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Protein
Submitted name:

Cystic fibrosis transmembrane conductance regulator ATP-binding cassette subfamily C member 7

Gene

CFTR

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein predictedi

Functioni

GO - Molecular functioni

Complete GO annotation...

Keywords - Ligandi

ATP-bindingImported, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Submitted name:
Cystic fibrosis transmembrane conductance regulator ATP-binding cassette subfamily C member 7Imported
Submitted name:
Cystic fibrosis transmembrane conductance regulator/ATP-binding cassette sub-family C member 7Imported
Gene namesi
Name:CFTRImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

Expressioni

Gene expression databases

BgeeiQ5I6F9.

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000003084.

Structurei

3D structure databases

ProteinModelPortaliQ5I6F9.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Keywords - Domaini

TransmembraneImported

Family and domain databases

Gene3Di3.40.50.300. 1 hit.
InterProiIPR003439. ABC_transporter-like.
IPR009147. CFTR/ABCC7.
IPR027417. P-loop_NTPase.
[Graphical view]
PANTHERiPTHR24223:SF19. PTHR24223:SF19. 1 hit.
PfamiPF00005. ABC_tran. 1 hit.
[Graphical view]
SUPFAMiSSF52540. SSF52540. 1 hit.

Sequencei

Sequence statusi: Fragment.

Q5I6F9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
VGLRSVIEQF PGKLDFVLVD GGCVLSHGHK QLMCLARSVL SKAKILLLDE
60 70 80 90 100
PSAHLDPVTY QIIRRTLKQA FADCTVILCE HRIEAMLECQ QFLVIEENKV
110 120 130 140 150
RQYDSIQKLL NERSLFRQAI SPSDRVKLFP HRNSSKCKSK PQIAALKEET

EEEVQDTRL
Length:159
Mass (Da):18,157
Last modified:February 15, 2005 - v1
Checksum:iF9470470FBC047AF
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei1 – 11Imported

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY848828 Genomic DNA. Translation: AAW33655.1.
AY849794 Genomic DNA. Translation: AAW33782.1.
UniGeneiHs.489786.
Hs.621460.
Hs.661104.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY848828 Genomic DNA. Translation: AAW33655.1.
AY849794 Genomic DNA. Translation: AAW33782.1.
UniGeneiHs.489786.
Hs.621460.
Hs.661104.

3D structure databases

ProteinModelPortaliQ5I6F9.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000003084.

Chemistry

BindingDBiQ5I6F9.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Gene expression databases

BgeeiQ5I6F9.

Family and domain databases

Gene3Di3.40.50.300. 1 hit.
InterProiIPR003439. ABC_transporter-like.
IPR009147. CFTR/ABCC7.
IPR027417. P-loop_NTPase.
[Graphical view]
PANTHERiPTHR24223:SF19. PTHR24223:SF19. 1 hit.
PfamiPF00005. ABC_tran. 1 hit.
[Graphical view]
SUPFAMiSSF52540. SSF52540. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: Fa0458Imported.

Entry informationi

Entry nameiQ5I6F9_HUMAN
AccessioniPrimary (citable) accession number: Q5I6F9
Entry historyi
Integrated into UniProtKB/TrEMBL: February 15, 2005
Last sequence update: February 15, 2005
Last modified: June 24, 2015
This is version 60 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.