_Pglycerate_Mutase. IPR006124. Metalloenzyme. [Graphical view]
Gene3D	G3DSA:3.40.720.10. Alk_phosphtse. 2 hits.
KO	K15635.
Pfam	PF01676. Metalloenzyme. 1 hit. PF10143. PhosphMutase. 1 hit. [Graphical view]
PIRSF	PIRSF006392. IPGAM_arch. 1 hit.
SUPFAM	SSF53649. Alkaline_phosphatase_core. 1 hit.
TIGRFAMs	TIGR00306. ApgM. 1 hit.
ProtoNet	Search...

Entry information

Entry name

APGM_PYRKO

Accession

Primary (citable) accession number: Q5JI21

Entry history

Integrated into UniProtKB/Swiss-Prot:	March 29, 2005
Last sequence update:	February 15, 2005
Last modified:	January 25, 2012
This is version 47 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program