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Protein

Coenzyme Q-binding protein COQ10 homolog B, mitochondrial

Gene

Coq10b

Organism
Rattus norvegicus (Rat)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

Required for the function of coenzyme Q in the respiratory chain. May serve as a chaperone or may be involved in the transport of Q6 from its site of synthesis to the catalytic sites of the respiratory complexes (By similarity).By similarity

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Recommended name:
Coenzyme Q-binding protein COQ10 homolog B, mitochondrial
Gene namesi
Name:Coq10b
OrganismiRattus norvegicus (Rat)
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Unplaced

Organism-specific databases

RGDi1359509. Coq10b.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane, Mitochondrion, Mitochondrion inner membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transit peptidei1 – 20MitochondrionSequence analysisAdd BLAST20
ChainiPRO_000022865021 – 240Coenzyme Q-binding protein COQ10 homolog B, mitochondrialAdd BLAST220

Proteomic databases

PaxDbiQ5I0I9.
PRIDEiQ5I0I9.

Expressioni

Gene expression databases

BgeeiENSRNOG00000014456.

Interactioni

Subunit structurei

Interacts with coenzyme Q.By similarity

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000050509.

Structurei

3D structure databases

ProteinModelPortaliQ5I0I9.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the COQ10 family.Curated

Keywords - Domaini

Transit peptide

Phylogenomic databases

eggNOGiKOG3177. Eukaryota.
COG2867. LUCA.
HOGENOMiHOG000261732.
HOVERGENiHBG081329.
InParanoidiQ5I0I9.
KOiK18588.
PhylomeDBiQ5I0I9.
TreeFamiTF314447.

Family and domain databases

Gene3Di3.30.530.20. 1 hit.
InterProiIPR005031. COQ10_START.
IPR023393. START-like_dom.
[Graphical view]
PfamiPF03364. Polyketide_cyc. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q5I0I9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAARTSQRTL ARVASGCRPK STTVTEARVR GSARNVRYLA PCGILMNRTL
60 70 80 90 100
APWASVLPKE ICARTFFRIT TPLVNKRKEY SERRIIGYSM QEMYDVVSGM
110 120 130 140 150
EDYKHFVPWC KKSDILSRRS GYCKTRLEIG FPPVLERYTS IVTLVKPHLV
160 170 180 190 200
KASCTDGKLF NHLETVWRFS PGLPGYPRTC TLDFSISFEF RSLLHSQLAT
210 220 230 240
LFFDEVVKQM VAAFERRACK LYGPETNIPR ELMLHEIHHT
Length:240
Mass (Da):27,601
Last modified:March 21, 2006 - v2
Checksum:i04ACAA0EE2BFB709
GO

Sequence cautioni

The sequence AAH88273 differs from that shown. Reason: Erroneous initiation.Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC088273 mRNA. Translation: AAH88273.1. Different initiation.
RefSeqiNP_001009671.1. NM_001009671.1.
UniGeneiRn.101706.

Genome annotation databases

GeneIDi301416.
KEGGirno:301416.
UCSCiRGD:1359509. rat.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC088273 mRNA. Translation: AAH88273.1. Different initiation.
RefSeqiNP_001009671.1. NM_001009671.1.
UniGeneiRn.101706.

3D structure databases

ProteinModelPortaliQ5I0I9.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000050509.

Proteomic databases

PaxDbiQ5I0I9.
PRIDEiQ5I0I9.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi301416.
KEGGirno:301416.
UCSCiRGD:1359509. rat.

Organism-specific databases

CTDi80219.
RGDi1359509. Coq10b.

Phylogenomic databases

eggNOGiKOG3177. Eukaryota.
COG2867. LUCA.
HOGENOMiHOG000261732.
HOVERGENiHBG081329.
InParanoidiQ5I0I9.
KOiK18588.
PhylomeDBiQ5I0I9.
TreeFamiTF314447.

Miscellaneous databases

PROiQ5I0I9.

Gene expression databases

BgeeiENSRNOG00000014456.

Family and domain databases

Gene3Di3.30.530.20. 1 hit.
InterProiIPR005031. COQ10_START.
IPR023393. START-like_dom.
[Graphical view]
PfamiPF03364. Polyketide_cyc. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiCQ10B_RAT
AccessioniPrimary (citable) accession number: Q5I0I9
Entry historyi
Integrated into UniProtKB/Swiss-Prot: March 21, 2006
Last sequence update: March 21, 2006
Last modified: November 30, 2016
This is version 74 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.