Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Probable tyrosine phosphatase protein N1

Gene

N3

Organism
Microplitis demolitor bracovirus (isolate Webb) (MdBV)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

Protein tyrosine phosphate + H2O = protein tyrosine + phosphate.

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei233 – 2331Phosphocysteine intermediatePROSITE-ProRule annotation

GO - Molecular functioni

  1. protein tyrosine phosphatase activity Source: UniProtKB-EC
Complete GO annotation...

Keywords - Molecular functioni

Hydrolase, Protein phosphatase

Names & Taxonomyi

Protein namesi
Recommended name:
Probable tyrosine phosphatase protein N1 (EC:3.1.3.48)
Short name:
PTP-N1
Gene namesi
Name:N3
OrganismiMicroplitis demolitor bracovirus (isolate Webb) (MdBV)
Taxonomic identifieri654919 [NCBI]
Taxonomic lineageiVirusesdsDNA viruses, no RNA stagePolydnaviridaeBracovirus
Virus hostiMicroplitis demolitor [TaxID: 69319]
ProteomesiUP000008168: Genome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 318318Probable tyrosine phosphatase protein N1PRO_0000405373Add
BLAST

Structurei

3D structure databases

ProteinModelPortaliQ5I128.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini26 – 292267Tyrosine-protein phosphatasePROSITE-ProRule annotationAdd
BLAST

Sequence similaritiesi

Contains 1 tyrosine-protein phosphatase domain.PROSITE-ProRule annotation

Family and domain databases

Gene3Di3.90.190.10. 1 hit.
InterProiIPR029021. Prot-tyrosine_phosphatase-like.
IPR000387. Tyr/Dual-sp_Pase.
IPR000242. Tyr_Pase_rcpt/non-rcpt.
[Graphical view]
PfamiPF00102. Y_phosphatase. 1 hit.
[Graphical view]
PRINTSiPR00700. PRTYPHPHTASE.
SMARTiSM00194. PTPc. 1 hit.
[Graphical view]
SUPFAMiSSF52799. SSF52799. 1 hit.
PROSITEiPS50056. TYR_PHOSPHATASE_2. 1 hit.
PS50055. TYR_PHOSPHATASE_PTP. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q5I128-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MVVNCFETCR AIDFWNRRNQ LNFPGIVRLE HHQVILKPFN GTWENSEKPE
60 70 80 90 100
NQRKNRYNIR CWDHNRVILK SGSGSTSNYI HANYVDGFED DKKFIITQGP
110 120 130 140 150
MEETCNDFWK AVWQNNCSII VMLTPTKGTN GEELCYQYWS LNEDSNIITE
160 170 180 190 200
DFVIETVNTS VRPTYILTTL RITDKISNDS RRISHYQYTE WPVDETPTNH
210 220 230 240 250
VDFIKFIKII NINRKKSGSN YQQQLLSPIV VHCSDGVKKT GIFCAVDISL
260 270 280 290 300
NQLVLRKTVS LAKTAEKIRQ QRHSTISTPD DYLILQPGYY VLLYLLYKIL
310
AIIKIKNCGE KKSRRKST
Length:318
Mass (Da):37,071
Last modified:February 15, 2005 - v1
Checksum:i0B1B9C6FECC4C9C0
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY875689 Genomic DNA. Translation: AAW51807.1.
RefSeqiYP_239400.1. NC_007039.1.

Genome annotation databases

GeneIDi5075833.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY875689 Genomic DNA. Translation: AAW51807.1.
RefSeqiYP_239400.1. NC_007039.1.

3D structure databases

ProteinModelPortaliQ5I128.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi5075833.

Family and domain databases

Gene3Di3.90.190.10. 1 hit.
InterProiIPR029021. Prot-tyrosine_phosphatase-like.
IPR000387. Tyr/Dual-sp_Pase.
IPR000242. Tyr_Pase_rcpt/non-rcpt.
[Graphical view]
PfamiPF00102. Y_phosphatase. 1 hit.
[Graphical view]
PRINTSiPR00700. PRTYPHPHTASE.
SMARTiSM00194. PTPc. 1 hit.
[Graphical view]
SUPFAMiSSF52799. SSF52799. 1 hit.
PROSITEiPS50056. TYR_PHOSPHATASE_2. 1 hit.
PS50055. TYR_PHOSPHATASE_PTP. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
  2. "Inhibitor kappaB-like proteins from a polydnavirus inhibit NF-kappaB activation and suppress the insect immune response."
    Thoetkiattikul H., Beck M.H., Strand M.R.
    Proc. Natl. Acad. Sci. U.S.A. 102:11426-11431(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].

Entry informationi

Entry nameiPTPN1_MDBVW
AccessioniPrimary (citable) accession number: Q5I128
Entry historyi
Integrated into UniProtKB/Swiss-Prot: March 8, 2011
Last sequence update: February 15, 2005
Last modified: January 7, 2015
This is version 39 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programViral Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.