Q5ISC7 (Q5ISC7_HUMAN) Unreviewed, UniProtKB/TrEMBL
Last modified
July 27, 2011.
Version 54.
History...
Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order
Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize orderNames and origin
| Protein names | Submitted name: Predicted NUP98/PRRX2 fusion protein EMBL AAV84357.1 |
| Organism | Homo sapiens (Human) EMBL AAV84357.1 |
| Taxonomic identifier | 9606 [NCBI] |
| Taxonomic lineage | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Protein attributes
| Sequence length | 268 AA. |
| Sequence status | Fragment. |
| Protein existence | Evidence at transcript level |
General annotation (Comments)
| Subcellular location | Nucleus By similarity RuleBase RU000682. |
| Sequence similarities | Contains 1 homeobox DNA-binding domain. SAAS SAAS003654 |
Ontologies
| Keywords | |
|---|---|
| Cellular component | Nucleus RuleBase RU000682 SAAS SAAS003654 |
| Domain | Homeobox RuleBase RU000682 SAAS SAAS003654 |
| Ligand | DNA-binding RuleBase RU000682 SAAS SAAS003654 |
| Molecular function | Developmental protein SAAS SAAS003654 |
| Gene Ontology (GO) | |
| Biological process | multicellular organismal development Inferred from electronic annotation. Source: UniProtKB-KW |
| Cellular component | nucleus Inferred from electronic annotation. Source: UniProtKB-SubCell |
| Molecular function | sequence-specific DNA binding Inferred from electronic annotation. Source: InterPro sequence-specific DNA binding transcription factor activityInferred from electronic annotation. Source: InterPro |
| Complete GO annotation... | |
Sequence annotation (Features)
| Feature key | Position(s) | Length | Description | Graphical view | Feature identifier | |||
Experimental info | ||||||||
|---|---|---|---|---|---|---|---|---|
| Non-terminal residue | 1 | 1 | EMBL AAV84357.1 | |||||
| Non-terminal residue | 268 | 1 | EMBL AAV84357.1 | |||||
Sequences
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References
| [1] | "A new translocation t(9;11)(q34;p15) fuses NUP98 to a novel homeobox partner gene, PRRX2, in a therapy-related acute myeloid leukemia." Gervais C., Mauvieux L., Perrusson N., Helias C., Struski S., Leymarie V., Lioure B., Lessard M. Leukemia 19:145-148(2005) [PubMed: 15496970] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. |
Cross-references
Sequence databases | |
|---|---|
| EMBL GenBank DDBJ | AY662674 mRNA. Translation: AAV84357.1. |
3D structure databases | |
| ProteinModelPortal | Q5ISC7. |
| ModBase | Search... |
Protein-protein interaction databases | |
| STRING | Q5ISC7. |
Protocols and materials databases | |
| StructuralBiologyKnowledgebase | Search... |
Phylogenomic databases | |
| HOVERGEN | HBG021349. |
Family and domain databases | |
| InterPro | IPR003654. Homeo_OAR. IPR001356. Homeobox. IPR017970. Homeobox_CS. IPR009057. Homeodomain-like. IPR012287. Homeodomain-rel. [Graphical view] |
| Gene3D | G3DSA:1.10.10.60. Homeodomain-rel. 1 hit. |
| Pfam | PF00046. Homeobox. 1 hit. PF03826. OAR. 1 hit. [Graphical view] |
| SMART | SM00389. HOX. 1 hit. [Graphical view] |
| SUPFAM | SSF46689. Homeodomain_like. 1 hit. |
| PROSITE | PS00027. HOMEOBOX_1. 1 hit. PS50071. HOMEOBOX_2. 1 hit. PS50803. OAR. 1 hit. [Graphical view] |
| ProtoNet | Search... |
Entry information
| Entry name | Q5ISC7_HUMAN | ||||||||
| Accession | Primary (citable) accession number: Q5ISC7 | ||||||||
| Entry history |
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| Entry status | Unreviewed (UniProtKB/TrEMBL) | ||||||||
| Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. | ||||||||

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