Q5I0K7 (ALG13_RAT) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
UDP-N-acetylglucosamine transferase subunit ALG13 homolog
EC=2.4.1.141

Alternative name(s):
Glycosyltransferase 28 domain-containing protein 1

Gene names

Name:	Alg13
Synonyms:	Glt28d1

Organism

Rattus norvegicus (Rat) [Reference proteome]

Taxonomic identifier

10116 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Glires › Rodentia › Sciurognathi › Muroidea › Muridae › Murinae › Rattus

Protein attributes

Sequence length	165 AA.
Sequence status	Complete.
Protein existence	Evidence at protein level

General annotation (Comments)

Function	May be involved in protein N-glycosylation, second step of the dolichol-linked oligosaccharide pathway By similarity.
Catalytic activity	UDP-N-acetyl-D-glucosamine + N-acetyl-D-glucosaminyl-diphosphodolichol = UDP + N,N'-diacetylchitobiosyl-diphosphodolichol.
Subunit structure	May interact with ALG14 By similarity.
Subcellular location	Endoplasmic reticulum By similarity. Note: Could be recruited to the cytosolic face of the endoplasmic reticulum membrane through its interaction with ALG14 By similarity.
Sequence similarities	Belongs to the glycosyltransferase 28 family.

Ontologies

Keywords
Cellular component	Endoplasmic reticulum
Molecular function	Glycosyltransferase Transferase
Technical term	Complete proteome Direct protein sequencing Reference proteome
Gene Ontology (GO)
Biological_process	lipid glycosylation Inferred from electronic annotation. Source: InterPro
Cellular_component	endoplasmic reticulum Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular_function	N-acetylglucosaminyldiphosphodolichol N-acetylglucosaminyltransferase activity Inferred from electronic annotation. Source: EC carbohydrate binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 165	165	UDP-N-acetylglucosamine transferase subunit ALG13 homolog		PRO_0000254575

Sequences

	Sequence		Length	Mass (Da)
	Q5I0K7 [UniParc]. Last modified February 15, 2005. Version 1. Checksum: 2BBFA7D967588B15	FASTA	165	18,329
	10 20 30 40 50 60 MKRAFVTVGT TSFDDLVARV VANDTVQILK SLGYNHLVLQ IGRGTVVPEP FSTEPFTLDV 70 80 90 100 110 120 YRYKESLKED LQQADLVISH AGAGSCLESL EKGKPLVVVV NEKLMNNHQF ELAKQLHKEG 130 140 150 160 HLFYCTCSML PGLLQSMDLS TLKCYPPGQP EKFSAFLDKV VGLQK

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." The MGC Project Team Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. Tissue: Liver.
[2]	Lubec G., Kang S.U. Submitted (JUL-2007) to UniProtKB Cited for: PROTEIN SEQUENCE OF 153-159, MASS SPECTROMETRY. Strain: Sprague-Dawley. Tissue: Brain.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	BC088233 mRNA. Translation: AAH88233.1.
IPI	IPI00373064.
RefSeq	NP_001013973.1. NM_001013951.1.
UniGene	Rn.29819.
3D structure databases
ProteinModelPortal	Q5I0K7.
ModBase	Search...
Protein-protein interaction databases
STRING	10116.ENSRNOP00000007969.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
Ensembl	ENSRNOT00000007968; ENSRNOP00000007969; ENSRNOG00000005753.
GeneID	300284.
KEGG	rno:300284.
Organism-specific databases
CTD	79868.
RGD	1359416. Alg13.
Phylogenomic databases
eggNOG	COG5017.
GeneTree	ENSGT00510000047493.
HOGENOM	HOG000192807.
HOVERGEN	HBG056051.
InParanoid	Q5I0K7.
KO	K07432.
OMA	VISHAGE.
OrthoDB	EOG44J2H7.
Gene expression databases
Genevestigator	Q5I0K7.
GermOnline	ENSRNOG00000005753. Rattus norvegicus.
Family and domain databases
InterPro	IPR007235. Glyco_trans_28_C. [Graphical view]
Pfam	PF04101. Glyco_tran_28_C. 1 hit. [Graphical view]
ProtoNet	Search...
Other
NextBio	646705.

Entry information

Entry name

ALG13_RAT

Accession

Primary (citable) accession number: Q5I0K7

Entry history

Integrated into UniProtKB/Swiss-Prot:	October 31, 2006
Last sequence update:	February 15, 2005
Last modified:	April 3, 2013
This is version 60 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Chordata Protein Annotation Program