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Protein

Solute carrier family 25 member 51

Gene

Slc25a51

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Transport

Names & Taxonomyi

Protein namesi
Recommended name:
Solute carrier family 25 member 51
Alternative name(s):
Mitochondrial carrier triple repeat protein 1
Gene namesi
Name:Slc25a51
Synonyms:Mcart1
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 4

Organism-specific databases

MGIiMGI:2684984. Slc25a51.

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei36 – 5621Helical; Name=1Sequence analysisAdd
BLAST
Transmembranei85 – 10521Helical; Name=2Sequence analysisAdd
BLAST
Transmembranei119 – 13921Helical; Name=3Sequence analysisAdd
BLAST
Transmembranei180 – 20021Helical; Name=4Sequence analysisAdd
BLAST
Transmembranei216 – 23621Helical; Name=5Sequence analysisAdd
BLAST
Transmembranei269 – 29022Helical; Name=6Sequence analysisAdd
BLAST

GO - Cellular componenti

  • integral component of membrane Source: UniProtKB-KW
  • mitochondrial inner membrane Source: UniProtKB-SubCell
  • mitochondrion Source: MGI
Complete GO annotation...

Keywords - Cellular componenti

Membrane, Mitochondrion, Mitochondrion inner membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 298298Solute carrier family 25 member 51PRO_0000090712Add
BLAST

Proteomic databases

EPDiQ5HZI9.
MaxQBiQ5HZI9.
PaxDbiQ5HZI9.
PeptideAtlasiQ5HZI9.
PRIDEiQ5HZI9.

PTM databases

iPTMnetiQ5HZI9.
PhosphoSiteiQ5HZI9.

Expressioni

Gene expression databases

BgeeiENSMUSG00000045973.
CleanExiMM_MCART1.
ExpressionAtlasiQ5HZI9. baseline and differential.
GenevisibleiQ5HZI9. MM.

Interactioni

Protein-protein interaction databases

IntActiQ5HZI9. 1 interaction.
MINTiMINT-4653162.
STRINGi10090.ENSMUSP00000112044.

Structurei

3D structure databases

ProteinModelPortaliQ5HZI9.
SMRiQ5HZI9. Positions 29-298.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Repeati28 – 10881Solcar 1Add
BLAST
Repeati117 – 20185Solcar 2Add
BLAST
Repeati214 – 29784Solcar 3Add
BLAST

Sequence similaritiesi

Contains 3 Solcar repeats.PROSITE-ProRule annotation

Keywords - Domaini

Repeat, Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiKOG1519. Eukaryota.
ENOG410XNWT. LUCA.
GeneTreeiENSGT00730000110930.
HOGENOMiHOG000233158.
HOVERGENiHBG052423.
InParanoidiQ5HZI9.

Family and domain databases

Gene3Di1.50.40.10. 1 hit.
InterProiIPR018108. Mitochondrial_sb/sol_carrier.
IPR023395. Mt_carrier_dom.
[Graphical view]
PfamiPF00153. Mito_carr. 3 hits.
[Graphical view]
SUPFAMiSSF103506. SSF103506. 1 hit.
PROSITEiPS50920. SOLCAR. 3 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q5HZI9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MMDSEAHEKR PPMLTSSNQD LSPHIAGVGD MKHYLCGYCA AFNNVAITYP
60 70 80 90 100
VQKILFRQQL YGIKTRDAVL QLRKDGFRNL YRGILPPLMQ KTTTLALMFG
110 120 130 140 150
LYEDLSRLLH KHVSSAPEFA TRSVAALLAG TTEAILTPFE RVQTLLQDHK
160 170 180 190 200
HHDKFTNTYQ AFRALRCHGI AEYYRGMVPI LFRNGFGNVL FFGLRGPIKE
210 220 230 240 250
SLPTATTYSA HLVNDFICGG VLGAVLGFLS FPINVVKARI QSQIGGPFLS
260 270 280 290
LPMVFKTIWI ERDRKLINLF RGAHLNYHRS LISWGIINAT YEFLLKIV
Length:298
Mass (Da):33,689
Last modified:February 15, 2005 - v1
Checksum:i28DF1E7411847065
GO

