Q5JDH8 (RNP1_PYRKO) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Ribonuclease P protein component 1
Short name=RNase P component 1
EC=3.1.26.5

Gene names

Name:	rnp1
Ordered Locus Names:	TK1533

Organism

Pyrococcus kodakaraensis (strain ATCC BAA-918 / JCM 12380 / KOD1) (Thermococcus kodakaraensis (strain KOD1))

Taxonomic identifier

69014 [NCBI]

Taxonomic lineage

Archaea › Euryarchaeota › Thermococci › Thermococcales › Thermococcaceae › Thermococcus

Protein attributes

Sequence length	125 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends By similarity. HAMAP MF_00754
Catalytic activity	Endonucleolytic cleavage of RNA, removing 5'-extranucleotides from tRNA precursor. HAMAP MF_00754
Subunit structure	Consists of a catalytic RNA component and at least 4 protein subunits Potential.
Sequence similarities	Belongs to the eukaryotic/archaeal RNase P protein component 1 family.

Ontologies

Keywords
Biological process	tRNA processing
Molecular function	Hydrolase
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological process	mRNA cleavage Inferred from electronic annotation. Source: InterPro rRNA processing Inferred from electronic annotation. Source: InterPro tRNA 5'-leader removal Inferred from electronic annotation. Source: InterPro
Cellular component	ribonuclease MRP complex Inferred from electronic annotation. Source: InterPro ribonuclease P complex Inferred from electronic annotation. Source: InterPro
Molecular function	RNA binding Inferred from electronic annotation. Source: InterPro ribonuclease P activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 125	125	Ribonuclease P protein component 1 HAMAP MF_00754		PRO_0000128438

Sequences

	Sequence		Length	Mass (Da)
	Q5JDH8 [UniParc]. Last modified February 15, 2005. Version 1. Checksum: 9017FFEA5A01F6F2	FASTA	125	14,568
	10 20 30 40 50 60 MRRNGKERKD RTAGRPQRQG QEVAGRAWIF RGAHRGRVTR KNIIWHELIG LKAKVIRASH 70 80 90 100 110 120 PELVGIEGYV LDETRNTLVL VGDRVWVVPK DVVEIEFDLG NEKIRVNGKD LVGRPEMRLK KRWRK

References

[1]

"Complete genome sequence of the hyperthermophilic archaeon Thermococcus kodakaraensis KOD1 and comparison with Pyrococcus genomes." Fukui T., Atomi H., Kanai T., Matsumi R., Fujiwara S., Imanaka T. Genome Res. 15:352-363(2005) [PubMed: 15710748] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC BAA-918 / JCM 12380 / KOD1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AP006878 Genomic DNA. Translation: BAD85722.1.
RefSeq	YP_183946.1. NC_006624.1.
3D structure databases
ProteinModelPortal	Q5JDH8.
SMR	Q5JDH8. Positions 36-125.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	EBPYRT00000007605; EBPYRP00000007386; EBPYRG00000007604.
GeneID	3233700.
GenomeReviews	Gene locus TK1533 in contig AP006878_GR.
KEGG	tko:TK1533.
NMPDR	fig|69014.3.peg.585.
Phylogenomic databases
eggNOG	arNOG12604.
GeneTree	EBGT00050000023214.
HOGENOM	HBG704950.
OMA	LDETRNT.
PhylomeDB	Q5JDH8.
ProtClustDB	PRK03879.
Enzyme and pathway databases
BioCyc	TKOD69014:TK1533-MONOMER.
Family and domain databases
HAMAP	MF_00754. RNase_P_1. [Tree]
InterPro	IPR002730. RNase_P/MRP_p29. IPR023538. RNase_P_comp-1. IPR023534. Rof/RNase_P-like. [Graphical view]
Gene3D	G3DSA:2.30.30.210. RNase_P_Rpp29. 1 hit.
KO	K03538.
Pfam	PF01868. UPF0086. 1 hit. [Graphical view]
SUPFAM	SSF101744. RNase_P_Rpp29. 1 hit.
ProtoNet	Search...

Entry information

Entry name

RNP1_PYRKO

Accession

Primary (citable) accession number: Q5JDH8

Entry history

Integrated into UniProtKB/Swiss-Prot:	August 30, 2005
Last sequence update:	February 15, 2005
Last modified:	December 14, 2011
This is version 44 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program