ID   Q5JF90_THEKO            Unreviewed;       747 AA.
AC   Q5JF90;
DT   15-FEB-2005, integrated into UniProtKB/TrEMBL.
DT   15-FEB-2005, sequence version 1.
DT   27-MAR-2024, entry version 105.
DE   SubName: Full=Methyl-accepting chemotaxis protein {ECO:0000313|EMBL:BAD84827.1};
GN   OrderedLocusNames=TK0638 {ECO:0000313|EMBL:BAD84827.1};
OS   Thermococcus kodakarensis (strain ATCC BAA-918 / JCM 12380 / KOD1)
OS   (Pyrococcus kodakaraensis (strain KOD1)).
OC   Archaea; Euryarchaeota; Thermococci; Thermococcales; Thermococcaceae;
OC   Thermococcus.
OX   NCBI_TaxID=69014 {ECO:0000313|EMBL:BAD84827.1, ECO:0000313|Proteomes:UP000000536};
RN   [1] {ECO:0000313|EMBL:BAD84827.1, ECO:0000313|Proteomes:UP000000536}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC BAA-918 / JCM 12380 / KOD1
RC   {ECO:0000313|Proteomes:UP000000536};
RX   PubMed=15710748; DOI=10.1101/gr.3003105;
RA   Fukui T., Atomi H., Kanai T., Matsumi R., Fujiwara S., Imanaka T.;
RT   "Complete genome sequence of the hyperthermophilic archaeon Thermococcus
RT   kodakaraensis KOD1 and comparison with Pyrococcus genomes.";
RL   Genome Res. 15:352-363(2005).
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- SIMILARITY: Belongs to the methyl-accepting chemotaxis (MCP) protein
CC       family. {ECO:0000256|ARBA:ARBA00029447}.
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DR   EMBL; AP006878; BAD84827.1; -; Genomic_DNA.
DR   RefSeq; WP_011249589.1; NC_006624.1.
DR   AlphaFoldDB; Q5JF90; -.
DR   STRING; 69014.TK0638; -.
DR   EnsemblBacteria; BAD84827; BAD84827; TK0638.
DR   GeneID; 78447152; -.
DR   KEGG; tko:TK0638; -.
DR   PATRIC; fig|69014.16.peg.619; -.
DR   eggNOG; arCOG02320; Archaea.
DR   eggNOG; arCOG02362; Archaea.
DR   HOGENOM; CLU_000445_107_19_2; -.
DR   InParanoid; Q5JF90; -.
DR   OrthoDB; 342253at2157; -.
DR   PhylomeDB; Q5JF90; -.
DR   Proteomes; UP000000536; Chromosome.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR   GO; GO:0006935; P:chemotaxis; IEA:UniProtKB-KW.
DR   GO; GO:0007165; P:signal transduction; IEA:UniProtKB-KW.
DR   CDD; cd11386; MCP_signal; 1.
DR   CDD; cd12913; PDC1_MCP_like; 1.
DR   CDD; cd12912; PDC2_MCP_like; 1.
DR   Gene3D; 6.10.340.10; -; 1.
DR   Gene3D; 1.10.287.950; Methyl-accepting chemotaxis protein; 1.
DR   Gene3D; 3.30.450.20; PAS domain; 2.
DR   InterPro; IPR033479; dCache_1.
DR   InterPro; IPR003660; HAMP_dom.
DR   InterPro; IPR004089; MCPsignal_dom.
DR   InterPro; IPR029151; Sensor-like_sf.
DR   PANTHER; PTHR32089:SF92; LYSOZYME-LIKE PROTEIN-RELATED; 1.
DR   PANTHER; PTHR32089; METHYL-ACCEPTING CHEMOTAXIS PROTEIN MCPB; 1.
DR   Pfam; PF02743; dCache_1; 1.
DR   Pfam; PF00672; HAMP; 1.
DR   Pfam; PF00015; MCPsignal; 1.
DR   SMART; SM00283; MA; 1.
DR   SUPFAM; SSF58104; Methyl-accepting chemotaxis protein (MCP) signaling domain; 1.
DR   SUPFAM; SSF103190; Sensory domain-like; 1.
DR   PROSITE; PS50111; CHEMOTAXIS_TRANSDUC_2; 1.
DR   PROSITE; PS50885; HAMP; 1.
PE   3: Inferred from homology;
KW   Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW   Chemotaxis {ECO:0000256|ARBA:ARBA00022500};
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000000536};
KW   Transducer {ECO:0000256|ARBA:ARBA00023224, ECO:0000256|PROSITE-
KW   ProRule:PRU00284};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        7..28
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        317..338
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          390..442
FT                   /note="HAMP"
FT                   /evidence="ECO:0000259|PROSITE:PS50885"
FT   DOMAIN          461..718
FT                   /note="Methyl-accepting transducer"
FT                   /evidence="ECO:0000259|PROSITE:PS50111"
FT   COILED          458..489
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          676..744
FT                   /evidence="ECO:0000256|SAM:Coils"
SQ   SEQUENCE   747 AA;  82189 MW;  CB96B9E38FD86193 CRC64;
     MEFKKKIISI VVLGFVIVAV LTSGMLLYSE NNMANEIETQ LTPLMQQWAE QTVSAKSEAL
     AKEFQAFFDE VEALGTTTEK LAVIGIQELE SEGYKFGEGD YVEPLNEILM EHFETVAAAD
     SRISSVYFGD KYGNMFIYPE QELPEGYDPR VRPWYQEAVK AGKGVWSDPY QDASSGKWVV
     TYAVPIYRNG ELIGVIGLDV FIDTLVNEIK SVKVGETGYA YVVNEDGLII AHPNEQYVMK
     LNVFEQESLK PIADIVRSGK DSGVVTYEWQ GVKATAAGYK IPSTGWYVFT KVPTAEVTEG
     VMAVIRTVQD NTQKTTYMMI VLLLAISTVI VLAAYRLIST SLMPLVALGA AAQALAEGKL
     SEVKEKLRGI QYLEEDEIGM LIKAFESVSK DMVGTLQGIA EKLERLAEGD LSNGLSVEAK
     GELREIIEDV KDMSTKMREL LGNIVGLTEK LEKHANMLAQ VANDVTEAIN QVNEAVQQVS
     IEAQRQQENI NEITEGMRLV ADMSEESVRA MEEFEGAVNE VVHIADEGRQ KGEVSAQQIQ
     SIQEMMGNIE AAVNRVNEMS RSIEEITNVI TGIAEQTNLL ALNAAIEAAR AGEAGRGFAV
     VAQEIRNLAE ESKKAADNIK EIIGRMTDEI KDAVNATQRG VSVVSESSET LRETTEYLTN
     IAELISDTGA RLGHVKEQIL RTQEEVDKAL KALENLAASA EETTASAEEV SSAVEEQTAA
     IEELKRAADE LKKIVDELRR QTSNFRL
//