Sequence cautioni

The sequence BAE27432 differs from that shown. Reason: Erroneous initiation. Translation N-terminally shortened.Curated
The sequence BAE29497 differs from that shown. Reason: Erroneous initiation. Translation N-terminally shortened.Curated
The sequence BAE30612 differs from that shown. Reason: Erroneous initiation. Translation N-terminally shortened.Curated
The sequence BAE31003 differs from that shown. Reason: Erroneous initiation. Translation N-terminally shortened.Curated
The sequence BAE33610 differs from that shown. Reason: Erroneous initiation. Translation N-terminally shortened.Curated
The sequence BAE38106 differs from that shown. Reason: Erroneous initiation. Translation N-terminally shortened.Curated

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti294 – 2985LLKIV → FVKDCMMKSLCEMLFSSN in BAE33610 (PubMed:16141072).Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK146788 mRNA. Translation: BAE27432.1. Different initiation.
AK150362 mRNA. Translation: BAE29497.1. Different initiation.
AK151688 mRNA. Translation: BAE30612.1. Different initiation.
AK152171 mRNA. Translation: BAE31003.1. Different initiation.
AK156168 mRNA. Translation: BAE33610.1. Different initiation.
AK165253 mRNA. Translation: BAE38106.1. Different initiation.
BC089000 mRNA. Translation: AAH89000.1.
CCDSiCCDS18137.1.
RefSeqiNP_001009949.3. NM_001009949.3.
XP_006537898.1. XM_006537835.2.
XP_011248301.1. XM_011249999.1.
UniGeneiMm.260210.

Genome annotation databases

EnsembliENSMUST00000116341; ENSMUSP00000112044; ENSMUSG00000045973.
ENSMUST00000132815; ENSMUSP00000134132; ENSMUSG00000045973.
GeneIDi230125.
KEGGimmu:230125.
UCSCiuc008ssr.2. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK146788 mRNA. Translation: BAE27432.1. Different initiation.
AK150362 mRNA. Translation: BAE29497.1. Different initiation.
AK151688 mRNA. Translation: BAE30612.1. Different initiation.
AK152171 mRNA. Translation: BAE31003.1. Different initiation.
AK156168 mRNA. Translation: BAE33610.1. Different initiation.
AK165253 mRNA. Translation: BAE38106.1. Different initiation.
BC089000 mRNA. Translation: AAH89000.1.
CCDSiCCDS18137.1.
RefSeqiNP_001009949.3. NM_001009949.3.
XP_006537898.1. XM_006537835.2.
XP_011248301.1. XM_011249999.1.
UniGeneiMm.260210.

3D structure databases

ProteinModelPortaliQ5HZI9.
SMRiQ5HZI9. Positions 29-298.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

IntActiQ5HZI9. 1 interaction.
MINTiMINT-4653162.
STRINGi10090.ENSMUSP00000112044.

PTM databases

iPTMnetiQ5HZI9.
PhosphoSiteiQ5HZI9.

Proteomic databases

EPDiQ5HZI9.
MaxQBiQ5HZI9.
PaxDbiQ5HZI9.
PeptideAtlasiQ5HZI9.
PRIDEiQ5HZI9.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000116341; ENSMUSP00000112044; ENSMUSG00000045973.
ENSMUST00000132815; ENSMUSP00000134132; ENSMUSG00000045973.
GeneIDi230125.
KEGGimmu:230125.
UCSCiuc008ssr.2. mouse.

Organism-specific databases

CTDi92014.
MGIiMGI:2684984. Slc25a51.

Phylogenomic databases

eggNOGiKOG1519. Eukaryota.
ENOG410XNWT. LUCA.
GeneTreeiENSGT00730000110930.
HOGENOMiHOG000233158.
HOVERGENiHBG052423.
InParanoidiQ5HZI9.

Miscellaneous databases

ChiTaRSiSlc25a51. mouse.
PROiQ5HZI9.
SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000045973.
CleanExiMM_MCART1.
ExpressionAtlasiQ5HZI9. baseline and differential.
GenevisibleiQ5HZI9. MM.

Family and domain databases

Gene3Di1.50.40.10. 1 hit.
InterProiIPR018108. Mitochondrial_sb/sol_carrier.
IPR023395. Mt_carrier_dom.
[Graphical view]
PfamiPF00153. Mito_carr. 3 hits.
[Graphical view]
SUPFAMiSSF103506. SSF103506. 1 hit.
PROSITEiPS50920. SOLCAR. 3 hits.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiS2551_MOUSE
AccessioniPrimary (citable) accession number: Q5HZI9
Secondary accession number(s): Q3U190, Q3UCW5
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 10, 2005
Last sequence update: February 15, 2005
Last modified: September 7, 2016
This is version 91 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.