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Q5JE38

- GPI_THEKO

UniProt

Q5JE38 - GPI_THEKO

Protein

Glucose-6-phosphate isomerase

Gene

pgiA

Organism
Thermococcus kodakaraensis (strain ATCC BAA-918 / JCM 12380 / KOD1) (Pyrococcus kodakaraensis (strain KOD1))
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi
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    • History
      Entry version 68 (01 Oct 2014)
      Sequence version 1 (15 Feb 2005)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    D-glucose 6-phosphate = D-fructose 6-phosphate.UniRule annotation

    Pathwayi

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Metal bindingi88 – 881IronUniRule annotation
    Metal bindingi90 – 901IronUniRule annotation
    Metal bindingi97 – 971IronUniRule annotation
    Metal bindingi136 – 1361IronUniRule annotation

    GO - Molecular functioni

    1. glucose-6-phosphate isomerase activity Source: UniProtKB-HAMAP
    2. iron ion binding Source: InterPro

    GO - Biological processi

    1. gluconeogenesis Source: UniProtKB-HAMAP
    2. glycolytic process Source: UniProtKB-HAMAP

    Keywords - Molecular functioni

    Isomerase

    Keywords - Biological processi

    Gluconeogenesis, Glycolysis

    Keywords - Ligandi

    Iron, Metal-binding

    Enzyme and pathway databases

    BioCyciTKOD69014:GH72-1124-MONOMER.
    UniPathwayiUPA00109; UER00181.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Glucose-6-phosphate isomeraseUniRule annotation (EC:5.3.1.9UniRule annotation)
    Short name:
    GPIUniRule annotation
    Alternative name(s):
    Phosphoglucose isomeraseUniRule annotation
    Short name:
    PGIUniRule annotation
    Phosphohexose isomeraseUniRule annotation
    Short name:
    PHIUniRule annotation
    Gene namesi
    Name:pgiAUniRule annotation
    Ordered Locus Names:TK1111
    OrganismiThermococcus kodakaraensis (strain ATCC BAA-918 / JCM 12380 / KOD1) (Pyrococcus kodakaraensis (strain KOD1))
    Taxonomic identifieri69014 [NCBI]
    Taxonomic lineageiArchaeaEuryarchaeotaThermococciThermococcalesThermococcaceaeThermococcus
    ProteomesiUP000000536: Chromosome

    Subcellular locationi

    Cytoplasm UniRule annotation

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cytoplasm

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 189189Glucose-6-phosphate isomerasePRO_0000185359Add
    BLAST

    Interactioni

    Subunit structurei

    Homodimer.UniRule annotation

    Protein-protein interaction databases

    STRINGi69014.TK1111.

    Structurei

    3D structure databases

    ProteinModelPortaliQ5JE38.
    SMRiQ5JE38. Positions 1-189.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the archaeal-type GPI family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG2140.
    HOGENOMiHOG000243903.
    KOiK06859.
    OMAiYPADAGH.

    Family and domain databases

    Gene3Di2.60.120.10. 1 hit.
    HAMAPiMF_01410. G6P_isomerase_arch.
    InterProiIPR010551. G6P_isomerase_prok.
    IPR016758. G6P_isomerase_subgr.
    IPR014710. RmlC-like_jellyroll.
    IPR011051. RmlC_Cupin.
    [Graphical view]
    PfamiPF06560. GPI. 1 hit.
    [Graphical view]
    PIRSFiPIRSF019325. Glucose-6-phosphate_isomerase. 1 hit.
    SUPFAMiSSF51182. SSF51182. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    Q5JE38-1 [UniParc]FASTAAdd to Basket

    « Hide

    MEYKRPIGLD IDLETGVIPG AKKLVRRLSD LKGYFLDEEA YNELLKEDPV    50
    VYEVYAIEQE EKEGDLNFAT TVLYPGKVGK EFFFTKGHFH AKPDRAEIYY 100
    GIKGKGGMLL QTPEGEAEWI PMGPGTVVYV PPYWAHRTVN TGNEPFIFLA 150
    IYPADAGHDY GSIKEKGFSK IVIEEDGEVK VVDNPRWKE 189
    Length:189
    Mass (Da):21,422
    Last modified:February 15, 2005 - v1
    Checksum:i59AC54948A905052
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AP006878 Genomic DNA. Translation: BAD85300.1.
    RefSeqiYP_183524.1. NC_006624.1.

    Genome annotation databases

    EnsemblBacteriaiBAD85300; BAD85300; TK1111.
    GeneIDi3234743.
    KEGGitko:TK1111.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AP006878 Genomic DNA. Translation: BAD85300.1 .
    RefSeqi YP_183524.1. NC_006624.1.

    3D structure databases

    ProteinModelPortali Q5JE38.
    SMRi Q5JE38. Positions 1-189.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 69014.TK1111.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai BAD85300 ; BAD85300 ; TK1111 .
    GeneIDi 3234743.
    KEGGi tko:TK1111.

    Phylogenomic databases

    eggNOGi COG2140.
    HOGENOMi HOG000243903.
    KOi K06859.
    OMAi YPADAGH.

    Enzyme and pathway databases

    UniPathwayi UPA00109 ; UER00181 .
    BioCyci TKOD69014:GH72-1124-MONOMER.

    Family and domain databases

    Gene3Di 2.60.120.10. 1 hit.
    HAMAPi MF_01410. G6P_isomerase_arch.
    InterProi IPR010551. G6P_isomerase_prok.
    IPR016758. G6P_isomerase_subgr.
    IPR014710. RmlC-like_jellyroll.
    IPR011051. RmlC_Cupin.
    [Graphical view ]
    Pfami PF06560. GPI. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF019325. Glucose-6-phosphate_isomerase. 1 hit.
    SUPFAMi SSF51182. SSF51182. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. "Complete genome sequence of the hyperthermophilic archaeon Thermococcus kodakaraensis KOD1 and comparison with Pyrococcus genomes."
      Fukui T., Atomi H., Kanai T., Matsumi R., Fujiwara S., Imanaka T.
      Genome Res. 15:352-363(2005) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC BAA-918 / JCM 12380 / KOD1.

    Entry informationi

    Entry nameiGPI_THEKO
    AccessioniPrimary (citable) accession number: Q5JE38
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: June 7, 2005
    Last sequence update: February 15, 2005
    Last modified: October 1, 2014
    This is version 68 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3