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Protein

Cancer/testis antigen family 45 member A1

Gene

CT45A1

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Names & Taxonomyi

Protein namesi
Recommended name:
Cancer/testis antigen family 45 member A1
Alternative name(s):
Cancer/testis antigen 45-1
Cancer/testis antigen 45A1
Gene namesi
Name:CT45A1
Synonyms:CT45-1
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
ProteomesiUP000005640: Chromosome X

Organism-specific databases

HGNCiHGNC:33267. CT45A1.

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA164718185.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 189189Cancer/testis antigen family 45 member A1PRO_0000308946Add
BLAST

Proteomic databases

PaxDbiQ5HYN5.
PRIDEiQ5HYN5.

PTM databases

PhosphoSiteiQ5HYN5.

Expressioni

Tissue specificityi

Testis specific. Expressed in cancer cell lines.1 Publication

Gene expression databases

BgeeiQ5HYN5.
GenevestigatoriQ5HYN5.

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000359777.

Structurei

3D structure databases

ProteinModelPortaliQ5HYN5.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

eggNOGiNOG125008.
GeneTreeiENSGT00390000016655.
HOGENOMiHOG000082503.
HOVERGENiHBG095520.
InParanoidiQ5HYN5.
OMAiEAIVSTH.
OrthoDBiEOG73V6MH.
PhylomeDBiQ5HYN5.

Family and domain databases

InterProiIPR029307. INT_SG_DDX_CT_C.
[Graphical view]
PfamiPF15300. INT_SG_DDX_CT_C. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q5HYN5-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MTDKTEKVAV DPETVFKRPR ECDSPSYQKR QRMALLARKQ GAGDSLIAGS
60 70 80 90 100
AMSKAKKLMT GHAIPPSQLD SQIDDFTGFS KDRMMQKPGS NAPVGGNVTS
110 120 130 140 150
SFSGDDLECR ETASSPKSQR EINADIKRKL VKELRCVGQK YEKIFEMLEG
160 170 180
VQGPTAVRKR FFESIIKEAA RCMRRDFVKH LKKKLKRMI
Length:189
Mass (Da):21,273
Last modified:February 15, 2005 - v1
Checksum:i3F92AC9CB3C2F396
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY743709 mRNA. Translation: AAW66464.1.
BX537333 Genomic DNA. Translation: CAI43223.1.
BC140913 mRNA. Translation: AAI40914.1.
CCDSiCCDS48174.1.
RefSeqiNP_001017417.1. NM_001017417.2.
XP_005278198.1. XM_005278141.1.
UniGeneiHs.460937.
Hs.535080.

Genome annotation databases

EnsembliENST00000594117; ENSP00000470185; ENSG00000268940.
ENST00000594565; ENSP00000472303; ENSG00000268940.
GeneIDi541466.
KEGGihsa:541466.
UCSCiuc004eyy.3. human.

Polymorphism databases

DMDMi74741538.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY743709 mRNA. Translation: AAW66464.1.
BX537333 Genomic DNA. Translation: CAI43223.1.
BC140913 mRNA. Translation: AAI40914.1.
CCDSiCCDS48174.1.
RefSeqiNP_001017417.1. NM_001017417.2.
XP_005278198.1. XM_005278141.1.
UniGeneiHs.460937.
Hs.535080.

3D structure databases

ProteinModelPortaliQ5HYN5.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000359777.

PTM databases

PhosphoSiteiQ5HYN5.

Polymorphism databases

DMDMi74741538.

Proteomic databases

PaxDbiQ5HYN5.
PRIDEiQ5HYN5.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000594117; ENSP00000470185; ENSG00000268940.
ENST00000594565; ENSP00000472303; ENSG00000268940.
GeneIDi541466.
KEGGihsa:541466.
UCSCiuc004eyy.3. human.

Organism-specific databases

CTDi541466.
GeneCardsiGC0XP134847.
HGNCiHGNC:33267. CT45A1.
MIMi300648. gene.
neXtProtiNX_Q5HYN5.
PharmGKBiPA164718185.
GenAtlasiSearch...

Phylogenomic databases

eggNOGiNOG125008.
GeneTreeiENSGT00390000016655.
HOGENOMiHOG000082503.
HOVERGENiHBG095520.
InParanoidiQ5HYN5.
OMAiEAIVSTH.
OrthoDBiEOG73V6MH.
PhylomeDBiQ5HYN5.

Miscellaneous databases

GenomeRNAii541466.
NextBioi112094.
PROiQ5HYN5.
SOURCEiSearch...

Gene expression databases

BgeeiQ5HYN5.
GenevestigatoriQ5HYN5.

