Q5IFH9 (Q5IFH9_MACMU) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names	Submitted name: Cytochrome P450 17 alpha-hydroxylase EMBL AAW45723.1
Organism	Macaca mulatta (Rhesus macaque) EMBL AAW45723.1
Taxonomic identifier	9544 [NCBI]
Taxonomic lineage	Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Cercopithecidae › Cercopithecinae › Macaca

Protein attributes

Sequence length	508 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

General annotation (Comments)

Sequence similarities

Belongs to the cytochrome P450 family. RuleBase RU000461

Ontologies

Keywords
Ligand	Heme RuleBase RU000461 Iron Metal-binding
Molecular function	Monooxygenase RuleBase RU003700 Oxidoreductase
Gene Ontology (GO)
Molecular function	electron carrier activity Inferred from electronic annotation. Source: InterPro heme binding Inferred from electronic annotation. Source: InterPro monooxygenase activity Inferred from electronic annotation. Source: UniProtKB-KW oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q5IFH9 [UniParc]. Last modified May 10, 2005. Version 1. Checksum: 92D7FFDF81398063	FASTA	508	57,619
	10 20 30 40 50 60 MWELVALLLL TLAYLFWPKR RCPGAKYPKS LLSLPLVGSL PFLPRHGHMH NNFFKLQKKY 70 80 90 100 110 120 GPIYSVRMGT KTTVIVGHHQ LAKEVLIKKG KDFSGRPQVT TLDILSNNRK GIAFADYGAH 130 140 150 160 170 180 WQLHRRLAMA TFALFKDGDQ KLEKIICQEI STLCDMLATH NGQTIDISFP VFVAITNVIS 190 200 210 220 230 240 LICFNISYKN GDPELKIVHN YNEGIIDSLG KESLVDLFPW LKVFPNKTLE KLKRHVKTRN 250 260 270 280 290 300 DLLTKIFENY KEKFHSDSIT NMLDVLMQAK MNSDNGNAGP DQDSELLSDN HILTTIGDIF 310 320 330 340 350 360 GAGVETTTSV VKWIVAFLLH NPQVKKKLYE EIDQNVGFSR TPTISDRNRL LLLEATIREV 370 380 390 400 410 420 LRIRPVAPML IPHKANVDSS IGEFAVDKGT HVIINLWALH HNEKEWHQPD QFMPERFLNP 430 440 450 460 470 480 AGTQLISPSL SYLPFGAGPR SCIGEILARQ ELFLIMAWLL QRFDLEVPDD GQLPSLEGNP 490 500 KVVFLIDSFK VKIKVRQAWR EAQAEGST

References

[1]	"Isolation of marmoset p450c17 cDNA and gene regulation in vitro." Pattison J.C., Conely A.J., Bird I.M. Endocr. Res. 30:737-743(2005) Cited for: NUCLEOTIDE SEQUENCE.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AY746983 mRNA. Translation: AAW45723.1.
RefSeq	NP_001035322.1. NM_001040232.1.
UniGene	Mmu.2608.
3D structure databases
ProteinModelPortal	Q5IFH9.
ModBase	Search...
Protein-protein interaction databases
STRING	Q5IFH9.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	678693.
KEGG	mcc:678693.
Organism-specific databases
CTD	1586.
Phylogenomic databases
eggNOG	prNOG05096.
HOVERGEN	HBG106944.
InParanoid	Q5IFH9.
Family and domain databases
InterPro	IPR001128. Cyt_P450. IPR017972. Cyt_P450_CS. IPR002401. Cyt_P450_E_grp-I. [Graphical view]
Gene3D	G3DSA:1.10.630.10. Cyt_P450. 1 hit.
KO	K00512.
Pfam	PF00067. p450. 1 hit. [Graphical view]
PRINTS	PR00463. EP450I. PR00385. P450.
SUPFAM	SSF48264. Cytochrome_P450. 1 hit.
PROSITE	PS00086. CYTOCHROME_P450. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Q5IFH9_MACMU

Accession

Primary (citable) accession number: Q5IFH9

Entry history

Integrated into UniProtKB/TrEMBL:	May 10, 2005
Last sequence update:	May 10, 2005
Last modified:	November 16, 2011
This is version 41 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)