Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

tRNA(Phe) 7-((3-amino-3-carboxypropyl)-4-demethylwyosine(37)-N(4))-methyltransferase 1

Gene

taw3-1

Organism
Thermococcus kodakarensis (strain ATCC BAA-918 / JCM 12380 / KOD1) (Pyrococcus kodakaraensis (strain KOD1))
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

S-adenosyl-L-methionine-dependent methyltransferase that acts as a component of the wyosine derivatives biosynthesis pathway. Probably methylates N-4 position of wybutosine-86 to produce wybutosine-72.UniRule annotation

Catalytic activityi

S-adenosyl-L-methionine + 7-((3S)-(3-amino-3-carboxypropyl))-4-demethylwyosine(37) in tRNA(Phe) = S-adenosyl-L-homocysteine + 7-((3S)-(3-amino-3-carboxypropyl))wyosine(37) in tRNA(Phe).UniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Methyltransferase, Transferase

Keywords - Biological processi

tRNA processing

Keywords - Ligandi

S-adenosyl-L-methionine

Enzyme and pathway databases

BioCyciTKOD69014:GH72-177-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
tRNA(Phe) 7-((3-amino-3-carboxypropyl)-4-demethylwyosine(37)-N(4))-methyltransferase 1UniRule annotation (EC:2.1.1.282UniRule annotation)
Alternative name(s):
tRNA wyosine derivatives biosynthesis protein Taw3 1UniRule annotation
Gene namesi
Name:taw3-1UniRule annotation
Ordered Locus Names:TK0175
OrganismiThermococcus kodakarensis (strain ATCC BAA-918 / JCM 12380 / KOD1) (Pyrococcus kodakaraensis (strain KOD1))
Taxonomic identifieri69014 [NCBI]
Taxonomic lineageiArchaeaEuryarchaeotaThermococciThermococcalesThermococcaceaeThermococcus
Proteomesi
  • UP000000536 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 198198tRNA(Phe) 7-((3-amino-3-carboxypropyl)-4-demethylwyosine(37)-N(4))-methyltransferase 1PRO_0000157097Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi69014.TK0175.

Structurei

3D structure databases

ProteinModelPortaliQ5JFK6.
SMRiQ5JFK6. Positions 4-195.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the TYW3 family.UniRule annotation

Phylogenomic databases

eggNOGiarCOG04156. Archaea.
COG1590. LUCA.
HOGENOMiHOG000222308.
InParanoidiQ5JFK6.
KOiK15450.
OMAiTMSSCSG.

Family and domain databases

Gene3Di3.30.1960.10. 1 hit.
HAMAPiMF_00266. TYW3_archaea. 1 hit.
InterProiIPR022908. Taw3.
IPR003827. tRNA_yW-synthesising.
[Graphical view]
PfamiPF02676. TYW3. 1 hit.
[Graphical view]
SUPFAMiSSF111278. SSF111278. 1 hit.

Sequencei

Sequence statusi: Complete.

Q5JFK6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MFLYTENFDE QKEKAMEGLR KALEEDKVDH DIIPLLEKIN ALQNYFTTSS
60 70 80 90 100
CSGRISVMEM PHFGDKVNSV WLGKWHREVR LEEVLEAVGK HRSGQLWFLV
110 120 130 140 150
RSPILHVGAR TLEDAVRLLN LAIGLGFKYS NIKSVSHKKL VVEIRSTERM
160 170 180 190
DVPLGENGEL WVDEAYIEKI VNLANAQVRR FKGKLKRLEE EIEKLQED
Length:198
Mass (Da):22,932
Last modified:February 15, 2005 - v1
Checksum:iA232CBE8562688E6
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP006878 Genomic DNA. Translation: BAD84364.1.
RefSeqiWP_011249130.1. NC_006624.1.

Genome annotation databases

EnsemblBacteriaiBAD84364; BAD84364; TK0175.
GeneIDi3234226.
KEGGitko:TK0175.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP006878 Genomic DNA. Translation: BAD84364.1.
RefSeqiWP_011249130.1. NC_006624.1.

3D structure databases

ProteinModelPortaliQ5JFK6.
SMRiQ5JFK6. Positions 4-195.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi69014.TK0175.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiBAD84364; BAD84364; TK0175.
GeneIDi3234226.
KEGGitko:TK0175.

Phylogenomic databases

eggNOGiarCOG04156. Archaea.
COG1590. LUCA.
HOGENOMiHOG000222308.
InParanoidiQ5JFK6.
KOiK15450.
OMAiTMSSCSG.

Enzyme and pathway databases

BioCyciTKOD69014:GH72-177-MONOMER.

Family and domain databases

Gene3Di3.30.1960.10. 1 hit.
HAMAPiMF_00266. TYW3_archaea. 1 hit.
InterProiIPR022908. Taw3.
IPR003827. tRNA_yW-synthesising.
[Graphical view]
PfamiPF02676. TYW3. 1 hit.
[Graphical view]
SUPFAMiSSF111278. SSF111278. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiTYW31_THEKO
AccessioniPrimary (citable) accession number: Q5JFK6
Entry historyi
Integrated into UniProtKB/Swiss-Prot: August 30, 2005
Last sequence update: February 15, 2005
Last modified: November 11, 2015
This is version 63 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.