Q5I139 (PTPJ2_MDBVW) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Probable tyrosine phosphatase protein J2
Short name=PTP-J2
EC=3.1.3.48

Gene names

Name:

J3

Organism

Microplitis demolitor bracovirus (isolate Webb) (MdBV) [Reference proteome]

Taxonomic identifier

654919 [NCBI]

Taxonomic lineage

Viruses › dsDNA viruses, no RNA stage › Polydnaviridae › Bracovirus › Microplitis demolitor bracovirus

Virus host

Microplitis demolitor [TaxID: 69319]

Protein attributes

Sequence length	297 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	Protein tyrosine phosphate + H2O = protein tyrosine + phosphate.
Sequence similarities	Belongs to the protein-tyrosine phosphatase family. Contains 1 tyrosine-protein phosphatase domain.

Ontologies

Keywords
Molecular function	Hydrolase Protein phosphatase
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	peptidyl-tyrosine dephosphorylation Inferred from electronic annotation. Source: GOC
Molecular_function	protein tyrosine phosphatase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 297	297	Probable tyrosine phosphatase protein J2		PRO_0000405356
Regions
	Domain	21 – 286	266	Tyrosine-protein phosphatase
Sites
	Active site	227	1	Phosphocysteine intermediate By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q5I139 [UniParc]. Last modified February 15, 2005. Version 1. Checksum: 092EE3801466E015	FASTA	297	34,458
	10 20 30 40 50 60 MPIEDKRMRI MDFINFVRKP DSLSCIIQEY RAIVPEQEDG ASKSCNQAVN RAQDENNALP 70 80 90 100 110 120 IVRLVHSRVN LFSKEKVMSA RYVDGYNHKQ KFIITINSCE NNTDKYLQML WDNNVQIVVT 130 140 150 160 170 180 TSSHAEKNNF NRFWSLNERT VITYNNFQIE TLEIITKPHF VLTLLVLTDQ KGQARKLSHF 190 200 210 220 230 240 QYTAWPADGF SHDPKAFLDF FFNIDSLYAD LRKHKTIGNV GPITIDCIDN NSSSEVFCVL 250 260 270 280 290 DICLTEVKKT GMLSIANAVK KVRQKKYGCM NRLNDYVFCY HLIHAYLSMT FDIVKVR

References

[1]

"Polydnavirus genomes reflect their dual roles as mutualists and pathogens." Webb B.A., Strand M.R., Dickey S.E., Beck M.H., Hilgarth R.S., Barney W.E., Kadash K., Kroemer J.A., Lindstrom K.G., Rattanadechakul W., Shelby K.S., Thoetkiattikul H., Turnbull M.W., Witherell R.A. Virology 347:160-174(2006) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	AY875686 Genomic DNA. Translation: AAW51793.1.
RefSeq	YP_239389.1. NC_007036.1.
3D structure databases
ProteinModelPortal	Q5I139.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	5075822.
Phylogenomic databases
ProtClustDB	PHA2740.
Family and domain databases
InterPro	IPR000387. Tyr/Dual-sp_Pase. IPR000242. Tyr_Pase_rcpt/non-rcpt. [Graphical view]
Pfam	PF00102. Y_phosphatase. 1 hit. [Graphical view]
PRINTS	PR00700. PRTYPHPHTASE.
SMART	SM00194. PTPc. 1 hit. [Graphical view]
PROSITE	PS00383. TYR_PHOSPHATASE_1. False negative. PS50056. TYR_PHOSPHATASE_2. 1 hit. PS50055. TYR_PHOSPHATASE_PTP. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

PTPJ2_MDBVW

Accession

Primary (citable) accession number: Q5I139

Entry history

Integrated into UniProtKB/Swiss-Prot:	March 8, 2011
Last sequence update:	February 15, 2005
Last modified:	March 6, 2013
This is version 30 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Viral Protein Annotation Program