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Q5I0D1

- GLOD4_RAT

UniProt

Q5I0D1 - GLOD4_RAT

Protein

Glyoxalase domain-containing protein 4

Gene

Glod4

Organism
Rattus norvegicus (Rat)
Status
Reviewed - Annotation score: 2 out of 5- Experimental evidence at protein leveli
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    • History
      Entry version 46 (01 Oct 2014)
      Sequence version 1 (15 Feb 2005)
      Previous versions | rss
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    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Glyoxalase domain-containing protein 4
    Gene namesi
    Name:Glod4
    OrganismiRattus norvegicus (Rat)
    Taxonomic identifieri10116 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus
    ProteomesiUP000002494: Chromosome 10

    Organism-specific databases

    RGDi1307010. Glod4.

    Subcellular locationi

    Mitochondrion By similarity

    GO - Cellular componenti

    1. mitochondrion Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Mitochondrion

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 298298Glyoxalase domain-containing protein 4PRO_0000280393Add
    BLAST

    Amino acid modifications

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Modified residuei109 – 1091N6-succinyllysineBy similarity
    Modified residuei273 – 2731N6-succinyllysineBy similarity

    Proteomic databases

    PRIDEiQ5I0D1.

    Expressioni

    Gene expression databases

    GenevestigatoriQ5I0D1.

    Interactioni

    Subunit structurei

    Interacts with NUDT9.By similarity

    Structurei

    3D structure databases

    ProteinModelPortaliQ5I0D1.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the glyoxalase I family.Curated

    Phylogenomic databases

    GeneTreeiENSGT00390000012340.
    HOVERGENiHBG056038.
    OMAiGQCELEI.
    OrthoDBiEOG769ZK8.
    PhylomeDBiQ5I0D1.

    Family and domain databases

    Gene3Di3.10.180.10. 2 hits.
    InterProiIPR029068. Glyas_Bleomycin-R_OHBP_Dase.
    IPR025870. Glyoxalase-like_dom.
    [Graphical view]
    PfamiPF12681. Glyoxalase_2. 1 hit.
    [Graphical view]
    SUPFAMiSSF54593. SSF54593. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    Q5I0D1-1 [UniParc]FASTAAdd to Basket

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    MVTRRALHFV FKVGNRFQTV HFFRDVLGMQ VLRHEEFEEG CKAACNGPYD    50
    GKWSKTMVGF GPEDDHFVAE LTYNYGIGDY KLGNDFMGLT LASSQAVSNA 100
    RRLEWPLSKV AEGVFETEAP GGYKFYLQDR SPSQSDPVLK VTLAVSDLQK 150
    SLNYWSNLLG MKIYEQDEEK KWALLGYADD QCKLELQGIQ GAVDHSAAFG 200
    RIAFSCPQKE LPDLEDLMKR ESQSILTPLV SLDTPGKATV QVVILADPDG 250
    HEICFVGDEA FRELSKMDPK GSKLLDDAMA ADKSDEWFAT RNKPKASG 298
    Length:298
    Mass (Da):33,268
    Last modified:February 15, 2005 - v1
    Checksum:i17D91F9093EBDA80
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    BC088458 mRNA. Translation: AAH88458.1.
    RefSeqiNP_001014249.1. NM_001014227.1.
    UniGeneiRn.24630.

    Genome annotation databases

    EnsembliENSRNOT00000010386; ENSRNOP00000010386; ENSRNOG00000007788.
    GeneIDi363644.
    KEGGirno:363644.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    BC088458 mRNA. Translation: AAH88458.1 .
    RefSeqi NP_001014249.1. NM_001014227.1.
    UniGenei Rn.24630.

    3D structure databases

    ProteinModelPortali Q5I0D1.
    ModBasei Search...
    MobiDBi Search...

    Proteomic databases

    PRIDEi Q5I0D1.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENSRNOT00000010386 ; ENSRNOP00000010386 ; ENSRNOG00000007788 .
    GeneIDi 363644.
    KEGGi rno:363644.

    Organism-specific databases

    CTDi 51031.
    RGDi 1307010. Glod4.

    Phylogenomic databases

    GeneTreei ENSGT00390000012340.
    HOVERGENi HBG056038.
    OMAi GQCELEI.
    OrthoDBi EOG769ZK8.
    PhylomeDBi Q5I0D1.

    Miscellaneous databases

    NextBioi 683871.

    Gene expression databases

    Genevestigatori Q5I0D1.

    Family and domain databases

    Gene3Di 3.10.180.10. 2 hits.
    InterProi IPR029068. Glyas_Bleomycin-R_OHBP_Dase.
    IPR025870. Glyoxalase-like_dom.
    [Graphical view ]
    Pfami PF12681. Glyoxalase_2. 1 hit.
    [Graphical view ]
    SUPFAMi SSF54593. SSF54593. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
      Tissue: Kidney.
    2. Lubec G., Kang S.U.
      Submitted (JUL-2007) to UniProtKB
      Cited for: PROTEIN SEQUENCE OF 131-140, IDENTIFICATION BY MASS SPECTROMETRY.
      Strain: Sprague-Dawley.
      Tissue: Brain.

    Entry informationi

    Entry nameiGLOD4_RAT
    AccessioniPrimary (citable) accession number: Q5I0D1
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: March 20, 2007
    Last sequence update: February 15, 2005
    Last modified: October 1, 2014
    This is version 46 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programChordata Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Direct protein sequencing, Reference proteome

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3