Skip Header

Contribute Send feedback
Read comments (?) or add your own

Q5HZH2 (TSR3_MOUSE) Reviewed, UniProtKB/Swiss-Prot

Last modified December 14, 2011. Version 56. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Probable ribosome biogenesis protein C16orf42 homolog
OrganismMus musculus (Mouse)
Taxonomic identifier10090 [NCBI]
Taxonomic lineageEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Sciurognathi › Muroidea › Muridae › Murinae › Mus › Mus

Protein attributes

Sequence length323 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level

General annotation (Comments)

Function

Probable pre-rRNA processing protein involved in ribosome biogenesis By similarity.

Sequence similarities

Belongs to the TSR3 family.

Ontologies

Keywords
   Biological processRibosome biogenesis
rRNA processing
   PTMPhosphoprotein
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological processrRNA processing

Inferred from electronic annotation. Source: UniProtKB-KW

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 323323Probable ribosome biogenesis protein C16orf42 homolog
PRO_0000278670

Amino acid modifications

Modified residue2661Phosphoserine By similarity

Experimental info

Sequence conflict2451V → E in BAB22003. Ref.1

Sequences

Sequence LengthMass (Da)Tools
Q5HZH2 [UniParc].

Last modified February 15, 2005. Version 1.
Checksum: CCBE907B0F811EBB

FASTA32335,334
        10         20         30         40         50         60 
MGRKKVARGS RKESGRVRRP SGRSLDAFAE EVGAALRASV QPEEAEDQGG PGPAALPCAL 

        70         80         90        100        110        120 
AMWELGHCDP KRCTGRKLAR LGLVRCLRLS QRFGGLVLSP VGTEYVSPAD RQLVAQSGVA 

       130        140        150        160        170        180 
VIDCSWAKLD DTPFQKMRGS HLRLLPYLVA ANPVNYGRPC KLSCVEAFAA AFCIVGFSDL 

       190        200        210        220        230        240 
AVILLRKFKW GKGFLDLNRE LLDKYAACRG PEEVLQAEQG YLASTRDTPE EDIDPFDVDS 

       250        260        270        280        290        300 
GREFVNLNRP VASTRLPEDM DDTDGSEEHS EDSEEDSDEC EEPGPGANGG DSNYSGAEET 

       310        320 
PEQEAQARDS TEIWKGIKKR QRD

« Hide

References

[1]"The transcriptional landscape of the mammalian genome."
Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N., Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K., Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J. expand/collapse author list , Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R., Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T., Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A., Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B., Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M., Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S., Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E., Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D., Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M., Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H., Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V., Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S., Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H., Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N., Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F., Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G., Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z., Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C., Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y., Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S., Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K., Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R., van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H., Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M., Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C., Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S., Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K., Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M., Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C., Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A., Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.
Science 309:1559-1563(2005) [PubMed: 16141072] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Strain: C57BL/6J and NOD.
Tissue: Kidney and Visual cortex.
[2]"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res. 14:2121-2127(2004) [PubMed: 15489334] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Strain: C57BL/6.
Tissue: Eye.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AK002309 mRNA. Translation: BAB22003.1.
AK158743 mRNA. Translation: BAE34637.1.
AK170074 mRNA. Translation: BAE41547.1.
BC089019 mRNA. Translation: AAH89019.1.
IPIIPI00121172.
RefSeqNP_001157190.1. NM_001163718.1.
NP_080952.2. NM_026676.3.
UniGeneMm.180687.

3D structure databases

ProteinModelPortalQ5HZH2.
ModBaseSearch...

Protein-protein interaction databases

STRINGQ5HZH2.

PTM databases

PhosphoSiteQ5HZH2.

Proteomic databases

PRIDEQ5HZH2.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblENSMUST00000063574; ENSMUSP00000068511; ENSMUSG00000015126.
GeneID68327.
KEGGmmu:68327.
NMPDRfig|10090.3.peg.2378.
UCSCuc008baf.2. mouse.

Organism-specific databases

MGIMGI:1915577. 0610007P22Rik.

Phylogenomic databases

HOGENOMHBG527152.
HOVERGENHBG063013.
InParanoidQ5HZH2.
OMATLAMWEL.
OrthoDBEOG4QRH50.
PhylomeDBQ5HZH2.

Gene expression databases

ArrayExpressQ5HZH2.
BgeeQ5HZH2.
CleanExMM_0610007P22RIK.
GenevestigatorQ5HZH2.

Family and domain databases

InterProIPR007177. DUF367.
IPR022968. Rbsm_biogenesis.
IPR007209. RNaseL-inhib_metal-bd_dom.
[Graphical view]
KOK09140.
PANTHERPTHR20426. PTHR20426. 1 hit.
PfamPF04034. DUF367. 1 hit.
PF04068. RLI. 1 hit.
[Graphical view]
ProDomPD016638. DUF367. 1 hit.
[Graphical view] [Entries sharing at least one domain]
ProtoNetSearch...

Other

NextBio327001.

Entry information

Entry nameTSR3_MOUSE
AccessionPrimary (citable) accession number: Q5HZH2
Secondary accession number(s): Q9DD00
Entry history
Integrated into UniProtKB/Swiss-Prot: February 20, 2007
Last sequence update: February 15, 2005
Last modified: December 14, 2011
This is version 56 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Relevant documents

MGD cross-references

Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot

SIMILARITY comments

Index of protein domains and families

to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·Documents