Q5I037 (Q5I037_MOUSE) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
E2f8 protein EMBL AAH88748.1

Gene names

Name:

E2f8 MGI 1922038

Organism

Mus musculus (Mouse) EMBL AAH88748.1

Taxonomic identifier

10090 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Glires › Rodentia › Sciurognathi › Muroidea › Muridae › Murinae › Mus › Mus

Protein attributes

Sequence length	404 AA.
Sequence status	Fragment.
Protein existence	Evidence at transcript level

General annotation (Comments)

Subcellular location	Nucleus By similarity RuleBase RU003796.
Sequence similarities	Belongs to the E2F/DP family. RuleBase RU003796

Ontologies

Keywords
Biological process	Transcription Transcription regulation RuleBase RU003796
Cellular component	Nucleus RuleBase RU003796
Ligand	DNA-binding RuleBase RU003796
Gene Ontology (GO)
Biological_process	cell proliferation Inferred from direct assay PubMed 15722552. Source: MGI transcription, DNA-dependent Inferred from electronic annotation. Source: UniProtKB-KW
Cellular_component	nucleus Inferred from direct assay PubMed 15722552. Source: MGI transcription factor complex Inferred from electronic annotation. Source: InterPro
Molecular_function	DNA binding Inferred from direct assay PubMed 15722552. Source: MGI sequence-specific DNA binding transcription factor activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Experimental info
	Non-terminal residue	1	1	EMBL AAH88748.1

Sequences

	Sequence		Length	Mass (Da)
	Q5I037 [UniParc]. Last modified February 15, 2005. Version 1. Checksum: 771C6A53DC0C7CE5	FASTA	404	43,299
	10 20 30 40 50 60 PQIVSLEIAA KILIGEDHVE DLDKSKYKTE IRRLYDIANV LSSLDLIKKV HVTEERGRKP 70 80 90 100 110 120 AFKWTGPEIS PNNSGSSPIM PLPASLEAEQ SAKENCVKNL FSTRGKPSFT RHPSLIKLVK 130 140 150 160 170 180 SIENDRRKIS SAPSSPVKSN KAESSQNSPP VPNKMAQLAA ICKMQLEEQS SEPRKKVKVN 190 200 210 220 230 240 LARSGHYKPL APLDPTVNTE LELLTPSLIQ PLGVVPLIPV ASSELTAVNF PPFHVTPLKL 250 260 270 280 290 300 MVSPTSMAAV PVGNSPALNS GHPAPAQNPS SAIVNFTLQH LGLISPGVQM SASPRPGAGT 310 320 330 340 350 360 VPVSPRVEAD NLSSRQRRAT NHDSPVLGQS QLNGQPVAGT GAQQPVPVTP KGSQLVAENF 370 380 390 400 FRTPGGPTKP TSSPYTDFDG ANKTSFGTLF VPQRKLEVST EDIH

References

[1]

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." The MGC Project Team Gerhard D.S., Wagner L., Feingold E.A., Shenmen C.M., Grouse L.H., Schuler G., Klein S.L., Old S., Rasooly R., Good P., Guyer M., Peck A.M., Derge J.G., Lipman D., Collins F.S., Jang W., Sherry S., Feolo M. , Misquitta L., Lee E., Rotmistrovsky K., Greenhut S.F., Schaefer C.F., Buetow K., Bonner T.I., Haussler D., Kent J., Kiekhaus M., Furey T., Brent M., Prange C., Schreiber K., Shapiro N., Bhat N.K., Hopkins R.F., Hsie F., Driscoll T., Soares M.B., Casavant T.L., Scheetz T.E., Brown-stein M.J., Usdin T.B., Toshiyuki S., Carninci P., Piao Y., Dudekula D.B., Ko M.S., Kawakami K., Suzuki Y., Sugano S., Gruber C.E., Smith M.R., Simmons B., Moore T., Waterman R., Johnson S.L., Ruan Y., Wei C.L., Mathavan S., Gunaratne P.H., Wu J., Garcia A.M., Hulyk S.W., Fuh E., Yuan Y., Sneed A., Kowis C., Hodgson A., Muzny D.M., McPherson J., Gibbs R.A., Fahey J., Helton E., Ketteman M., Madan A., Rodrigues S., Sanchez A., Whiting M., Madari A., Young A.C., Wetherby K.D., Granite S.J., Kwong P.N., Brinkley C.P., Pearson R.L., Bouffard G.G., Blakesly R.W., Green E.D., Dickson M.C., Rodriguez A.C., Grimwood J., Schmutz J., Myers R.M., Butterfield Y.S., Griffith M., Griffith O.L., Krzywinski M.I., Liao N., Morin R., Morrin R., Palmquist D., Petrescu A.S., Skalska U., Smailus D.E., Stott J.M., Schnerch A., Schein J.E., Jones S.J., Holt R.A., Baross A., Marra M.A., Clifton S., Makowski K.A., Bosak S., Malek J. Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. Tissue: Embryonic stem cell EMBL AAH88748.1.

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Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	BC088748 mRNA. Translation: AAH88748.1.
IPI	IPI00553437.
UniGene	Mm.240566.
3D structure databases
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Organism-specific databases
MGI	MGI:1922038. E2f8.
Phylogenomic databases
HOGENOM	HOG000207196.
Gene expression databases
Genevestigator	Q5I037.
Family and domain databases
Gene3D	1.10.10.10. 1 hit.
InterPro	IPR015633. E2F. IPR003316. E2F_TDP. IPR011991. WHTH_DNA-bd_dom. [Graphical view]
PANTHER	PTHR12081. PTHR12081. 1 hit.
Pfam	PF02319. E2F_TDP. 1 hit. [Graphical view]
ProtoNet	Search...
Other
ChiTaRS	E2F8. mouse.
SOURCE	Search...

Entry information

Entry name

Q5I037_MOUSE

Accession

Primary (citable) accession number: Q5I037

Entry history

Integrated into UniProtKB/TrEMBL:	February 15, 2005
Last sequence update:	February 15, 2005
Last modified:	May 1, 2013
This is version 53 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)