Skip Header

You are using a version of Internet Explorer that may not display all features of this website. Please upgrade to a modern browser.
Contribute Send feedback
Read comments (?) or add your own

Q5JFI4 (PDAD_THEKO) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 61. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Pyruvoyl-dependent arginine decarboxylase

Short name=PvlArgDC
EC=4.1.1.19
Gene names
Name:pdaD
Ordered Locus Names:TK0149
OrganismThermococcus kodakaraensis (strain ATCC BAA-918 / JCM 12380 / KOD1) (Pyrococcus kodakaraensis (strain KOD1)) [Reference proteome] [HAMAP]
Taxonomic identifier69014 [NCBI]
Taxonomic lineageArchaeaEuryarchaeotaThermococciThermococcalesThermococcaceaeThermococcus

Protein attributes

Sequence length157 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

L-arginine = agmatine + CO2. HAMAP-Rule MF_01404

Cofactor

Pyruvoyl group By similarity. HAMAP-Rule MF_01404

Sequence similarities

Belongs to the PdaD family.

Ontologies

Keywords
   LigandPyruvate
   Molecular functionDecarboxylase
Lyase
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological_processarginine catabolic process

Inferred from electronic annotation. Source: InterPro

   Molecular_functionarginine decarboxylase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 4343Pyruvoyl-dependent arginine decarboxylase subunit beta By similarity
PRO_0000023334
Chain44 – 157114Pyruvoyl-dependent arginine decarboxylase subunit alpha By similarity
PRO_0000023335

Sites

Site43 – 442Cleavage (non-hydrolytic) By similarity

Amino acid modifications

Modified residue441Pyruvic acid (Ser) By similarity

Sequences

Sequence LengthMass (Da)Tools
Q5JFI4 [UniParc].

Last modified February 15, 2005. Version 1.
Checksum: 9D91137305B1126E

FASTA15717,062
        10         20         30         40         50         60 
MSWTTPKRAF IGAATAEGGT KLNAFDNALL KLGIGNVNLV KLSSVIPAHI EWMEKVHDVP 

        70         80         90        100        110        120 
IGMLLPTVYA HIESDEPGMT ISAALGVGIS KNNEGGLIYE YSGYCTKEEA EEMVRKMVEE 

       130        140        150 
GFRQRGWELG EFKVASAEIT VKDKPAAAIA VVVMFPY 

« Hide

References

[1]"Complete genome sequence of the hyperthermophilic archaeon Thermococcus kodakaraensis KOD1 and comparison with Pyrococcus genomes."
Fukui T., Atomi H., Kanai T., Matsumi R., Fujiwara S., Imanaka T.
Genome Res. 15:352-363(2005) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC BAA-918 / JCM 12380 / KOD1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AP006878 Genomic DNA. Translation: BAD84338.1.
RefSeqYP_182562.1. NC_006624.1.

3D structure databases

ProteinModelPortalQ5JFI4.
SMRQ5JFI4. Positions 3-43.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

IntActQ5JFI4. 1 interaction.
MINTMINT-8376658.
STRING69014.TK0149.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaBAD84338; BAD84338; TK0149.
GeneID3234595.
KEGGtko:TK0149.

Phylogenomic databases

eggNOGCOG1945.
HOGENOMHOG000012204.
KOK02626.

Enzyme and pathway databases

BioCycMetaCyc:MONOMER-16731.
TKOD69014:GH72-151-MONOMER.

Family and domain databases

Gene3D3.50.20.10. 1 hit.
HAMAPMF_01404. PvlArgDC.
InterProIPR016104. Pyr-dep_his/arg-deCO2ase.
IPR016105. Pyr-dep_his/arg-deCO2ase_sand.
IPR002724. Pyruvoyl-dep_arg_deCO2ase.
[Graphical view]
PfamPF01862. PvlArgDC. 1 hit.
[Graphical view]
PIRSFPIRSF005216. Pyruvoyl-dep_arg_deCO2ase. 1 hit.
ProDomPD010449. Pyruvoyl-dep_arg_deCO2ase. 1 hit.
[Graphical view] [Entries sharing at least one domain]
SUPFAMSSF56271. SSF56271. 1 hit.
TIGRFAMsTIGR00286. TIGR00286. 1 hit.
ProtoNetSearch...

Entry information

Entry namePDAD_THEKO
AccessionPrimary (citable) accession number: Q5JFI4
Entry history
Integrated into UniProtKB/Swiss-Prot: March 29, 2005
Last sequence update: February 15, 2005
Last modified: May 14, 2014
This is version 61 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families