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Unreviewed, UniProtKB/TrEMBL Q5ISC7 (Q5ISC7_HUMAN)

Last modified September 23, 2008. Version 30. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data | Customize display text xml rdf/xml gff fasta
Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information

Names and origin

Protein namesSubmitted name:
    Predicted NUP98/PRRX2 fusion protein EMBL AAV84357.1
OrganismHomo sapiens (Human) EMBL AAV84357.1
Taxonomic identifier9606 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Protein attributes

Sequence length268 AA.
Sequence statusFragment.
Sequence processingThe displayed sequence is not processed.
Protein existenceEvidence at transcript level.

General annotation (Comments)

Subcellular location

Nucleus. Spearmint SPM003654

NucleusBy similarity. RuleBase RU000682V4

Sequence similarities

Contains 1 homeobox DNA-binding domain. Spearmint SPM003654

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Experimental info

Non-terminal residue11 EMBL AAV84357.1
Non-terminal residue2681 EMBL AAV84357.1

Sequences

Sequence LengthMass (Da)Tools
Q5ISC7-1 [UniParc].

Last modified February 15, 2005. Version 1.
Checksum: D613D91CDD6F1B5B

FASTA26828,114
        10         20         30         40         50         60 
GVTQASQPGG LFGTATNTST GTAFGTGTGL FGQTNTGFGA VGSTLFGNNK LTTFGSSTTS 

        70         80         90        100        110        120 
APSFGTTSGG LFGFGTNTSG NSIFGSKPAP GTLGTGLGAG FGTGECPSPG RGSAAKRKKK 

       130        140        150        160        170        180 
QRRNRTTFNS SQLQALERVF ERTHYPDAFV REELARRVNL SEARVQVWFQ NRRAKFRRNE 

       190        200        210        220        230        240 
RAMLASRSAS LLKSYSQEAA IEQPVAPRPT ALSPDYLSWT ASSPYSTVPP YSPGSSGPAT 

       250        260 
PGVNMANSIA SLRLKAKEFS LHHSQVPT 

« Hide

References

[1]"A new translocation t(9;11)(q34;p15) fuses NUP98 to a novel homeobox partner gene, PRRX2, in a therapy-related acute myeloid leukemia."
Gervais C., Mauvieux L., Perrusson N., Helias C., Struski S., Leymarie V., Lioure B., Lessard M.
Leukemia 19:145-148(2005) [PubMed: 15496970] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE.
+Additional computationally mapped references.

Cross-references

Sequence databases

AY662674 mRNA. Translation: AAV84357.1.
UniGeneHs.660115

3D structure databases

SMRQ5ISC7. Positions 120-178.
ModBaseSearch...

Organism-specific databases

HGNCHGNC:21338. PRRX2.
GeneCardsSearch...

Phylogenomic databases

HOVERGENQ5ISC7.

Family and domain databases

InterProIPR003654. Homeo_OAR.
IPR001356. Homeobox.
IPR012287. Homeodomain-rel.
IPR000047. HTH_lambrepressr.
[Graphical view]
Gene3DG3DSA:1.10.10.60. Homeodomain-rel. 1 hit.
PfamPF00046. Homeobox. 1 hit.
PF03826. OAR. 1 hit.
[Graphical view]
PRINTSPR00024. HOMEOBOX.
PR00031. HTHREPRESSR.
ProDomPD000010. Homeobox. 1 hit.
[Graphical view] [Entries sharing at least one domain]
SMARTSM00389. HOX. 1 hit.
[Graphical view]
PROSITEPS00027. HOMEOBOX_1. 1 hit.
PS50071. HOMEOBOX_2. 1 hit.
PS50803. OAR. 1 hit.
[Graphical view]

Entry information

Entry nameQ5ISC7_HUMAN
AccessionPrimary (citable) accession number: Q5ISC7
Entry history
Integrated into UniProtKB/TrEMBL: February 15, 2005
Last sequence update: February 15, 2005
Last modified: September 23, 2008
This is version 30 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information