Q5JDF5 (Q5JDF5_PYRKO) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
N5-carboxyaminoimidazole ribonucleotide mutase PIRNR PIRNR001338
Short name=N5-CAIR mutase PIRNR PIRNR001338
EC=5.4.99.18 PIRNR PIRNR001338

Gene names

Ordered Locus Names:

TK0836

Organism

Pyrococcus kodakaraensis (strain ATCC BAA-918 / JCM 12380 / KOD1) (Thermococcus kodakaraensis (strain KOD1))

Taxonomic identifier

69014 [NCBI]

Taxonomic lineage

Archaea › Euryarchaeota › Thermococci › Thermococcales › Thermococcaceae › Thermococcus

Protein attributes

Sequence length	174 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) By similarity. PIRNR PIRNR001338
Catalytic activity	5-carboxyamino-1-(5-phospho-D-ribosyl)imidazole = 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate. PIRNR PIRNR001338
Pathway	Purine metabolism; IMP biosynthesis via de novo pathway; 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate from 5-amino-1-(5-phospho-D-ribosyl)imidazole (N5-CAIR route): step 2/2. PIRNR PIRNR001338
Sequence similarities	Belongs to the AIR carboxylase family. PIRNR PIRNR001338

Ontologies

Keywords
Biological process	Purine biosynthesis PIRNR PIRNR001338
Molecular function	Isomerase PIRNR PIRNR001338
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological process	'de novo' IMP biosynthetic process Inferred from electronic annotation. Source: InterPro
Molecular function	5-(carboxyamino)imidazole ribonucleotide mutase activity Inferred from electronic annotation. Source: EC phosphoribosylaminoimidazole carboxylase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q5JDF5 [UniParc]. Last modified February 15, 2005. Version 1. Checksum: 51ADAFC7B15C055D	FASTA	174	18,943
	10 20 30 40 50 60 MPKVGIIMGS DSDLPVMKAA AEVLEEFGVD YEITIVSAHR TPERMFEYAK TAEERGIEVI 70 80 90 100 110 120 IAGAGGAAHL PGMTASITTL PVIGVPVKTS TLNGLDSLLS IVQMPRGVPV ATVAINNAKN 130 140 150 160 170 AALLALSILG VKYPEIREKL KEYRRRMREE VEEKAERLEE MGYEEYLQVT GQGK

References

[1]

"Complete genome sequence of the hyperthermophilic archaeon Thermococcus kodakaraensis KOD1 and comparison with Pyrococcus genomes." Fukui T., Atomi H., Kanai T., Matsumi R., Fujiwara S., Imanaka T. Genome Res. 15:352-363(2005) [PubMed: 15710748] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC BAA-918 / JCM 12380 / KOD1 and KOD1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AP006878 Genomic DNA. Translation: BAD85025.1.
RefSeq	YP_183249.1. NC_006624.1.
3D structure databases
ProteinModelPortal	Q5JDF5.
SMR	Q5JDF5. Positions 2-167.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	EBPYRT00000006415; EBPYRP00000006196; EBPYRG00000006414.
GeneID	3235913.
GenomeReviews	Gene locus TK0836 in contig AP006878_GR.
KEGG	tko:TK0836.
NMPDR	fig|69014.3.peg.1253.
Phylogenomic databases
eggNOG	arNOG10111.
GeneTree	EBGT00050000023138.
HOGENOM	HBG301965.
OMA	LIMGSDS.
PhylomeDB	Q5JDF5.
Enzyme and pathway databases
BioCyc	TKOD69014:TK0836-MONOMER.
Family and domain databases
InterPro	IPR024694. N5-CAIR_mutase_PurE. IPR000031. N5-CAIR_Mutase_PurE_dom. [Graphical view]
Gene3D	G3DSA:3.40.50.7700. AIR_carboxyl. 1 hit.
KO	K01588.
Pfam	PF00731. AIRC. 1 hit. [Graphical view]
PIRSF	PIRSF001338. AIR_carboxylase. 1 hit.
SMART	SM01001. AIRC. 1 hit. [Graphical view]
SUPFAM	SSF52255. AIR_carboxyl. 1 hit.
TIGRFAMs	TIGR01162. PurE. 1 hit.
ProtoNet	Search...

Entry information

Entry name

Q5JDF5_PYRKO

Accession

Primary (citable) accession number: Q5JDF5

Entry history

Integrated into UniProtKB/TrEMBL:	February 15, 2005
Last sequence update:	February 15, 2005
Last modified:	January 25, 2012
This is version 44 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)