Q5JEC9 (RNP4_PYRKO) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Ribonuclease P protein component 4
Short name=RNase P component 4
EC=3.1.26.5

Gene names

Name:	rnp4
Ordered Locus Names:	TK0031

Organism

Pyrococcus kodakaraensis (strain ATCC BAA-918 / JCM 12380 / KOD1) (Thermococcus kodakaraensis (strain KOD1)) [Reference proteome] [HAMAP]

Taxonomic identifier

69014 [NCBI]

Taxonomic lineage

cellular organisms › Archaea › Euryarchaeota › Thermococci › Thermococcales › Thermococcaceae › Thermococcus › Thermococcus kodakarensis

Protein attributes

Sequence length	132 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends By similarity. HAMAP-Rule MF_00757
Catalytic activity	Endonucleolytic cleavage of RNA, removing 5'-extranucleotides from tRNA precursor. HAMAP-Rule MF_00757
Subunit structure	Consists of a catalytic RNA component and at least 4 protein subunits Potential.
Sequence similarities	Belongs to the eukaryotic/archaeal RNase P protein component 4 family.

Ontologies

Keywords
Biological process	tRNA processing
Molecular function	Hydrolase
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	tRNA 5'-leader removal Inferred from electronic annotation. Source: HAMAP
Molecular_function	ribonuclease P activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 132	132	Ribonuclease P protein component 4 HAMAP-Rule MF_00757		PRO_0000153861

Sequences

	Sequence		Length	Mass (Da)
	Q5JEC9 [UniParc]. Last modified February 15, 2005. Version 1. Checksum: 34E76891439704CF	FASTA	132	15,785
	10 20 30 40 50 60 MGKKDIRRKE QREKKRIARE RVETLFTLAE RVFPYSPELA NRYVEIALSV QQKAKIRMPR 70 80 90 100 110 120 KWKRRYCKKC HSFLVPGVNA RVRLRDKPYP HVVITCLNCG NIMRYPYLRE KKARRKYASK 130 STENGNGPDW TS

References

[1]

"Complete genome sequence of the hyperthermophilic archaeon Thermococcus kodakaraensis KOD1 and comparison with Pyrococcus genomes." Fukui T., Atomi H., Kanai T., Matsumi R., Fujiwara S., Imanaka T. Genome Res. 15:352-363(2005) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC BAA-918 / JCM 12380 / KOD1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AP006878 Genomic DNA. Translation: BAD84220.1.
RefSeq	YP_182444.1. NC_006624.1.
3D structure databases
ProteinModelPortal	Q5JEC9.
SMR	Q5JEC9. Positions 17-108.
ModBase	Search...
Protein-protein interaction databases
STRING	69014.TK0031.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	BAD84220; BAD84220; TK0031.
GeneID	3234434.
KEGG	tko:TK0031.
Phylogenomic databases
eggNOG	COG2023.
HOGENOM	HOG000230709.
KO	K03540.
OMA	PRKWKRR.
ProtClustDB	PRK03954.
Family and domain databases
HAMAP	MF_00757. RNase_P_4.
InterPro	IPR016432. RNase_P_comp-4. IPR007175. Rpr2. [Graphical view]
PANTHER	PTHR14742. PTHR14742. 1 hit.
Pfam	PF04032. Rpr2. 1 hit. [Graphical view]
PIRSF	PIRSF004878. RNase_P_4. 1 hit.
ProtoNet	Search...

Entry information

Entry name

RNP4_PYRKO

Accession

Primary (citable) accession number: Q5JEC9

Entry history

Integrated into UniProtKB/Swiss-Prot:	August 30, 2005
Last sequence update:	February 15, 2005
Last modified:	May 1, 2013
This is version 49 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program