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Protein

Solute carrier family 25 member 51

Gene

Slc25a51

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Biological processTransport

Names & Taxonomyi

Protein namesi
Recommended name:
Solute carrier family 25 member 51
Alternative name(s):
Mitochondrial carrier triple repeat protein 1
Gene namesi
Name:Slc25a51
Synonyms:Mcart1
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 4

Organism-specific databases

MGIiMGI:2684984 Slc25a51

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei36 – 56Helical; Name=1Sequence analysisAdd BLAST21
Transmembranei85 – 105Helical; Name=2Sequence analysisAdd BLAST21
Transmembranei119 – 139Helical; Name=3Sequence analysisAdd BLAST21
Transmembranei180 – 200Helical; Name=4Sequence analysisAdd BLAST21
Transmembranei216 – 236Helical; Name=5Sequence analysisAdd BLAST21
Transmembranei269 – 290Helical; Name=6Sequence analysisAdd BLAST22

Keywords - Cellular componenti

Membrane, Mitochondrion, Mitochondrion inner membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000907121 – 298Solute carrier family 25 member 51Add BLAST298

Proteomic databases

EPDiQ5HZI9
MaxQBiQ5HZI9
PaxDbiQ5HZI9
PeptideAtlasiQ5HZI9
PRIDEiQ5HZI9

PTM databases

iPTMnetiQ5HZI9
PhosphoSitePlusiQ5HZI9

Expressioni

Gene expression databases

BgeeiENSMUSG00000045973
CleanExiMM_MCART1
ExpressionAtlasiQ5HZI9 baseline and differential
GenevisibleiQ5HZI9 MM

Interactioni

Protein-protein interaction databases

IntActiQ5HZI9, 1 interactor
MINTiQ5HZI9
STRINGi10090.ENSMUSP00000112044

Structurei

3D structure databases

ProteinModelPortaliQ5HZI9
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Repeati28 – 108Solcar 1Add BLAST81
Repeati117 – 201Solcar 2Add BLAST85
Repeati214 – 297Solcar 3Add BLAST84

Sequence similaritiesi

Keywords - Domaini

Repeat, Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiKOG1519 Eukaryota
ENOG410XNWT LUCA
GeneTreeiENSGT00730000110930
HOGENOMiHOG000233158
HOVERGENiHBG052423
InParanoidiQ5HZI9

Family and domain databases

Gene3Di1.50.40.10, 1 hit
InterProiView protein in InterPro
IPR018108 Mitochondrial_sb/sol_carrier
IPR023395 Mt_carrier_dom_sf
PfamiView protein in Pfam
PF00153 Mito_carr, 3 hits
SUPFAMiSSF103506 SSF103506, 1 hit
PROSITEiView protein in PROSITE
PS50920 SOLCAR, 3 hits

Sequencei

Sequence statusi: Complete.

Q5HZI9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MMDSEAHEKR PPMLTSSNQD LSPHIAGVGD MKHYLCGYCA AFNNVAITYP
60 70 80 90 100
VQKILFRQQL YGIKTRDAVL QLRKDGFRNL YRGILPPLMQ KTTTLALMFG
110 120 130 140 150
LYEDLSRLLH KHVSSAPEFA TRSVAALLAG TTEAILTPFE RVQTLLQDHK
160 170 180 190 200
HHDKFTNTYQ AFRALRCHGI AEYYRGMVPI LFRNGFGNVL FFGLRGPIKE
210 220 230 240 250
SLPTATTYSA HLVNDFICGG VLGAVLGFLS FPINVVKARI QSQIGGPFLS
260 270 280 290
LPMVFKTIWI ERDRKLINLF RGAHLNYHRS LISWGIINAT YEFLLKIV
Length:298
Mass (Da):33,689
Last modified:February 15, 2005 - v1
Checksum:i28DF1E7411847065
GO

Sequence cautioni

The sequence BAE27432 differs from that shown. Reason: Erroneous initiation. Translation N-terminally shortened.Curated
The sequence BAE29497 differs from that shown. Reason: Erroneous initiation. Translation N-terminally shortened.Curated
The sequence BAE30612 differs from that shown. Reason: Erroneous initiation. Translation N-terminally shortened.Curated
The sequence BAE31003 differs from that shown. Reason: Erroneous initiation. Translation N-terminally shortened.Curated
The sequence BAE33610 differs from that shown. Reason: Erroneous initiation. Translation N-terminally shortened.Curated
The sequence BAE38106 differs from that shown. Reason: Erroneous initiation. Translation N-terminally shortened.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti294 – 298LLKIV → FVKDCMMKSLCEMLFSSN in BAE33610 (PubMed:16141072).Curated5

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK146788 mRNA Translation: BAE27432.1 Different initiation.
AK150362 mRNA Translation: BAE29497.1 Different initiation.
AK151688 mRNA Translation: BAE30612.1 Different initiation.
AK152171 mRNA Translation: BAE31003.1 Different initiation.
AK156168 mRNA Translation: BAE33610.1 Different initiation.
AK165253 mRNA Translation: BAE38106.1 Different initiation.
BC089000 mRNA Translation: AAH89000.1
CCDSiCCDS18137.1
RefSeqiNP_001009949.3, NM_001009949.3
XP_006537898.1, XM_006537835.3
XP_017175615.1, XM_017320126.1
UniGeneiMm.260210

Genome annotation databases

EnsembliENSMUST00000116341; ENSMUSP00000112044; ENSMUSG00000045973
ENSMUST00000132815; ENSMUSP00000134132; ENSMUSG00000045973
GeneIDi230125
KEGGimmu:230125
UCSCiuc008ssr.2 mouse

Similar proteinsi

Entry informationi

Entry nameiS2551_MOUSE
AccessioniPrimary (citable) accession number: Q5HZI9
Secondary accession number(s): Q3U190, Q3UCW5
Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 10, 2005
Last sequence update: February 15, 2005
Last modified: May 23, 2018
This is version 100 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

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