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Q5JDN6 (PRNK_THEKO) Reviewed, UniProtKB/Swiss-Prot

Last modified June 11, 2014. Version 52. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Polyribonucleotide 5'-hydroxyl-kinase TK1956

EC=2.7.1.78
Alternative name(s):
Polynucleotide kinase TK1956
Gene names
Ordered Locus Names:TK1956
OrganismThermococcus kodakaraensis (strain ATCC BAA-918 / JCM 12380 / KOD1) (Pyrococcus kodakaraensis (strain KOD1)) [Reference proteome] [HAMAP]
Taxonomic identifier69014 [NCBI]
Taxonomic lineageArchaeaEuryarchaeotaThermococciThermococcalesThermococcaceaeThermococcus

Protein attributes

Sequence length351 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Polynucleotide kinase that can phosphorylate the 5'-hydroxyl groups of both single-stranded RNA (ssRNA) and single-stranded DNA (ssDNA). Exhibits a strong preference for ssRNA By similarity.

Catalytic activity

ATP + 5'-dephospho-DNA = ADP + 5'-phospho-DNA.

ATP + 5'-dephospho-RNA = ADP + 5'-phospho-RNA.

Cofactor

Divalent cation By similarity.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 351351Polyribonucleotide 5'-hydroxyl-kinase TK1956
PRO_0000376018

Regions

Nucleotide binding34 – 418ATP Potential

Sequences

Sequence LengthMass (Da)Tools
Q5JDN6 [UniParc].

Last modified February 15, 2005. Version 1.
Checksum: 792F87FD047132AE

FASTA35138,564
        10         20         30         40         50         60 
MNKARYTQDV PEDRIKLLES IASYNKPFTL MVVGGVDSGK STLITFLGNE LLSLGFKVAV 

        70         80         90        100        110        120 
VDSDVGQKGV LPPGTISLAI PEGPFESMSE LEGVAHYFVG TTAPSQFIGE MAVGVKRMVE 

       130        140        150        160        170        180 
IARNVADVVL IDTTGFVTGV GAEMKRLKAE LVKPDIIAVI HSGELSGLVK ALEPYGGVIE 

       190        200        210        220        230        240 
LAVSETVKRY PLEERRNLRA EKWRNYFRDS QLVEFSASEV AITGTSLFHG IPLNADENEL 

       250        260        270        280        290        300 
LEKAFGWLVV AGWKNKGYTV VKADVEKFPR AHSRELKAID FEKLSNLLVG LIDGEGLCMG 

       310        320        330        340        350 
VGVLKWINFS EGRLQILTPV RDLSGVREIR FGRIRVTEEG EELGLLRRDE L 

« Hide

References

[1]"Complete genome sequence of the hyperthermophilic archaeon Thermococcus kodakaraensis KOD1 and comparison with Pyrococcus genomes."
Fukui T., Atomi H., Kanai T., Matsumi R., Fujiwara S., Imanaka T.
Genome Res. 15:352-363(2005) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC BAA-918 / JCM 12380 / KOD1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AP006878 Genomic DNA. Translation: BAD86145.1.
RefSeqYP_184369.1. NC_006624.1.

3D structure databases

ProteinModelPortalQ5JDN6.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING69014.TK1956.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaBAD86145; BAD86145; TK1956.
GeneID3235264.
KEGGtko:TK1956.

Phylogenomic databases

eggNOGCOG1341.
HOGENOMHOG000074023.
KOK06947.
OMAFIGEITP.

Enzyme and pathway databases

BioCycTKOD69014:GH72-1995-MONOMER.

Family and domain databases

Gene3D3.40.50.300. 1 hit.
InterProIPR029007. MobB-typ_P-loop.
IPR027417. P-loop_NTPase.
[Graphical view]
PfamPF03205. MobB. 1 hit.
[Graphical view]
SUPFAMSSF52540. SSF52540. 1 hit.
ProtoNetSearch...

Entry information

Entry namePRNK_THEKO
AccessionPrimary (citable) accession number: Q5JDN6
Entry history
Integrated into UniProtKB/Swiss-Prot: May 26, 2009
Last sequence update: February 15, 2005
Last modified: June 11, 2014
This is version 52 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program