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Protein

Ribonuclease P protein component 3

Gene

rnp3

Organism
Thermococcus kodakarensis (strain ATCC BAA-918 / JCM 12380 / KOD1) (Pyrococcus kodakaraensis (strain KOD1))
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends.UniRule annotation

Catalytic activityi

Endonucleolytic cleavage of RNA, removing 5'-extranucleotides from tRNA precursor.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Endonuclease, Hydrolase, Nuclease

Keywords - Biological processi

tRNA processing

Names & Taxonomyi

Protein namesi
Recommended name:
Ribonuclease P protein component 3UniRule annotation (EC:3.1.26.5UniRule annotation)
Short name:
RNase P component 3UniRule annotation
Alternative name(s):
Rpp30UniRule annotation
Gene namesi
Name:rnp3UniRule annotation
Ordered Locus Names:TK1450
OrganismiThermococcus kodakarensis (strain ATCC BAA-918 / JCM 12380 / KOD1) (Pyrococcus kodakaraensis (strain KOD1))
Taxonomic identifieri69014 [NCBI]
Taxonomic lineageiArchaeaEuryarchaeotaThermococciThermococcalesThermococcaceaeThermococcus
Proteomesi
  • UP000000536 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001400471 – 220Ribonuclease P protein component 3Add BLAST220

Interactioni

Subunit structurei

Consists of a catalytic RNA component and at least 4-5 protein subunits.UniRule annotation

Protein-protein interaction databases

STRINGi69014.TK1450.

Structurei

Secondary structure

1220
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details
Feature keyPosition(s)DescriptionActionsGraphical viewLength
Beta strandi14 – 18Combined sources5
Helixi21 – 30Combined sources10
Beta strandi32 – 41Combined sources10
Helixi48 – 62Combined sources15
Beta strandi63 – 70Combined sources8
Helixi74 – 83Combined sources10
Beta strandi86 – 92Combined sources7
Helixi96 – 104Combined sources9
Beta strandi108 – 111Combined sources4
Turni113 – 116Combined sources4
Beta strandi117 – 119Combined sources3
Helixi124 – 133Combined sources10
Beta strandi136 – 141Combined sources6
Helixi142 – 145Combined sources4
Helixi149 – 168Combined sources20
Beta strandi173 – 176Combined sources4
Beta strandi179 – 181Combined sources3
Helixi182 – 184Combined sources3
Helixi188 – 198Combined sources11
Helixi202 – 209Combined sources8
Helixi211 – 217Combined sources7

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
3WYZX-ray2.21A1-220[»]
3WZ0X-ray2.79E/F1-220[»]
ProteinModelPortaliQ5JH47.
SMRiQ5JH47.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the eukaryotic/archaeal RNase P protein component 3 family.UniRule annotation

Phylogenomic databases

eggNOGiarCOG00307. Archaea.
COG1603. LUCA.
HOGENOMiHOG000073988.
InParanoidiQ5JH47.
KOiK03539.
OMAiWFDEVVF.

Family and domain databases

HAMAPiMF_00756. RNase_P_3. 1 hit.
InterProiIPR016195. Pol/histidinol_Pase-like.
IPR023539. RNase_P_comp-3_arc.
IPR002738. RNase_P_p30.
[Graphical view]
PANTHERiPTHR13031. PTHR13031. 1 hit.
PfamiPF01876. RNase_P_p30. 1 hit.
[Graphical view]
SUPFAMiSSF89550. SSF89550. 1 hit.

Sequencei

Sequence statusi: Complete.

Q5JH47-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSEEEVSFSR DYFVEMDVRD EEAHELASDW FDEVVFTKKL VLEDPPDWGS
60 70 80 90 100
LKEELKELRG KYGKVALLLV TRKPSLIREV KSRNLKALLY VQGGDMRINR
110 120 130 140 150
MAIESGVDAL ISPWFGRKDP GFDHTLAGMA ARRGVAIGFS LSPLLNANPY
160 170 180 190 200
GRAQILRFMM KTWQLVKKYR VPRFITSSAE SRWEVRGPRD LMSLGINIGM
210 220
EIPEARASLN FYPRTIVWKL
Length:220
Mass (Da):25,270
Last modified:February 15, 2005 - v1
Checksum:i02EA82685C7B3EE0
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP006878 Genomic DNA. Translation: BAD85639.1.
RefSeqiWP_011250401.1. NC_006624.1.

Genome annotation databases

EnsemblBacteriaiBAD85639; BAD85639; TK1450.
GeneIDi3235810.
KEGGitko:TK1450.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP006878 Genomic DNA. Translation: BAD85639.1.
RefSeqiWP_011250401.1. NC_006624.1.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
3WYZX-ray2.21A1-220[»]
3WZ0X-ray2.79E/F1-220[»]
ProteinModelPortaliQ5JH47.
SMRiQ5JH47.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi69014.TK1450.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiBAD85639; BAD85639; TK1450.
GeneIDi3235810.
KEGGitko:TK1450.

Phylogenomic databases

eggNOGiarCOG00307. Archaea.
COG1603. LUCA.
HOGENOMiHOG000073988.
InParanoidiQ5JH47.
KOiK03539.
OMAiWFDEVVF.

Family and domain databases

HAMAPiMF_00756. RNase_P_3. 1 hit.
InterProiIPR016195. Pol/histidinol_Pase-like.
IPR023539. RNase_P_comp-3_arc.
IPR002738. RNase_P_p30.
[Graphical view]
PANTHERiPTHR13031. PTHR13031. 1 hit.
PfamiPF01876. RNase_P_p30. 1 hit.
[Graphical view]
SUPFAMiSSF89550. SSF89550. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiRNP3_THEKO
AccessioniPrimary (citable) accession number: Q5JH47
Entry historyi
Integrated into UniProtKB/Swiss-Prot: August 30, 2005
Last sequence update: February 15, 2005
Last modified: November 2, 2016
This is version 69 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.