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Protein

Nucleolar complex protein 4 homolog

Gene

Noc4l

Organism
Rattus norvegicus (Rat)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Enzyme and pathway databases

ReactomeiR-RNO-6791226 Major pathway of rRNA processing in the nucleolus and cytosol

Names & Taxonomyi

Protein namesi
Recommended name:
Nucleolar complex protein 4 homolog
Short name:
NOC4 protein homolog
Alternative name(s):
NOC4-like protein
Nucleolar complex-associated protein 4-like protein
Gene namesi
Name:Noc4l
OrganismiRattus norvegicus (Rat)
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Chromosome 12

Organism-specific databases

RGDi1310661 Noc4l

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei296 – 316HelicalSequence analysisAdd BLAST21
Transmembranei347 – 367HelicalSequence analysisAdd BLAST21
Transmembranei375 – 395HelicalSequence analysisAdd BLAST21

Keywords - Cellular componenti

Membrane, Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001734861 – 516Nucleolar complex protein 4 homologAdd BLAST516

Proteomic databases

PaxDbiQ5I0I8
PRIDEiQ5I0I8

PTM databases

iPTMnetiQ5I0I8
PhosphoSitePlusiQ5I0I8

Expressioni

Gene expression databases

BgeeiENSRNOG00000037478
GenevisibleiQ5I0I8 RN

Interactioni

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000053566

Structurei

3D structure databases

SMRiQ5I0I8
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the CBF/MAK21 family.Curated

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiKOG2154 Eukaryota
ENOG410YJPG LUCA
GeneTreeiENSGT00390000016776
HOGENOMiHOG000158314
HOVERGENiHBG060855
InParanoidiQ5I0I8
KOiK14771
OMAiERNLDYP
OrthoDBiEOG091G07EE
PhylomeDBiQ5I0I8
TreeFamiTF105812

Family and domain databases

InterProiView protein in InterPro
IPR016024 ARM-type_fold
IPR005612 CCAAT-binding_factor
IPR027193 Noc4
PANTHERiPTHR12455 PTHR12455, 1 hit
PfamiView protein in Pfam
PF03914 CBF, 1 hit
SUPFAMiSSF48371 SSF48371, 4 hits

Sequencei

Sequence statusi: Complete.

Q5I0I8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MERQPASTGS RQELGRLLEA VLSNRGRANA VFDILAVLQS EDPEEIKEGV
60 70 80 90 100
RTCSRLFGTL LEREELFVGS LPCEDMALAG SQGATYKYKV WMRHRYHSCC
110 120 130 140 150
NRLEELLTHP SFQVKELALE TLMKFVQLEG AKPLEKPQWE SHYLFPRTLF
160 170 180 190 200
RAVVGGLLTP EDDHSLLISQ FCEYLEYDDI RYHAMQVATS ILARATSRQP
210 220 230 240 250
EVSLTFWNNA FTLLSAVNLP LQEHELTNFY VKHAQTSSKW KVVHLKEQRK
260 270 280 290 300
AFQEMWLGFL KHKLPLSLYK KVLVAMHDSI LPHLAQPTLM IDFLTSACDV
310 320 330 340 350
GGAISLLALN GLFILIHKHN LEYPDFYQRL YGLLDPSIFH VKYRARFFHL
360 370 380 390 400
ADLFLSSSHL PAYLVAAFAK RLARLALTAP PEALLMVLPL ICNLLRRHPA
410 420 430 440 450
CRVMVHRPQG PELDADPYDP TEKDPARSRA LESCLWELQT LQQHYHPEVS
460 470 480 490 500
RAASVINQAL SVPEVSIAPL LELTAYEIFE QDLKKMMPES VPLEFIPAKG
510
LLGRQDDLCT QFFCLS
Length:516
Mass (Da):58,862
Last modified:February 15, 2005 - v1
Checksum:i1D11D524C58510EA
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC088275 mRNA Translation: AAH88275.1
RefSeqiNP_001014151.1, NM_001014129.1
UniGeneiRn.8908

Genome annotation databases

EnsembliENSRNOT00000056725; ENSRNOP00000053566; ENSRNOG00000037478
GeneIDi360828
KEGGirno:360828
UCSCiRGD:1310661 rat

Similar proteinsi

Entry informationi

Entry nameiNOC4L_RAT
AccessioniPrimary (citable) accession number: Q5I0I8
Entry historyiIntegrated into UniProtKB/Swiss-Prot: August 16, 2005
Last sequence update: February 15, 2005
Last modified: March 28, 2018
This is version 89 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
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Main funding by: National Institutes of Health