Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Q5HZV5

- CNPY3_XENTR

UniProt

Q5HZV5 - CNPY3_XENTR

Protein

Protein canopy homolog 3

Gene

cnpy3

Organism
Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)
Status
Reviewed - Annotation score: 2 out of 5- Experimental evidence at transcript leveli
    • BLAST
    • Align
    • Format
    • Add to basket
    • History
      Entry version 28 (01 Oct 2014)
      Sequence version 2 (15 Jan 2008)
      Previous versions | rss
    • Help video
    • Feedback
    • Comment

    Functioni

    Toll-like receptor (TLR)-specific co-chaperone for HSP90B1. Required for proper TLR folding and hence controls TLR exit from the endoplasmic reticulum. Consequently, required for immune responses By similarity.By similarity

    GO - Biological processi

    1. innate immune response Source: UniProtKB-KW

    Keywords - Molecular functioni

    Chaperone

    Keywords - Biological processi

    Immunity, Innate immunity

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Protein canopy homolog 3
    Gene namesi
    Name:cnpy3
    OrganismiXenopus tropicalis (Western clawed frog) (Silurana tropicalis)
    Taxonomic identifieri8364 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiAmphibiaBatrachiaAnuraPipoideaPipidaeXenopodinaeXenopusSilurana
    ProteomesiUP000008143: Unplaced

    Organism-specific databases

    XenbaseiXB-GENE-6455266. cnpy3.

    Subcellular locationi

    Endoplasmic reticulum By similarity

    GO - Cellular componenti

    1. endoplasmic reticulum Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Endoplasmic reticulum

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Signal peptidei1 – 1919Sequence AnalysisAdd
    BLAST
    Chaini20 – 242223Protein canopy homolog 3PRO_0000313785Add
    BLAST

    Amino acid modifications

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Disulfide bondi28 ↔ 187By similarity
    Disulfide bondi31 ↔ 175By similarity
    Disulfide bondi85 ↔ 147By similarity

    Keywords - PTMi

    Disulfide bond

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Domaini26 – 235210Saposin B-typeAdd
    BLAST

    Sequence similaritiesi

    Belongs to the canopy family.Curated
    Contains 1 saposin B-type domain.Curated

    Keywords - Domaini

    Signal

    Phylogenomic databases

    HOVERGENiHBG107736.

    Family and domain databases

    InterProiIPR021852. DUF3456.
    [Graphical view]
    PfamiPF11938. DUF3456. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Sequence processingi: The displayed sequence is further processed into a mature form.

    Q5HZV5-1 [UniParc]FASTAAdd to Basket

    « Hide

    MWLLLLLPLW GGCAEPGDSE WVNLPSKCEV CKYVALELKS SFDETSRTRE    50
    LIDTRYGFLE DDKKAKKIKY TNSDIRLIEV TEGLCSRLLE YNLHKERSGS 100
    NRFAKGMSET FQTLHHLVHK GVKVVMDIPY ELWNETSAEV ADMKKQCDVM 150
    METYEDVIED WYRHHQEADL TEFLCARHVL RGQDQSCLEE HWDSRKGDTG 200
    PSTGTKKQKK QGEKKNKSKK ENSGPEEERR QMEQPTAAKE EL 242
    Length:242
    Mass (Da):28,120
    Last modified:January 15, 2008 - v2
    Checksum:i985D24FBD48EC41E
    GO

    Sequence cautioni

    The sequence AAH88872.1 differs from that shown. Reason: Erroneous initiation.

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    BC088872 mRNA. Translation: AAH88872.1. Different initiation.
    UniGeneiStr.22034.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    BC088872 mRNA. Translation: AAH88872.1 . Different initiation.
    UniGenei Str.22034.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Organism-specific databases

    Xenbasei XB-GENE-6455266. cnpy3.

    Phylogenomic databases

    HOVERGENi HBG107736.

    Family and domain databases

    InterProi IPR021852. DUF3456.
    [Graphical view ]
    Pfami PF11938. DUF3456. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. NIH - Xenopus Gene Collection (XGC) project
      Submitted (JAN-2005) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].

    Entry informationi

    Entry nameiCNPY3_XENTR
    AccessioniPrimary (citable) accession number: Q5HZV5
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: January 15, 2008
    Last sequence update: January 15, 2008
    Last modified: October 1, 2014
    This is version 28 of the entry and version 2 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programChordata Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3