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Protein

Coenzyme Q-binding protein COQ10 homolog B, mitochondrial

Gene

Coq10b

Organism
Rattus norvegicus (Rat)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

Required for the function of coenzyme Q in the respiratory chain. May serve as a chaperone or may be involved in the transport of Q6 from its site of synthesis to the catalytic sites of the respiratory complexes (By similarity).By similarity

GO - Molecular functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Recommended name:
Coenzyme Q-binding protein COQ10 homolog B, mitochondrial
Gene namesi
Name:Coq10b
OrganismiRattus norvegicus (Rat)
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Unplaced

Organism-specific databases

RGDi1359509. Coq10b.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Membrane, Mitochondrion, Mitochondrion inner membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transit peptidei1 – 20MitochondrionSequence analysisAdd BLAST20
ChainiPRO_000022865021 – 240Coenzyme Q-binding protein COQ10 homolog B, mitochondrialAdd BLAST220

Proteomic databases

PaxDbiQ5I0I9.
PRIDEiQ5I0I9.

Interactioni

Subunit structurei

Interacts with coenzyme Q.By similarity

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000050509.

Structurei

3D structure databases

ProteinModelPortaliQ5I0I9.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the COQ10 family.Curated

Keywords - Domaini

Transit peptide

Phylogenomic databases

eggNOGiKOG3177. Eukaryota.
COG2867. LUCA.
HOGENOMiHOG000261732.
HOVERGENiHBG081329.
InParanoidiQ5I0I9.
KOiK18588.
PhylomeDBiQ5I0I9.
TreeFamiTF314447.

Family and domain databases

Gene3Di3.30.530.20. 1 hit.
InterProiView protein in InterPro
IPR005031. COQ10_START.
IPR023393. START-like_dom_sf.
PfamiView protein in Pfam
PF03364. Polyketide_cyc. 1 hit.

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q5I0I9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAARTSQRTL ARVASGCRPK STTVTEARVR GSARNVRYLA PCGILMNRTL
60 70 80 90 100
APWASVLPKE ICARTFFRIT TPLVNKRKEY SERRIIGYSM QEMYDVVSGM
110 120 130 140 150
EDYKHFVPWC KKSDILSRRS GYCKTRLEIG FPPVLERYTS IVTLVKPHLV
160 170 180 190 200
KASCTDGKLF NHLETVWRFS PGLPGYPRTC TLDFSISFEF RSLLHSQLAT
210 220 230 240
LFFDEVVKQM VAAFERRACK LYGPETNIPR ELMLHEIHHT
Length:240
Mass (Da):27,601
Last modified:March 21, 2006 - v2
Checksum:i04ACAA0EE2BFB709
GO

Sequence cautioni

The sequence AAH88273 differs from that shown. Reason: Erroneous initiation.Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC088273 mRNA. Translation: AAH88273.1. Different initiation.
RefSeqiNP_001009671.1. NM_001009671.1.
UniGeneiRn.101706.

Genome annotation databases

GeneIDi301416.
KEGGirno:301416.
UCSCiRGD:1359509. rat.

Similar proteinsi

Entry informationi

Entry nameiCQ10B_RAT
AccessioniPrimary (citable) accession number: Q5I0I9
Entry historyiIntegrated into UniProtKB/Swiss-Prot: March 21, 2006
Last sequence update: March 21, 2006
Last modified: November 22, 2017
This is version 77 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families