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Protein

Nucleolar complex protein 4 homolog

Gene

Noc4l

Organism
Rattus norvegicus (Rat)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Enzyme and pathway databases

ReactomeiR-RNO-6791226. Major pathway of rRNA processing in the nucleolus.

Names & Taxonomyi

Protein namesi
Recommended name:
Nucleolar complex protein 4 homolog
Short name:
NOC4 protein homolog
Alternative name(s):
NOC4-like protein
Nucleolar complex-associated protein 4-like protein
Gene namesi
Name:Noc4l
OrganismiRattus norvegicus (Rat)
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Chromosome 12

Organism-specific databases

RGDi1310661. Noc4l.

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei296 – 31621HelicalSequence analysisAdd
BLAST
Transmembranei347 – 36721HelicalSequence analysisAdd
BLAST
Transmembranei375 – 39521HelicalSequence analysisAdd
BLAST

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane, Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 516516Nucleolar complex protein 4 homologPRO_0000173486Add
BLAST

Proteomic databases

PaxDbiQ5I0I8.
PRIDEiQ5I0I8.

PTM databases

iPTMnetiQ5I0I8.
PhosphoSiteiQ5I0I8.

Expressioni

Gene expression databases

BgeeiENSRNOG00000037478.
GenevisibleiQ5I0I8. RN.

Interactioni

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000053566.

Family & Domainsi

Sequence similaritiesi

Belongs to the CBF/MAK21 family.Curated

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiKOG2154. Eukaryota.
ENOG410YJPG. LUCA.
GeneTreeiENSGT00390000016776.
HOGENOMiHOG000158314.
HOVERGENiHBG060855.
InParanoidiQ5I0I8.
KOiK14771.
OMAiRRHPSCR.
OrthoDBiEOG091G07EE.
PhylomeDBiQ5I0I8.
TreeFamiTF105812.

Family and domain databases

InterProiIPR016024. ARM-type_fold.
IPR005612. CCAAT-binding_factor.
IPR027193. Noc4.
[Graphical view]
PANTHERiPTHR12455:SF0. PTHR12455:SF0. 1 hit.
PfamiPF03914. CBF. 1 hit.
[Graphical view]
SUPFAMiSSF48371. SSF48371. 4 hits.

Sequencei

Sequence statusi: Complete.

Q5I0I8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MERQPASTGS RQELGRLLEA VLSNRGRANA VFDILAVLQS EDPEEIKEGV
60 70 80 90 100
RTCSRLFGTL LEREELFVGS LPCEDMALAG SQGATYKYKV WMRHRYHSCC
110 120 130 140 150
NRLEELLTHP SFQVKELALE TLMKFVQLEG AKPLEKPQWE SHYLFPRTLF
160 170 180 190 200
RAVVGGLLTP EDDHSLLISQ FCEYLEYDDI RYHAMQVATS ILARATSRQP
210 220 230 240 250
EVSLTFWNNA FTLLSAVNLP LQEHELTNFY VKHAQTSSKW KVVHLKEQRK
260 270 280 290 300
AFQEMWLGFL KHKLPLSLYK KVLVAMHDSI LPHLAQPTLM IDFLTSACDV
310 320 330 340 350
GGAISLLALN GLFILIHKHN LEYPDFYQRL YGLLDPSIFH VKYRARFFHL
360 370 380 390 400
ADLFLSSSHL PAYLVAAFAK RLARLALTAP PEALLMVLPL ICNLLRRHPA
410 420 430 440 450
CRVMVHRPQG PELDADPYDP TEKDPARSRA LESCLWELQT LQQHYHPEVS
460 470 480 490 500
RAASVINQAL SVPEVSIAPL LELTAYEIFE QDLKKMMPES VPLEFIPAKG
510
LLGRQDDLCT QFFCLS
Length:516
Mass (Da):58,862
Last modified:February 15, 2005 - v1
Checksum:i1D11D524C58510EA
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC088275 mRNA. Translation: AAH88275.1.
RefSeqiNP_001014151.1. NM_001014129.1.
UniGeneiRn.8908.

Genome annotation databases

EnsembliENSRNOT00000056725; ENSRNOP00000053566; ENSRNOG00000037478.
GeneIDi360828.
KEGGirno:360828.
UCSCiRGD:1310661. rat.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC088275 mRNA. Translation: AAH88275.1.
RefSeqiNP_001014151.1. NM_001014129.1.
UniGeneiRn.8908.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000053566.

PTM databases

iPTMnetiQ5I0I8.
PhosphoSiteiQ5I0I8.

Proteomic databases

PaxDbiQ5I0I8.
PRIDEiQ5I0I8.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSRNOT00000056725; ENSRNOP00000053566; ENSRNOG00000037478.
GeneIDi360828.
KEGGirno:360828.
UCSCiRGD:1310661. rat.

Organism-specific databases

CTDi79050.
RGDi1310661. Noc4l.

Phylogenomic databases

eggNOGiKOG2154. Eukaryota.
ENOG410YJPG. LUCA.
GeneTreeiENSGT00390000016776.
HOGENOMiHOG000158314.
HOVERGENiHBG060855.
InParanoidiQ5I0I8.
KOiK14771.
OMAiRRHPSCR.
OrthoDBiEOG091G07EE.
PhylomeDBiQ5I0I8.
TreeFamiTF105812.

Enzyme and pathway databases

ReactomeiR-RNO-6791226. Major pathway of rRNA processing in the nucleolus.

Miscellaneous databases

PROiQ5I0I8.

Gene expression databases

BgeeiENSRNOG00000037478.
GenevisibleiQ5I0I8. RN.

Family and domain databases

InterProiIPR016024. ARM-type_fold.
IPR005612. CCAAT-binding_factor.
IPR027193. Noc4.
[Graphical view]
PANTHERiPTHR12455:SF0. PTHR12455:SF0. 1 hit.
PfamiPF03914. CBF. 1 hit.
[Graphical view]
SUPFAMiSSF48371. SSF48371. 4 hits.
ProtoNetiSearch...

Entry informationi

Entry nameiNOC4L_RAT
AccessioniPrimary (citable) accession number: Q5I0I8
Entry historyi
Integrated into UniProtKB/Swiss-Prot: August 16, 2005
Last sequence update: February 15, 2005
Last modified: September 7, 2016
This is version 78 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.