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Protein

Glyoxalase domain-containing protein 4

Gene

Glod4

Organism
Rattus norvegicus (Rat)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Names & Taxonomyi

Protein namesi
Recommended name:
Glyoxalase domain-containing protein 4
Gene namesi
Name:Glod4
OrganismiRattus norvegicus (Rat)
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus
ProteomesiUP000002494 Componenti: Chromosome 10

Organism-specific databases

RGDi1307010. Glod4.

Subcellular locationi

Mitochondrion By similarity

GO - Cellular componenti

  1. extracellular vesicular exosome Source: Ensembl
  2. mitochondrion Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Mitochondrion

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 298298Glyoxalase domain-containing protein 4PRO_0000280393Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei109 – 1091N6-succinyllysineBy similarity
Modified residuei273 – 2731N6-succinyllysineBy similarity

Proteomic databases

PRIDEiQ5I0D1.

Expressioni

Gene expression databases

GenevestigatoriQ5I0D1.

Interactioni

Subunit structurei

Interacts with NUDT9.By similarity

Structurei

3D structure databases

ProteinModelPortaliQ5I0D1.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the glyoxalase I family.Curated

Phylogenomic databases

GeneTreeiENSGT00390000012340.
HOVERGENiHBG056038.
InParanoidiQ5I0D1.
OMAiQGCDAAC.
OrthoDBiEOG769ZK8.
PhylomeDBiQ5I0D1.

Family and domain databases

Gene3Di3.10.180.10. 2 hits.
InterProiIPR029068. Glyas_Bleomycin-R_OHBP_Dase.
IPR025870. Glyoxalase-like_dom.
[Graphical view]
PfamiPF12681. Glyoxalase_2. 1 hit.
[Graphical view]
SUPFAMiSSF54593. SSF54593. 1 hit.

Sequencei

Sequence statusi: Complete.

Q5I0D1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVTRRALHFV FKVGNRFQTV HFFRDVLGMQ VLRHEEFEEG CKAACNGPYD
60 70 80 90 100
GKWSKTMVGF GPEDDHFVAE LTYNYGIGDY KLGNDFMGLT LASSQAVSNA
110 120 130 140 150
RRLEWPLSKV AEGVFETEAP GGYKFYLQDR SPSQSDPVLK VTLAVSDLQK
160 170 180 190 200
SLNYWSNLLG MKIYEQDEEK KWALLGYADD QCKLELQGIQ GAVDHSAAFG
210 220 230 240 250
RIAFSCPQKE LPDLEDLMKR ESQSILTPLV SLDTPGKATV QVVILADPDG
260 270 280 290
HEICFVGDEA FRELSKMDPK GSKLLDDAMA ADKSDEWFAT RNKPKASG
Length:298
Mass (Da):33,268
Last modified:February 15, 2005 - v1
Checksum:i17D91F9093EBDA80
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC088458 mRNA. Translation: AAH88458.1.
RefSeqiNP_001014249.1. NM_001014227.1.
UniGeneiRn.24630.

Genome annotation databases

EnsembliENSRNOT00000010386; ENSRNOP00000010386; ENSRNOG00000007788.
GeneIDi363644.
KEGGirno:363644.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC088458 mRNA. Translation: AAH88458.1.
RefSeqiNP_001014249.1. NM_001014227.1.
UniGeneiRn.24630.

3D structure databases

ProteinModelPortaliQ5I0D1.
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

PRIDEiQ5I0D1.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSRNOT00000010386; ENSRNOP00000010386; ENSRNOG00000007788.
GeneIDi363644.
KEGGirno:363644.

Organism-specific databases

CTDi51031.
RGDi1307010. Glod4.

Phylogenomic databases

GeneTreeiENSGT00390000012340.
HOVERGENiHBG056038.
InParanoidiQ5I0D1.
OMAiQGCDAAC.
OrthoDBiEOG769ZK8.
PhylomeDBiQ5I0D1.

Miscellaneous databases

NextBioi683871.

Gene expression databases

GenevestigatoriQ5I0D1.

Family and domain databases

Gene3Di3.10.180.10. 2 hits.
InterProiIPR029068. Glyas_Bleomycin-R_OHBP_Dase.
IPR025870. Glyoxalase-like_dom.
[Graphical view]
PfamiPF12681. Glyoxalase_2. 1 hit.
[Graphical view]
SUPFAMiSSF54593. SSF54593. 1 hit.
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: Kidney.
  2. Lubec G., Kang S.U.
    Submitted (JUN-2007) to UniProtKB
    Cited for: PROTEIN SEQUENCE OF 131-140, IDENTIFICATION BY MASS SPECTROMETRY.
    Strain: Sprague-Dawley.
    Tissue: Brain.

Entry informationi

Entry nameiGLOD4_RAT
AccessioniPrimary (citable) accession number: Q5I0D1
Entry historyi
Integrated into UniProtKB/Swiss-Prot: March 20, 2007
Last sequence update: February 15, 2005
Last modified: March 4, 2015
This is version 49 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Direct protein sequencing, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.