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Q5I128 (PTPN1_MDBVW) Reviewed, UniProtKB/Swiss-Prot

Last modified June 11, 2014. Version 37. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Probable tyrosine phosphatase protein N1

Short name=PTP-N1
EC=3.1.3.48
Gene names
Name:N3
OrganismMicroplitis demolitor bracovirus (isolate Webb) (MdBV) [Reference proteome]
Taxonomic identifier654919 [NCBI]
Taxonomic lineageVirusesdsDNA viruses, no RNA stagePolydnaviridaeBracovirus
Virus hostMicroplitis demolitor [TaxID: 69319]

Protein attributes

Sequence length318 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

Protein tyrosine phosphate + H2O = protein tyrosine + phosphate.

Sequence similarities

Belongs to the protein-tyrosine phosphatase family.

Contains 1 tyrosine-protein phosphatase domain.

Ontologies

Keywords
   Molecular functionHydrolase
Protein phosphatase
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Molecular_functionprotein tyrosine phosphatase activity

Inferred from electronic annotation. Source: UniProtKB-EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 318318Probable tyrosine phosphatase protein N1
PRO_0000405373

Regions

Domain26 – 292267Tyrosine-protein phosphatase

Sites

Active site2331Phosphocysteine intermediate By similarity

Sequences

Sequence LengthMass (Da)Tools
Q5I128 [UniParc].

Last modified February 15, 2005. Version 1.
Checksum: 0B1B9C6FECC4C9C0

FASTA31837,071
        10         20         30         40         50         60 
MVVNCFETCR AIDFWNRRNQ LNFPGIVRLE HHQVILKPFN GTWENSEKPE NQRKNRYNIR 

        70         80         90        100        110        120 
CWDHNRVILK SGSGSTSNYI HANYVDGFED DKKFIITQGP MEETCNDFWK AVWQNNCSII 

       130        140        150        160        170        180 
VMLTPTKGTN GEELCYQYWS LNEDSNIITE DFVIETVNTS VRPTYILTTL RITDKISNDS 

       190        200        210        220        230        240 
RRISHYQYTE WPVDETPTNH VDFIKFIKII NINRKKSGSN YQQQLLSPIV VHCSDGVKKT 

       250        260        270        280        290        300 
GIFCAVDISL NQLVLRKTVS LAKTAEKIRQ QRHSTISTPD DYLILQPGYY VLLYLLYKIL 

       310 
AIIKIKNCGE KKSRRKST 

« Hide

References

[1]"Polydnavirus genomes reflect their dual roles as mutualists and pathogens."
Webb B.A., Strand M.R., Dickey S.E., Beck M.H., Hilgarth R.S., Barney W.E., Kadash K., Kroemer J.A., Lindstrom K.G., Rattanadechakul W., Shelby K.S., Thoetkiattikul H., Turnbull M.W., Witherell R.A.
Virology 347:160-174(2006) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
[2]"Inhibitor kappaB-like proteins from a polydnavirus inhibit NF-kappaB activation and suppress the insect immune response."
Thoetkiattikul H., Beck M.H., Strand M.R.
Proc. Natl. Acad. Sci. U.S.A. 102:11426-11431(2005) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AY875689 Genomic DNA. Translation: AAW51807.1.
RefSeqYP_239400.1. NC_007039.1.

3D structure databases

ProteinModelPortalQ5I128.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID5075833.

Family and domain databases

Gene3D3.90.190.10. 1 hit.
InterProIPR029021. Prot-tyrosine_phosphatase-like.
IPR000387. Tyr/Dual-sp_Pase.
IPR000242. Tyr_Pase_rcpt/non-rcpt.
[Graphical view]
PfamPF00102. Y_phosphatase. 1 hit.
[Graphical view]
PRINTSPR00700. PRTYPHPHTASE.
SMARTSM00194. PTPc. 1 hit.
[Graphical view]
SUPFAMSSF52799. SSF52799. 1 hit.
PROSITEPS50056. TYR_PHOSPHATASE_2. 1 hit.
PS50055. TYR_PHOSPHATASE_PTP. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry namePTPN1_MDBVW
AccessionPrimary (citable) accession number: Q5I128
Entry history
Integrated into UniProtKB/Swiss-Prot: March 8, 2011
Last sequence update: February 15, 2005
Last modified: June 11, 2014
This is version 37 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programViral Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families