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Protein

Ribonuclease P protein component 1

Gene

rnp1

Organism
Thermococcus kodakarensis (strain ATCC BAA-918 / JCM 12380 / KOD1) (Pyrococcus kodakaraensis (strain KOD1))
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends.UniRule annotation

Catalytic activityi

Endonucleolytic cleavage of RNA, removing 5'-extranucleotides from tRNA precursor.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionEndonuclease, Hydrolase, Nuclease
Biological processtRNA processing

Names & Taxonomyi

Protein namesi
Recommended name:
Ribonuclease P protein component 1UniRule annotation (EC:3.1.26.5UniRule annotation)
Short name:
RNase P component 1UniRule annotation
Alternative name(s):
Rpp29UniRule annotation
Gene namesi
Name:rnp1UniRule annotation
Ordered Locus Names:TK1533
OrganismiThermococcus kodakarensis (strain ATCC BAA-918 / JCM 12380 / KOD1) (Pyrococcus kodakaraensis (strain KOD1))
Taxonomic identifieri69014 [NCBI]
Taxonomic lineageiArchaeaEuryarchaeotaThermococciThermococcalesThermococcaceaeThermococcus
Proteomesi
  • UP000000536 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001284381 – 125Ribonuclease P protein component 1Add BLAST125

Proteomic databases

PRIDEiQ5JDH8

Interactioni

Subunit structurei

Consists of a catalytic RNA component and at least 4-5 protein subunits.UniRule annotation

Protein-protein interaction databases

STRINGi69014.TK1533

Structurei

3D structure databases

ProteinModelPortaliQ5JDH8
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the eukaryotic/archaeal RNase P protein component 1 family.UniRule annotation

Phylogenomic databases

eggNOGiarCOG00784 Archaea
COG1588 LUCA
HOGENOMiHOG000231353
InParanoidiQ5JDH8
KOiK03538
OMAiWHELIGL
OrthoDBiPOG093Z0M9M

Family and domain databases

Gene3Di2.30.30.210, 1 hit
HAMAPiMF_00754 RNase_P_1, 1 hit
InterProiView protein in InterPro
IPR002730 RNase_P/MRP_p29
IPR036980 RNase_P/MRP_p29_sf
IPR023538 RNP1
IPR023534 Rof/RNase_P-like
PfamiView protein in Pfam
PF01868 UPF0086, 1 hit
SMARTiView protein in SMART
SM00538 POP4, 1 hit
SUPFAMiSSF101744 SSF101744, 1 hit

Sequencei

Sequence statusi: Complete.

Q5JDH8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRRNGKERKD RTAGRPQRQG QEVAGRAWIF RGAHRGRVTR KNIIWHELIG
60 70 80 90 100
LKAKVIRASH PELVGIEGYV LDETRNTLVL VGDRVWVVPK DVVEIEFDLG
110 120
NEKIRVNGKD LVGRPEMRLK KRWRK
Length:125
Mass (Da):14,568
Last modified:February 15, 2005 - v1
Checksum:i9017FFEA5A01F6F2
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP006878 Genomic DNA Translation: BAD85722.1

Genome annotation databases

EnsemblBacteriaiBAD85722; BAD85722; TK1533
KEGGitko:TK1533
PATRICifig|69014.16.peg.1493

Similar proteinsi

Entry informationi

Entry nameiRNP1_THEKO
AccessioniPrimary (citable) accession number: Q5JDH8
Entry historyiIntegrated into UniProtKB/Swiss-Prot: August 30, 2005
Last sequence update: February 15, 2005
Last modified: May 23, 2018
This is version 78 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
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Main funding by: National Institutes of Health