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Protein

V-type proton ATPase subunit G

Gene

Atp6v1g1

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

Catalytic subunit of the peripheral V1 complex of vacuolar ATPase (V-ATPase). V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.UniRule annotation

GO - Molecular functioni

Keywordsi

Biological processHydrogen ion transportUniRule annotation, Ion transport, Transport

Names & Taxonomyi

Protein namesi
Recommended name:
V-type proton ATPase subunit GUniRule annotation
Gene namesi
Name:Atp6v1g1Imported
Synonyms:Atp6g1Imported
ORF Names:mCG_20078Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus

Organism-specific databases

MGIiMGI:1913540. Atp6v1g1.

Subcellular locationi

GO - Cellular componenti

Expressioni

Gene expression databases

BgeeiENSMUSG00000039105.
ExpressionAtlasiQ5HZY7. baseline and differential.

Interactioni

Subunit structurei

V-ATPase is a heteromultimeric enzyme composed of a peripheral catalytic V1 complex (components A to H) attached to an integral membrane V0 proton pore complex.UniRule annotation

GO - Molecular functioni

Structurei

3D structure databases

SMRiQ5HZY7.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili8 – 57Sequence analysisAdd BLAST50

Sequence similaritiesi

Belongs to the V-ATPase G subunit family.UniRule annotation

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

eggNOGiKOG1772. Eukaryota.
ENOG4111XX0. LUCA.
HOVERGENiHBG057827.
KOiK02152.
OMAiEFHANYR.
OrthoDBiEOG091G0XIZ.

Family and domain databases

InterProiView protein in InterPro
IPR005124. V-ATPase_G.
PANTHERiPTHR12713. PTHR12713. 1 hit.
TIGRFAMsiTIGR01147. V_ATP_synt_G. 1 hit.

Sequencei

Sequence statusi: Complete.

Q5HZY7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MASQSQGIQQ LLQAEKRAAE KVSEARKRKN RRLKQAKEEA QAEIEQYRLQ
60 70 80 90 100
REKEFKAKEA AALGSHGSCS SEVEKETREK MTVLQNYFEQ NRDEVLDNLL
110
AFVCDIRPEI HENYRING
Length:118
Mass (Da):13,724
Last modified:February 5, 2008 - v1
Checksum:i1FC54025CFCFD951
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC088836 mRNA. Translation: AAH88836.1.
AB076406 mRNA. Translation: BAC10289.1.
AK081611 mRNA. Translation: BAC38271.1.
AK088712 mRNA. Translation: BAC40520.1.
AK159558 mRNA. Translation: BAE35183.1.
AK168972 mRNA. Translation: BAE40775.1.
CH466527 Genomic DNA. Translation: EDL31101.1.
RefSeqiNP_077135.1. NM_024173.2.
UniGeneiMm.371615.

Genome annotation databases

GeneIDi66290.
KEGGimmu:66290.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.

Entry informationi

Entry nameiQ5HZY7_MOUSE
AccessioniPrimary (citable) accession number: Q5HZY7
Entry historyiIntegrated into UniProtKB/TrEMBL: February 5, 2008
Last sequence update: February 5, 2008
Last modified: July 5, 2017
This is version 90 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)