ID   Q5J8M4_HUMAN            Unreviewed;       352 AA.
AC   Q5J8M4;
DT   15-FEB-2005, integrated into UniProtKB/TrEMBL.
DT   15-FEB-2005, sequence version 1.
DT   27-MAR-2024, entry version 90.
DE   RecName: Full=Rae1 protein homolog {ECO:0000256|ARBA:ARBA00030954};
DE   AltName: Full=mRNA-associated protein mrnp 41 {ECO:0000256|ARBA:ARBA00031875};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC   Homo.
OX   NCBI_TaxID=9606 {ECO:0000313|EMBL:AAR24621.1};
RN   [1] {ECO:0000313|EMBL:AAR24621.1}
RP   NUCLEOTIDE SEQUENCE.
RA   Kim J.W.;
RT   "Identification of a migration-inducing gene.";
RL   Submitted (JUL-2003) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton, spindle pole
CC       {ECO:0000256|ARBA:ARBA00004647}.
CC   -!- SIMILARITY: Belongs to the WD repeat rae1 family.
CC       {ECO:0000256|ARBA:ARBA00007830}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AY336091; AAR24621.1; -; mRNA.
DR   AlphaFoldDB; Q5J8M4; -.
DR   GO; GO:0000922; C:spindle pole; IEA:UniProtKB-SubCell.
DR   Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 1.
DR   InterPro; IPR020472; G-protein_beta_WD-40_rep.
DR   InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR   InterPro; IPR019775; WD40_repeat_CS.
DR   InterPro; IPR036322; WD40_repeat_dom_sf.
DR   InterPro; IPR001680; WD40_rpt.
DR   PANTHER; PTHR10971; MRNA EXPORT FACTOR AND BUB3; 1.
DR   PANTHER; PTHR10971:SF11; MRNA EXPORT FACTOR RAE1; 1.
DR   Pfam; PF00400; WD40; 3.
DR   PRINTS; PR00320; GPROTEINBRPT.
DR   SMART; SM00320; WD40; 4.
DR   SUPFAM; SSF50978; WD40 repeat-like; 1.
DR   PROSITE; PS00678; WD_REPEATS_1; 2.
DR   PROSITE; PS50082; WD_REPEATS_2; 3.
DR   PROSITE; PS50294; WD_REPEATS_REGION; 1.
PE   2: Evidence at transcript level;
KW   Cell cycle {ECO:0000256|ARBA:ARBA00022776};
KW   Cell division {ECO:0000256|ARBA:ARBA00022776};
KW   Mitosis {ECO:0000256|ARBA:ARBA00022776};
KW   Repeat {ECO:0000256|ARBA:ARBA00022737};
KW   WD repeat {ECO:0000256|ARBA:ARBA00022574, ECO:0000256|PROSITE-
KW   ProRule:PRU00221}.
FT   REPEAT          66..107
FT                   /note="WD"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT   REPEAT          107..150
FT                   /note="WD"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT   REPEAT          260..294
FT                   /note="WD"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
SQ   SEQUENCE   352 AA;  39479 MW;  0EADD80070C2232C CRC64;
     MFGSATTDNH NPMKDIEVTS SPDDSIGCLS FSPPTLPGNF LIAGSWANDV RCWEVQDSGQ
     TIPKAQQMHT GPVLDVCWSD DGSKVFTASC DKTAKMWDLS SNQTIQIAQH DAPVKTIHWI
     KAPNYSCVMT GSWDKTLKFW DTRSSNPMMV LQLPERCYCA DVIYPMAVVA TAERGLIVYQ
     LENQPSEFRR IESPLKHQHR CVAIFKDKQN KPTGFALGSI EGRVAIHYIN PPNPAKDNFT
     FKCHRSNGTN TSAPQDIYAV NGIAFHPVHG TLATVGSDGR FSFWDKDART KLKTSEQLDQ
     PISACCFNHN GNIFAYASSY DWSKGHEFYN PQKKNYIFLR NAAEELKPRN KK
//