Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

PHD finger protein 11

Gene

Phf11

Organism
Rattus norvegicus (Rat)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

Positive regulator of Th1-type cytokine gene expression.By similarity

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Zinc fingeri90 – 14556PHD-type; atypicalAdd
BLAST

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Activator

Keywords - Biological processi

Transcription, Transcription regulation

Keywords - Ligandi

Metal-binding, Zinc

Names & Taxonomyi

Protein namesi
Recommended name:
PHD finger protein 11
Gene namesi
Name:Phf11
OrganismiRattus norvegicus (Rat)
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Unplaced

Organism-specific databases

RGDi1310853. Phf11.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 336336PHD finger protein 11PRO_0000385016Add
BLAST

PTM databases

iPTMnetiQ5I0E2.

Interactioni

Subunit structurei

Interacts with BRCA1 and RELA.By similarity

Family & Domainsi

Sequence similaritiesi

Contains 1 PHD-type zinc finger.Curated

Zinc finger

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Zinc fingeri90 – 14556PHD-type; atypicalAdd
BLAST

Keywords - Domaini

Zinc-finger

Phylogenomic databases

HOGENOMiHOG000290637.
InParanoidiQ5I0E2.
PhylomeDBiQ5I0E2.

Family and domain databases

Gene3Di3.30.40.10. 1 hit.
InterProiIPR011011. Znf_FYVE_PHD.
IPR001965. Znf_PHD.
IPR013083. Znf_RING/FYVE/PHD.
[Graphical view]
SMARTiSM00249. PHD. 1 hit.
[Graphical view]
SUPFAMiSSF57903. SSF57903. 1 hit.

Sequencei

Sequence statusi: Complete.

Q5I0E2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAEETAPPCG PVSTGGSLSP EKMEKRTCAL CPDGHEWSVI YFAPSANIAA
60 70 80 90 100
HENCLLYSSG LVECGPHDPR NPARSFAVKS VKKEIWRGRR LKCSLCNKGG
110 120 130 140 150
ATVGCDLSSC RKSYHYVCAK KDHAIPQVDE DLGTYKIFCP EHPPQQEETT
160 170 180 190 200
ERADSPSVKK TGKKKSLSSG PPTEPKKMKF SRFKRLMKEE PHGHKDAAVK
210 220 230 240 250
APFLKKCLEA GLLTELFEQI LEKMDSIHGR FMDETASESD YEGIKTLLFD
260 270 280 290 300
CGLFGDILRK FQEVIKSKTC EYEERLNQMK QKLEALADLQ ENLCSFQECG
310 320 330
DLDPSGSTSG SLLPPEDHQC RCQESPEVQA GSGDSL
Length:336
Mass (Da):37,214
Last modified:February 15, 2005 - v1
Checksum:i208485B5FB1FA0D9
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC088433 mRNA. Translation: AAH88433.1.
RefSeqiNP_001019443.1. NM_001024272.1.
UniGeneiRn.213394.

Genome annotation databases

GeneIDi361051.
KEGGirno:361051.
UCSCiRGD:1310853. rat.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC088433 mRNA. Translation: AAH88433.1.
RefSeqiNP_001019443.1. NM_001024272.1.
UniGeneiRn.213394.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

PTM databases

iPTMnetiQ5I0E2.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi361051.
KEGGirno:361051.
UCSCiRGD:1310853. rat.

Organism-specific databases

CTDi51131.
RGDi1310853. Phf11.

Phylogenomic databases

HOGENOMiHOG000290637.
InParanoidiQ5I0E2.
PhylomeDBiQ5I0E2.

Miscellaneous databases

NextBioi675034.
PROiQ5I0E2.

Family and domain databases

Gene3Di3.30.40.10. 1 hit.
InterProiIPR011011. Znf_FYVE_PHD.
IPR001965. Znf_PHD.
IPR013083. Znf_RING/FYVE/PHD.
[Graphical view]
SMARTiSM00249. PHD. 1 hit.
[Graphical view]
SUPFAMiSSF57903. SSF57903. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: Lung.

Entry informationi

Entry nameiPHF11_RAT
AccessioniPrimary (citable) accession number: Q5I0E2
Entry historyi
Integrated into UniProtKB/Swiss-Prot: September 22, 2009
Last sequence update: February 15, 2005
Last modified: January 20, 2016
This is version 69 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.