Q5JDG7 (ACYP_PYRKO) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Acylphosphatase
EC=3.6.1.7

Alternative name(s):
Acylphosphate phosphohydrolase

Gene names

Name:	acyP
Ordered Locus Names:	TK2031

Organism

Pyrococcus kodakaraensis (strain ATCC BAA-918 / JCM 12380 / KOD1) (Thermococcus kodakaraensis (strain KOD1))

Taxonomic identifier

69014 [NCBI]

Taxonomic lineage

Archaea › Euryarchaeota › Thermococci › Thermococcales › Thermococcaceae › Thermococcus

Protein attributes

Sequence length	91 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	An acylphosphate + H2O = a carboxylate + phosphate. HAMAP MF_01450
Sequence similarities	Belongs to the acylphosphatase family. Contains 1 acylphosphatase-like domain.

Ontologies

Keywords
Molecular function	Hydrolase
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Molecular function	acylphosphatase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 91	91	Acylphosphatase HAMAP MF_01450		PRO_0000158561
Regions
	Domain	5 – 91	87	Acylphosphatase-like
Sites
	Active site	20	1	By similarity
	Active site	38	1	By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q5JDG7 [UniParc]. Last modified February 15, 2005. Version 1. Checksum: 6C277AE5C4C43838	FASTA	91	10,297
	10 20 30 40 50 60 MKRVRAHLRI YGRVQGVGFR WSMSREARKL GVHGWVRNLP DGTVEAVIEG DPERVEALIG 70 80 90 WAHQGPPLAR VTRVEVKWEE PEGLEGFKVV G

References

[1]

"Complete genome sequence of the hyperthermophilic archaeon Thermococcus kodakaraensis KOD1 and comparison with Pyrococcus genomes." Fukui T., Atomi H., Kanai T., Matsumi R., Fujiwara S., Imanaka T. Genome Res. 15:352-363(2005) [PubMed: 15710748] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC BAA-918 / JCM 12380 / KOD1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AP006878 Genomic DNA. Translation: BAD86220.1.
RefSeq	YP_184444.1. NC_006624.1.
3D structure databases
ProteinModelPortal	Q5JDG7.
SMR	Q5JDG7. Positions 4-91.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	EBPYRT00000007225; EBPYRP00000007006; EBPYRG00000007224.
GeneID	3235065.
GenomeReviews	Gene locus TK2031 in contig AP006878_GR.
KEGG	tko:TK2031.
NMPDR	fig|69014.3.peg.1890.
Phylogenomic databases
eggNOG	arNOG12401.
GeneTree	EBGT00050000022948.
HOGENOM	HBG750266.
OMA	ALIGWAH.
PhylomeDB	Q5JDG7.
ProtClustDB	PRK14436.
Enzyme and pathway databases
BioCyc	TKOD69014:TK2031-MONOMER.
Family and domain databases
HAMAP	MF_01450. Acylphosphatase. [Tree]
InterPro	IPR020456. Acylphosphatase. IPR001792. Acylphosphatase-like. IPR017968. Acylphosphatase_CS. [Graphical view]
KO	K01512.
Pfam	PF00708. Acylphosphatase. 1 hit. [Graphical view]
PRINTS	PR00112. ACYLPHPHTASE.
SUPFAM	SSF54975. Acylphosphatase. 1 hit.
PROSITE	PS00150. ACYLPHOSPHATASE_1. 1 hit. PS00151. ACYLPHOSPHATASE_2. 1 hit. PS51160. ACYLPHOSPHATASE_3. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

ACYP_PYRKO

Accession

Primary (citable) accession number: Q5JDG7

Entry history

Integrated into UniProtKB/Swiss-Prot:	October 25, 2005
Last sequence update:	February 15, 2005
Last modified:	November 16, 2011
This is version 45 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program