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Protein

Glyoxalase domain-containing protein 4

Gene

Glod4

Organism
Rattus norvegicus (Rat)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Names & Taxonomyi

Protein namesi
Recommended name:
Glyoxalase domain-containing protein 4
Gene namesi
Name:Glod4
OrganismiRattus norvegicus (Rat)
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Chromosome 10

Organism-specific databases

RGDi1307010 Glod4

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Mitochondrion

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002803931 – 298Glyoxalase domain-containing protein 4Add BLAST298

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei109N6-succinyllysineBy similarity1
Modified residuei131PhosphoserineCombined sources1
Modified residuei273N6-succinyllysineBy similarity1

Keywords - PTMi

Phosphoprotein

Proteomic databases

PaxDbiQ5I0D1
PRIDEiQ5I0D1

PTM databases

iPTMnetiQ5I0D1
PhosphoSitePlusiQ5I0D1
SwissPalmiQ5I0D1

Expressioni

Gene expression databases

BgeeiENSRNOG00000007788
GenevisibleiQ5I0D1 RN

Interactioni

Subunit structurei

Interacts with NUDT9.By similarity

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000010386

Structurei

3D structure databases

ProteinModelPortaliQ5I0D1
SMRiQ5I0D1
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini5 – 130VOC 1PROSITE-ProRule annotationAdd BLAST126
Domaini137 – 258VOC 2PROSITE-ProRule annotationAdd BLAST122

Sequence similaritiesi

Belongs to the glyoxalase I family.Curated

Keywords - Domaini

Repeat

Phylogenomic databases

eggNOGiENOG410IRT7 Eukaryota
ENOG410XP3J LUCA
GeneTreeiENSGT00390000012340
HOVERGENiHBG056038
InParanoidiQ5I0D1
OMAiCEAACNG
OrthoDBiEOG091G0EHY
PhylomeDBiQ5I0D1

Family and domain databases

Gene3Di3.10.180.10, 2 hits
InterProiView protein in InterPro
IPR029068 Glyas_Bleomycin-R_OHBP_Dase
IPR037523 VOC
SUPFAMiSSF54593 SSF54593, 1 hit
PROSITEiView protein in PROSITE
PS51819 VOC, 2 hits

Sequencei

Sequence statusi: Complete.

Q5I0D1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVTRRALHFV FKVGNRFQTV HFFRDVLGMQ VLRHEEFEEG CKAACNGPYD
60 70 80 90 100
GKWSKTMVGF GPEDDHFVAE LTYNYGIGDY KLGNDFMGLT LASSQAVSNA
110 120 130 140 150
RRLEWPLSKV AEGVFETEAP GGYKFYLQDR SPSQSDPVLK VTLAVSDLQK
160 170 180 190 200
SLNYWSNLLG MKIYEQDEEK KWALLGYADD QCKLELQGIQ GAVDHSAAFG
210 220 230 240 250
RIAFSCPQKE LPDLEDLMKR ESQSILTPLV SLDTPGKATV QVVILADPDG
260 270 280 290
HEICFVGDEA FRELSKMDPK GSKLLDDAMA ADKSDEWFAT RNKPKASG
Length:298
Mass (Da):33,268
Last modified:February 15, 2005 - v1
Checksum:i17D91F9093EBDA80
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC088458 mRNA Translation: AAH88458.1
RefSeqiNP_001014249.1, NM_001014227.1
UniGeneiRn.24630

Genome annotation databases

EnsembliENSRNOT00000010386; ENSRNOP00000010386; ENSRNOG00000007788
GeneIDi363644
KEGGirno:363644

Similar proteinsi

Entry informationi

Entry nameiGLOD4_RAT
AccessioniPrimary (citable) accession number: Q5I0D1
Entry historyiIntegrated into UniProtKB/Swiss-Prot: March 20, 2007
Last sequence update: February 15, 2005
Last modified: May 23, 2018
This is version 69 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Direct protein sequencing, Reference proteome

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