Q5JH47 (RNP3_PYRKO) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Ribonuclease P protein component 3
Short name=RNase P component 3
EC=3.1.26.5

Gene names

Name:	rnp3
Ordered Locus Names:	TK1450

Organism

Pyrococcus kodakaraensis (strain ATCC BAA-918 / JCM 12380 / KOD1) (Thermococcus kodakaraensis (strain KOD1))

Taxonomic identifier

69014 [NCBI]

Taxonomic lineage

Archaea › Euryarchaeota › Thermococci › Thermococcales › Thermococcaceae › Thermococcus

Protein attributes

Sequence length	220 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends By similarity. HAMAP MF_00756
Catalytic activity	Endonucleolytic cleavage of RNA, removing 5'-extranucleotides from tRNA precursor. HAMAP MF_00756
Subunit structure	Consists of a catalytic RNA component and at least 4 protein subunits Potential.
Sequence similarities	Belongs to the eukaryotic/archaeal RNase P protein component 3 family.

Ontologies

Keywords
Biological process	tRNA processing
Molecular function	Hydrolase
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological process	tRNA 5'-leader removal Inferred from electronic annotation. Source: InterPro
Molecular function	ribonuclease P activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 220	220	Ribonuclease P protein component 3 HAMAP MF_00756		PRO_0000140047

Sequences

	Sequence		Length	Mass (Da)
	Q5JH47 [UniParc]. Last modified February 15, 2005. Version 1. Checksum: 02EA82685C7B3EE0	FASTA	220	25,270
	10 20 30 40 50 60 MSEEEVSFSR DYFVEMDVRD EEAHELASDW FDEVVFTKKL VLEDPPDWGS LKEELKELRG 70 80 90 100 110 120 KYGKVALLLV TRKPSLIREV KSRNLKALLY VQGGDMRINR MAIESGVDAL ISPWFGRKDP 130 140 150 160 170 180 GFDHTLAGMA ARRGVAIGFS LSPLLNANPY GRAQILRFMM KTWQLVKKYR VPRFITSSAE 190 200 210 220 SRWEVRGPRD LMSLGINIGM EIPEARASLN FYPRTIVWKL

References

[1]

"Complete genome sequence of the hyperthermophilic archaeon Thermococcus kodakaraensis KOD1 and comparison with Pyrococcus genomes." Fukui T., Atomi H., Kanai T., Matsumi R., Fujiwara S., Imanaka T. Genome Res. 15:352-363(2005) [PubMed: 15710748] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC BAA-918 / JCM 12380 / KOD1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AP006878 Genomic DNA. Translation: BAD85639.1.
RefSeq	YP_183863.1. NC_006624.1.
3D structure databases
ProteinModelPortal	Q5JH47.
SMR	Q5JH47. Positions 12-217.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	EBPYRT00000006284; EBPYRP00000006065; EBPYRG00000006283.
GeneID	3235810.
GenomeReviews	Gene locus TK1450 in contig AP006878_GR.
KEGG	tko:TK1450.
NMPDR	fig|69014.3.peg.1379.
Phylogenomic databases
eggNOG	arNOG09152.
GeneTree	EBGT00050000022696.
HOGENOM	HBG645643.
OMA	WFDEVVF.
ProtClustDB	PRK03892.
Enzyme and pathway databases
BioCyc	TKOD69014:TK1450-MONOMER.
Family and domain databases
HAMAP	MF_00756. RNase_P_3. [Tree]
InterPro	IPR016195. Pol/histidinol_Pase-like. IPR023539. RNase_P_comp-3. IPR002738. RNase_P_p30. [Graphical view]
KO	K03539.
Pfam	PF01876. RNase_P_p30. 1 hit. [Graphical view]
SUPFAM	SSF89550. PHP-like. 1 hit.
ProtoNet	Search...

Entry information

Entry name

RNP3_PYRKO

Accession

Primary (citable) accession number: Q5JH47

Entry history

Integrated into UniProtKB/Swiss-Prot:	August 30, 2005
Last sequence update:	February 15, 2005
Last modified:	November 16, 2011
This is version 42 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program