Q5JH26 (RPIA_PYRKO) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Ribose-5-phosphate isomerase A
EC=5.3.1.6

Alternative name(s):
Phosphoriboisomerase A
Short name=PRI

Gene names

Name:	rpiA
Ordered Locus Names:	TK1426

Organism

Pyrococcus kodakaraensis (strain ATCC BAA-918 / JCM 12380 / KOD1) (Thermococcus kodakaraensis (strain KOD1))

Taxonomic identifier

69014 [NCBI]

Taxonomic lineage

Archaea › Euryarchaeota › Thermococci › Thermococcales › Thermococcaceae › Thermococcus

Protein attributes

Sequence length	229 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	D-ribose 5-phosphate = D-ribulose 5-phosphate. HAMAP MF_00170
Pathway	Carbohydrate degradation; pentose phosphate pathway; D-ribose 5-phosphate from D-ribulose 5-phosphate (non-oxidative stage): step 1/1. HAMAP MF_00170
Sequence similarities	Belongs to the ribose 5-phosphate isomerase family.

Ontologies

Keywords
Molecular function	Isomerase
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological process	pentose-phosphate shunt, non-oxidative branch Inferred from electronic annotation. Source: InterPro
Molecular function	ribose-5-phosphate isomerase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 229	229	Ribose-5-phosphate isomerase A HAMAP MF_00170		PRO_0000158518

Sequences

	Sequence		Length	Mass (Da)
	Q5JH26 [UniParc]. Last modified February 15, 2005. Version 1. Checksum: 5B02FDB8A882D8FC	FASTA	229	25,014
	10 20 30 40 50 60 MNVEEMKKAV AKEALKFIED EMVVGLGTGS TTAYFINYLG KLLMEGELED VYGVPTSHQA 70 80 90 100 110 120 RLLALEAGIP VVSLDEVDAI DIAVDGADEV DPHMNLIKGR GAALTMEKII EYRAGMFIVL 130 140 150 160 170 180 VDESKLVEYL GQKMPVPIEV IPAAWRAIAE ELEVFNATAE LRMAVKKDGP VVTDNGNFIL 190 200 210 220 DAKFARIEDP LDLEIELNTI PGVVENGIFA DIADIILVGT PEGVKRMER

References

[1]

"Complete genome sequence of the hyperthermophilic archaeon Thermococcus kodakaraensis KOD1 and comparison with Pyrococcus genomes." Fukui T., Atomi H., Kanai T., Matsumi R., Fujiwara S., Imanaka T. Genome Res. 15:352-363(2005) [PubMed: 15710748] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC BAA-918 / JCM 12380 / KOD1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AP006878 Genomic DNA. Translation: BAD85615.1.
RefSeq	YP_183839.1. NC_006624.1.
3D structure databases
ProteinModelPortal	Q5JH26.
SMR	Q5JH26. Positions 1-229.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	EBPYRT00000006626; EBPYRP00000006407; EBPYRG00000006625.
GeneID	3234473.
GenomeReviews	Gene locus TK1426 in contig AP006878_GR.
KEGG	tko:TK1426.
NMPDR	fig|69014.3.peg.1297.
Phylogenomic databases
eggNOG	arNOG07879.
GeneTree	EBGT00050000022434.
HOGENOM	HBG515603.
OMA	GGDPEYR.
PhylomeDB	Q5JH26.
ProtClustDB	PRK00702.
Enzyme and pathway databases
BioCyc	TKOD69014:TK1426-MONOMER.
Family and domain databases
HAMAP	MF_00170. Rib_5P_isom_A. [Tree]
InterPro	IPR004788. Ribose5P_isomerase_typA. IPR020672. Ribose5P_isomerase_typA_subgr. IPR014036. Tscrpt_reg_HTH_DeoR. [Graphical view]
KO	K01807.
PANTHER	PTHR11934. RpiA. 1 hit.
Pfam	PF00455. DeoR. 1 hit. PF06026. Rib_5-P_isom_A. 1 hit. [Graphical view]
TIGRFAMs	TIGR00021. RpiA. 1 hit.
ProtoNet	Search...

Entry information

Entry name

RPIA_PYRKO

Accession

Primary (citable) accession number: Q5JH26

Entry history

Integrated into UniProtKB/Swiss-Prot:	June 7, 2005
Last sequence update:	February 15, 2005
Last modified:	November 16, 2011
This is version 47 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program