ID   Q5JHH6_THEKO            Unreviewed;       769 AA.
AC   Q5JHH6;
DT   15-FEB-2005, integrated into UniProtKB/TrEMBL.
DT   15-FEB-2005, sequence version 1.
DT   27-MAR-2024, entry version 103.
DE   SubName: Full=Methyl-accepting chemotaxis protein {ECO:0000313|EMBL:BAD86336.1};
GN   OrderedLocusNames=TK2147 {ECO:0000313|EMBL:BAD86336.1};
OS   Thermococcus kodakarensis (strain ATCC BAA-918 / JCM 12380 / KOD1)
OS   (Pyrococcus kodakaraensis (strain KOD1)).
OC   Archaea; Euryarchaeota; Thermococci; Thermococcales; Thermococcaceae;
OC   Thermococcus.
OX   NCBI_TaxID=69014 {ECO:0000313|EMBL:BAD86336.1, ECO:0000313|Proteomes:UP000000536};
RN   [1] {ECO:0000313|EMBL:BAD86336.1, ECO:0000313|Proteomes:UP000000536}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC BAA-918 / JCM 12380 / KOD1
RC   {ECO:0000313|Proteomes:UP000000536};
RX   PubMed=15710748; DOI=10.1101/gr.3003105;
RA   Fukui T., Atomi H., Kanai T., Matsumi R., Fujiwara S., Imanaka T.;
RT   "Complete genome sequence of the hyperthermophilic archaeon Thermococcus
RT   kodakaraensis KOD1 and comparison with Pyrococcus genomes.";
RL   Genome Res. 15:352-363(2005).
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- SIMILARITY: Belongs to the methyl-accepting chemotaxis (MCP) protein
CC       family. {ECO:0000256|ARBA:ARBA00029447}.
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DR   EMBL; AP006878; BAD86336.1; -; Genomic_DNA.
DR   RefSeq; WP_011251097.1; NC_006624.1.
DR   AlphaFoldDB; Q5JHH6; -.
DR   STRING; 69014.TK2147; -.
DR   EnsemblBacteria; BAD86336; BAD86336; TK2147.
DR   GeneID; 78448684; -.
DR   KEGG; tko:TK2147; -.
DR   PATRIC; fig|69014.16.peg.2103; -.
DR   eggNOG; arCOG02320; Archaea.
DR   eggNOG; arCOG02362; Archaea.
DR   HOGENOM; CLU_000445_107_19_2; -.
DR   InParanoid; Q5JHH6; -.
DR   OrthoDB; 342253at2157; -.
DR   PhylomeDB; Q5JHH6; -.
DR   Proteomes; UP000000536; Chromosome.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR   GO; GO:0004888; F:transmembrane signaling receptor activity; IEA:InterPro.
DR   GO; GO:0006935; P:chemotaxis; IEA:UniProtKB-KW.
DR   GO; GO:0007165; P:signal transduction; IEA:UniProtKB-KW.
DR   CDD; cd06225; HAMP; 1.
DR   CDD; cd11386; MCP_signal; 1.
DR   CDD; cd12913; PDC1_MCP_like; 1.
DR   CDD; cd12912; PDC2_MCP_like; 1.
DR   Gene3D; 6.10.340.10; -; 1.
DR   Gene3D; 1.10.287.950; Methyl-accepting chemotaxis protein; 1.
DR   Gene3D; 3.30.450.20; PAS domain; 2.
DR   InterPro; IPR004090; Chemotax_Me-accpt_rcpt.
DR   InterPro; IPR033479; dCache_1.
DR   InterPro; IPR003660; HAMP_dom.
DR   InterPro; IPR004089; MCPsignal_dom.
DR   InterPro; IPR029151; Sensor-like_sf.
DR   PANTHER; PTHR32089:SF92; LYSOZYME-LIKE PROTEIN-RELATED; 1.
DR   PANTHER; PTHR32089; METHYL-ACCEPTING CHEMOTAXIS PROTEIN MCPB; 1.
DR   Pfam; PF02743; dCache_1; 1.
DR   Pfam; PF00672; HAMP; 1.
DR   Pfam; PF00015; MCPsignal; 1.
DR   PRINTS; PR00260; CHEMTRNSDUCR.
DR   SMART; SM00304; HAMP; 3.
DR   SMART; SM00283; MA; 1.
DR   SUPFAM; SSF58104; Methyl-accepting chemotaxis protein (MCP) signaling domain; 1.
DR   SUPFAM; SSF103190; Sensory domain-like; 1.
DR   PROSITE; PS50111; CHEMOTAXIS_TRANSDUC_2; 1.
DR   PROSITE; PS50885; HAMP; 2.
PE   3: Inferred from homology;
KW   Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW   Chemotaxis {ECO:0000256|ARBA:ARBA00022500};
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136};
KW   Reference proteome {ECO:0000313|Proteomes:UP000000536};
KW   Transducer {ECO:0000256|ARBA:ARBA00023224, ECO:0000256|PROSITE-
KW   ProRule:PRU00284}; Transmembrane {ECO:0000256|ARBA:ARBA00022692};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989}.
FT   DOMAIN          361..419
FT                   /note="HAMP"
FT                   /evidence="ECO:0000259|PROSITE:PS50885"
FT   DOMAIN          421..464
FT                   /note="HAMP"
FT                   /evidence="ECO:0000259|PROSITE:PS50885"
FT   DOMAIN          483..740
FT                   /note="Methyl-accepting transducer"
FT                   /evidence="ECO:0000259|PROSITE:PS50111"
FT   COILED          480..511
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          624..658
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          698..763
FT                   /evidence="ECO:0000256|SAM:Coils"
SQ   SEQUENCE   769 AA;  84620 MW;  EE2BB5234D5FDEBD CRC64;
     MQFRKKIAVI VIAAVLVTLL IGSATVGYAT LKMRDNIQKT LDVQLNEVLP KEMEKSVQEP
     ITEEAGTITV SAAELGARLF DDYFDKMRMM GDVAVQDVLE AYSKYDESDP QFKAFLLKRF
     EMVKNLDPNV AYVYFGSTTG GMYMWPDEPL PEGYDPRVRP WYKEAVDKNG PVWTEPYKDA
     STGKWIVTFS EPVYINGEFV GVIGVDVFVS TLIDQAKQIK IGQTGYIAIL NKDGTIIVHP
     DESLVQKLNI HDDPNLASLA GELDKNKETG WIRYTFKGVD KIGGYKRMKT TGWIVLATVP
     INELTDPMMN AIDSSLKANT EKVASEINSE VNSGIKTSLL GSVFAAVFGL IVLGIAYRTL
     NTTLKPLEQL RDVAQALADG RLSEVREKLR GIQYLEDDEI GALIKAFESV GKDLVGALDT
     IASKLERLAE GDLSNGLSVE AKGELREVLE DLRDTTHRLK GLIGEIVNVT NELDKRANVL
     AQVANDVTEA INQVNEAVQQ VSIEAQRQQE NINEITEGMR LVADMSEESV RAMEEFEGAV
     NEVVHIAEEG RQKGEVSAQQ IQSIQEMMGN IEAAVNRVNE MSRSIEEITN VITGIAEQTN
     LLALNAAIEA ARAGEAGRGF AVVAQEIRNL AEESKKAADN IKEIINRMTE EIRDAVNATQ
     RGVSVVSESS ETLRETTEYL TNIAELISDT GARLGHVKEQ ILRTQEEVDK ALKALENLAA
     SAEETTASAE EVSSAVEEQT AAIEELQRAA TDLKAIVEKL RDIIGKFKL
//