Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Tetratricopeptide repeat protein 32

Gene

TTC32

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Names & Taxonomyi

Protein namesi
Recommended name:
Tetratricopeptide repeat protein 32
Short name:
TPR repeat protein 32
Gene namesi
Name:TTC32
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 2

Organism-specific databases

HGNCiHGNC:32954. TTC32.

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000183891.
PharmGKBiPA145147867.

Polymorphism and mutation databases

BioMutaiTTC32.
DMDMi74755518.

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002631001 – 151Tetratricopeptide repeat protein 32Add BLAST151

Proteomic databases

EPDiQ5I0X7.
MaxQBiQ5I0X7.
PaxDbiQ5I0X7.
PeptideAtlasiQ5I0X7.
PRIDEiQ5I0X7.

PTM databases

iPTMnetiQ5I0X7.
PhosphoSitePlusiQ5I0X7.

Expressioni

Gene expression databases

BgeeiENSG00000183891.
CleanExiHS_TTC32.
ExpressionAtlasiQ5I0X7. baseline and differential.
GenevisibleiQ5I0X7. HS.

Organism-specific databases

HPAiHPA036024.

Interactioni

Binary interactionsi

Show more details

Protein-protein interaction databases

BioGridi126236. 10 interactors.
IntActiQ5I0X7. 8 interactors.
STRINGi9606.ENSP00000333018.

Structurei

3D structure databases

ProteinModelPortaliQ5I0X7.
SMRiQ5I0X7.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Repeati8 – 41TPR 1Add BLAST34
Repeati58 – 91TPR 2Add BLAST34
Repeati92 – 125TPR 3Add BLAST34

Keywords - Domaini

Repeat, TPR repeat

Phylogenomic databases

eggNOGiKOG1124. Eukaryota.
COG0457. LUCA.
GeneTreeiENSGT00390000011905.
HOGENOMiHOG000068047.
HOVERGENiHBG056063.
InParanoidiQ5I0X7.
OMAiYIRQCAC.
OrthoDBiEOG091G0S8L.
PhylomeDBiQ5I0X7.

Family and domain databases

Gene3Di1.25.40.10. 1 hit.
InterProiView protein in InterPro
IPR013026. TPR-contain_dom.
IPR011990. TPR-like_helical_dom.
IPR001440. TPR_1.
IPR019734. TPR_repeat.
PfamiView protein in Pfam
PF00515. TPR_1. 1 hit.
SMARTiView protein in SMART
SM00028. TPR. 2 hits.
SUPFAMiSSF48452. SSF48452. 1 hit.
PROSITEiView protein in PROSITE
PS50005. TPR. 2 hits.
PS50293. TPR_REGION. 1 hit.

Sequencei

Sequence statusi: Complete.

Q5I0X7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MEGQRQESHA TLTLAQAHFN NGEYAEAEAL YSAYIRRCAC AASSDESPGS
60 70 80 90 100
KCSPEDLATA YNNRGQIKYF RVDFYEAMDD YTSAIEVQPN FEVPYYNRGL
110 120 130 140 150
ILYRLGYFDD ALEDFKKVLD LNPGFQDATL SLKQTILDKE EKQRRNVAKN

Y
Length:151
Mass (Da):17,296
Last modified:February 15, 2005 - v1
Checksum:i81BE35CDA095B2D9
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC057850 mRNA. Translation: AAH57850.1.
CCDSiCCDS33151.1.
RefSeqiNP_001008238.1. NM_001008237.2.
UniGeneiHs.591547.

Genome annotation databases

EnsembliENST00000333610; ENSP00000333018; ENSG00000183891.
GeneIDi130502.
KEGGihsa:130502.
UCSCiuc002rdg.4. human.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC057850 mRNA. Translation: AAH57850.1.
CCDSiCCDS33151.1.
RefSeqiNP_001008238.1. NM_001008237.2.
UniGeneiHs.591547.

3D structure databases

ProteinModelPortaliQ5I0X7.
SMRiQ5I0X7.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi126236. 10 interactors.
IntActiQ5I0X7. 8 interactors.
STRINGi9606.ENSP00000333018.

PTM databases

iPTMnetiQ5I0X7.
PhosphoSitePlusiQ5I0X7.

Polymorphism and mutation databases

BioMutaiTTC32.
DMDMi74755518.

Proteomic databases

EPDiQ5I0X7.
MaxQBiQ5I0X7.
PaxDbiQ5I0X7.
PeptideAtlasiQ5I0X7.
PRIDEiQ5I0X7.

Protocols and materials databases

DNASUi130502.
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000333610; ENSP00000333018; ENSG00000183891.
GeneIDi130502.
KEGGihsa:130502.
UCSCiuc002rdg.4. human.

Organism-specific databases

CTDi130502.
GeneCardsiTTC32.
HGNCiHGNC:32954. TTC32.
HPAiHPA036024.
neXtProtiNX_Q5I0X7.
OpenTargetsiENSG00000183891.
PharmGKBiPA145147867.
GenAtlasiSearch...

Phylogenomic databases

eggNOGiKOG1124. Eukaryota.
COG0457. LUCA.
GeneTreeiENSGT00390000011905.
HOGENOMiHOG000068047.
HOVERGENiHBG056063.
InParanoidiQ5I0X7.
OMAiYIRQCAC.
OrthoDBiEOG091G0S8L.
PhylomeDBiQ5I0X7.

Miscellaneous databases

GenomeRNAii130502.
PROiQ5I0X7.

Gene expression databases

BgeeiENSG00000183891.
CleanExiHS_TTC32.
ExpressionAtlasiQ5I0X7. baseline and differential.
GenevisibleiQ5I0X7. HS.

Family and domain databases

Gene3Di1.25.40.10. 1 hit.
InterProiView protein in InterPro
IPR013026. TPR-contain_dom.
IPR011990. TPR-like_helical_dom.
IPR001440. TPR_1.
IPR019734. TPR_repeat.
PfamiView protein in Pfam
PF00515. TPR_1. 1 hit.
SMARTiView protein in SMART
SM00028. TPR. 2 hits.
SUPFAMiSSF48452. SSF48452. 1 hit.
PROSITEiView protein in PROSITE
PS50005. TPR. 2 hits.
PS50293. TPR_REGION. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiTTC32_HUMAN
AccessioniPrimary (citable) accession number: Q5I0X7
Entry historyiIntegrated into UniProtKB/Swiss-Prot: December 12, 2006
Last sequence update: February 15, 2005
Last modified: March 15, 2017
This is version 103 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 2
    Human chromosome 2: entries, gene names and cross-references to MIM

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.