Reviewed, UniProtKB/Swiss-Prot Q5JDH8 (RNP1_PYRKO)

Names and origin

Protein names

Recommended name:
    Ribonuclease P protein component 1
      Short name=RNase P component 1
    EC=3.1.26.5

Gene names

Name:	rnp1
Ordered Locus Names:	TK1533

Organism

Pyrococcus kodakaraensis (Thermococcus kodakaraensis) [Complete proteome] [HAMAP]

Taxonomic identifier

311400 [NCBI]

Taxonomic lineage

Archaea › Euryarchaeota › Thermococci › Thermococcales › Thermococcaceae › Thermococcus

Protein attributes

Sequence length	125 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends By similarity.
Catalytic activity	Endonucleolytic cleavage of RNA, removing 5'-extranucleotides from tRNA precursor. HAMAP MF_00754
Subunit structure	Consists of a catalytic RNA component and at least 4 protein subunits Potential.
Sequence similarities	Belongs to the eukaryotic/archaeal RNase P protein component 1 family.

Ontologies

Keywords
Biological process	tRNA processing
Molecular function	Hydrolase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	mRNA cleavage Inferred from electronic annotation. Source: InterPro rRNA processing Inferred from electronic annotation. Source: InterPro tRNA 5'-leader removal Inferred from electronic annotation. Source: HAMAP
Cellular component	ribonuclease MRP complex Inferred from electronic annotation. Source: InterPro ribonuclease P complex Inferred from electronic annotation. Source: InterPro
Molecular function	RNA binding Inferred from electronic annotation. Source: InterPro ribonuclease P activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 125	125	Ribonuclease P protein component 1 HAMAP MF_00754		PRO_0000128438

Sequences

	Sequence		Length	Mass (Da)
	Q5JDH8-1 [UniParc]. Last modified February 15, 2005. Version 1. Checksum: 9017FFEA5A01F6F2	FASTA	125	14,568
	10 20 30 40 50 60 MRRNGKERKD RTAGRPQRQG QEVAGRAWIF RGAHRGRVTR KNIIWHELIG LKAKVIRASH 70 80 90 100 110 120 PELVGIEGYV LDETRNTLVL VGDRVWVVPK DVVEIEFDLG NEKIRVNGKD LVGRPEMRLK KRWRK

References

[1]

"Complete genome sequence of the hyperthermophilic archaeon Thermococcus kodakaraensis KOD1 and comparison with Pyrococcus genomes." Fukui T., Atomi H., Kanai T., Matsumi R., Fujiwara S., Imanaka T. Genome Res. 15:352-363(2005) [PubMed: 15710748] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: KOD1.

Cross-references

Sequence databases
EMBLGenBankDDBJ	AP006878 Genomic DNA. Translation: BAD85722.1.
RefSeq	YP_183946.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	Q5JDH8.
Genome annotation databases
GeneID	3233700.
GenomeReviews	Gene locus TK1533 in contig AP006878_GR.
KEGG	tko:TK1533.
NMPDR	fig|69014.3.peg.585.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	Q5JDH8.
OMA	LDETRNT.
Enzyme and pathway databases
BioCyc	TKOD69014:TK1533-MON.
BRENDA	3.1.26.5. 192130.
Family and domain databases
HAMAP	MF_00754. [Tree]
InterPro	IPR002730. RNase_P/MRP_p29-sub_euk/arc. [Graphical view]
Gene3D	G3DSA:2.30.30.210. RNase_P_Rpp29. 1 hit.
Pfam	PF01868. UPF0086. 1 hit. [Graphical view]
ProDom	PD009163. UPF0086. 1 hit. [Graphical view] [Entries sharing at least one domain]
ProtoNet	Search...

Entry information

Entry name

RNP1_PYRKO

Accession

Primary (citable) accession number: Q5JDH8

Entry history

Integrated into UniProtKB/Swiss-Prot:	August 30, 2005
Last sequence update:	February 15, 2005
Last modified:	November 3, 2009
This is version 27 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)