ID   Q5JER7_THEKO            Unreviewed;       461 AA.
AC   Q5JER7;
DT   15-FEB-2005, integrated into UniProtKB/TrEMBL.
DT   15-FEB-2005, sequence version 1.
DT   27-MAR-2024, entry version 98.
DE   SubName: Full=Alpha-amylase, GH13 family {ECO:0000313|EMBL:BAD86073.1};
GN   OrderedLocusNames=TK1884 {ECO:0000313|EMBL:BAD86073.1};
OS   Thermococcus kodakarensis (strain ATCC BAA-918 / JCM 12380 / KOD1)
OS   (Pyrococcus kodakaraensis (strain KOD1)).
OC   Archaea; Euryarchaeota; Thermococci; Thermococcales; Thermococcaceae;
OC   Thermococcus.
OX   NCBI_TaxID=69014 {ECO:0000313|EMBL:BAD86073.1, ECO:0000313|Proteomes:UP000000536};
RN   [1] {ECO:0000313|EMBL:BAD86073.1, ECO:0000313|Proteomes:UP000000536}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC BAA-918 / JCM 12380 / KOD1
RC   {ECO:0000313|Proteomes:UP000000536};
RX   PubMed=15710748; DOI=10.1101/gr.3003105;
RA   Fukui T., Atomi H., Kanai T., Matsumi R., Fujiwara S., Imanaka T.;
RT   "Complete genome sequence of the hyperthermophilic archaeon Thermococcus
RT   kodakaraensis KOD1 and comparison with Pyrococcus genomes.";
RL   Genome Res. 15:352-363(2005).
CC   -!- COFACTOR:
CC       Name=Ca(2+); Xref=ChEBI:CHEBI:29108;
CC         Evidence={ECO:0000256|ARBA:ARBA00001913};
CC   -!- SIMILARITY: Belongs to the glycosyl hydrolase 13 family.
CC       {ECO:0000256|ARBA:ARBA00008061}.
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DR   EMBL; AP006878; BAD86073.1; -; Genomic_DNA.
DR   RefSeq; WP_011250835.1; NC_006624.1.
DR   AlphaFoldDB; Q5JER7; -.
DR   SMR; Q5JER7; -.
DR   STRING; 69014.TK1884; -.
DR   CAZy; GH13; Glycoside Hydrolase Family 13.
DR   EnsemblBacteria; BAD86073; BAD86073; TK1884.
DR   GeneID; 78448415; -.
DR   KEGG; tko:TK1884; -.
DR   PATRIC; fig|69014.16.peg.1842; -.
DR   eggNOG; arCOG02954; Archaea.
DR   HOGENOM; CLU_024572_3_0_2; -.
DR   InParanoid; Q5JER7; -.
DR   OrthoDB; 18347at2157; -.
DR   PhylomeDB; Q5JER7; -.
DR   Proteomes; UP000000536; Chromosome.
DR   GO; GO:0004556; F:alpha-amylase activity; IEA:InterPro.
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR   CDD; cd11314; AmyAc_arch_bac_plant_AmyA; 1.
DR   Gene3D; 3.20.20.80; Glycosidases; 1.
DR   Gene3D; 2.60.40.1180; Golgi alpha-mannosidase II; 1.
DR   InterPro; IPR013776; A-amylase_thermo.
DR   InterPro; IPR015237; Alpha-amylase_C_pro.
DR   InterPro; IPR006046; Alpha_amylase.
DR   InterPro; IPR006047; Glyco_hydro_13_cat_dom.
DR   InterPro; IPR013780; Glyco_hydro_b.
DR   InterPro; IPR017853; Glycoside_hydrolase_SF.
DR   PANTHER; PTHR43447; ALPHA-AMYLASE; 1.
DR   PANTHER; PTHR43447:SF49; ALPHA-AMYLASE; 1.
DR   Pfam; PF09154; Alpha-amy_C_pro; 1.
DR   Pfam; PF00128; Alpha-amylase; 1.
DR   PIRSF; PIRSF001021; Alph-amls_thrmst; 1.
DR   PRINTS; PR00110; ALPHAAMYLASE.
DR   SMART; SM00642; Aamy; 1.
DR   SUPFAM; SSF51445; (Trans)glycosidases; 1.
DR   SUPFAM; SSF51011; Glycosyl hydrolase domain; 1.
PE   3: Inferred from homology;
KW   Glycosidase {ECO:0000256|ARBA:ARBA00023295};
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW   Reference proteome {ECO:0000313|Proteomes:UP000000536}.
FT   DOMAIN          36..381
FT                   /note="Glycosyl hydrolase family 13 catalytic"
FT                   /evidence="ECO:0000259|SMART:SM00642"
SQ   SEQUENCE   461 AA;  52214 MW;  FCC131A93DC03123 CRC64;
     MKKFVALLIT MFFVVSMAAV AQPASAAKYS ELEEGGVIMQ AFYWDVPAGG IWWDTIRSKI
     PEWYEAGISA IWIPPASKGM GGAYSMGYDP YDFFDLGEYN QKGTVETRFG SKQELINMIN
     TAHAYGIKVI ADIVINHRAG GDLEWNPFVG DYTWTDFSKV ASGKYTANYL DFHPNEVKCC
     DEGTFGGFPD IAHEKEWDQH WLWASDESYA AYLRSIGVDA WRFDYVKGYG AWVVKDWLNW
     WGGWAVGEYW DTNVDALLNW AYSSGAKVFD FPLYYKMDEA FDNTNIPALV DALQNGGTVV
     SRDPFKAVTF VANHDTDIIW NKYPAYAFIL TYEGQPVIFY RDYEEWLNKD KLNNLIWIHD
     HLAGGSTSIV YYDSDELIFV RNGDSKRPGL ITYINLGSSK VGRWVYVPKF AGACIHEYTG
     NLGGWVDKYV ESSGWVYLEA PAYDPASGQY GYTVWSYCGV G
//