Family and domain databases

InterProiIPR029307. INT_SG_DDX_CT_C.
[Graphical view]
PfamiPF15300. INT_SG_DDX_CT_C. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [MRNA], TISSUE SPECIFICITY, IDENTIFICATION AS A CANCER/TESTIS ANTIGEN.
  2. "The DNA sequence of the human X chromosome."
    Ross M.T., Grafham D.V., Coffey A.J., Scherer S., McLay K., Muzny D., Platzer M., Howell G.R., Burrows C., Bird C.P., Frankish A., Lovell F.L., Howe K.L., Ashurst J.L., Fulton R.S., Sudbrak R., Wen G., Jones M.C.
    , Hurles M.E., Andrews T.D., Scott C.E., Searle S., Ramser J., Whittaker A., Deadman R., Carter N.P., Hunt S.E., Chen R., Cree A., Gunaratne P., Havlak P., Hodgson A., Metzker M.L., Richards S., Scott G., Steffen D., Sodergren E., Wheeler D.A., Worley K.C., Ainscough R., Ambrose K.D., Ansari-Lari M.A., Aradhya S., Ashwell R.I., Babbage A.K., Bagguley C.L., Ballabio A., Banerjee R., Barker G.E., Barlow K.F., Barrett I.P., Bates K.N., Beare D.M., Beasley H., Beasley O., Beck A., Bethel G., Blechschmidt K., Brady N., Bray-Allen S., Bridgeman A.M., Brown A.J., Brown M.J., Bonnin D., Bruford E.A., Buhay C., Burch P., Burford D., Burgess J., Burrill W., Burton J., Bye J.M., Carder C., Carrel L., Chako J., Chapman J.C., Chavez D., Chen E., Chen G., Chen Y., Chen Z., Chinault C., Ciccodicola A., Clark S.Y., Clarke G., Clee C.M., Clegg S., Clerc-Blankenburg K., Clifford K., Cobley V., Cole C.G., Conquer J.S., Corby N., Connor R.E., David R., Davies J., Davis C., Davis J., Delgado O., Deshazo D., Dhami P., Ding Y., Dinh H., Dodsworth S., Draper H., Dugan-Rocha S., Dunham A., Dunn M., Durbin K.J., Dutta I., Eades T., Ellwood M., Emery-Cohen A., Errington H., Evans K.L., Faulkner L., Francis F., Frankland J., Fraser A.E., Galgoczy P., Gilbert J., Gill R., Gloeckner G., Gregory S.G., Gribble S., Griffiths C., Grocock R., Gu Y., Gwilliam R., Hamilton C., Hart E.A., Hawes A., Heath P.D., Heitmann K., Hennig S., Hernandez J., Hinzmann B., Ho S., Hoffs M., Howden P.J., Huckle E.J., Hume J., Hunt P.J., Hunt A.R., Isherwood J., Jacob L., Johnson D., Jones S., de Jong P.J., Joseph S.S., Keenan S., Kelly S., Kershaw J.K., Khan Z., Kioschis P., Klages S., Knights A.J., Kosiura A., Kovar-Smith C., Laird G.K., Langford C., Lawlor S., Leversha M., Lewis L., Liu W., Lloyd C., Lloyd D.M., Loulseged H., Loveland J.E., Lovell J.D., Lozado R., Lu J., Lyne R., Ma J., Maheshwari M., Matthews L.H., McDowall J., McLaren S., McMurray A., Meidl P., Meitinger T., Milne S., Miner G., Mistry S.L., Morgan M., Morris S., Mueller I., Mullikin J.C., Nguyen N., Nordsiek G., Nyakatura G., O'dell C.N., Okwuonu G., Palmer S., Pandian R., Parker D., Parrish J., Pasternak S., Patel D., Pearce A.V., Pearson D.M., Pelan S.E., Perez L., Porter K.M., Ramsey Y., Reichwald K., Rhodes S., Ridler K.A., Schlessinger D., Schueler M.G., Sehra H.K., Shaw-Smith C., Shen H., Sheridan E.M., Shownkeen R., Skuce C.D., Smith M.L., Sotheran E.C., Steingruber H.E., Steward C.A., Storey R., Swann R.M., Swarbreck D., Tabor P.E., Taudien S., Taylor T., Teague B., Thomas K., Thorpe A., Timms K., Tracey A., Trevanion S., Tromans A.C., d'Urso M., Verduzco D., Villasana D., Waldron L., Wall M., Wang Q., Warren J., Warry G.L., Wei X., West A., Whitehead S.L., Whiteley M.N., Wilkinson J.E., Willey D.L., Williams G., Williams L., Williamson A., Williamson H., Wilming L., Woodmansey R.L., Wray P.W., Yen J., Zhang J., Zhou J., Zoghbi H., Zorilla S., Buck D., Reinhardt R., Poustka A., Rosenthal A., Lehrach H., Meindl A., Minx P.J., Hillier L.W., Willard H.F., Wilson R.K., Waterston R.H., Rice C.M., Vaudin M., Coulson A., Nelson D.L., Weinstock G., Sulston J.E., Durbin R.M., Hubbard T., Gibbs R.A., Beck S., Rogers J., Bentley D.R.
    Nature 434:325-337(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  3. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].

Entry informationi

Entry nameiCT451_HUMAN
AccessioniPrimary (citable) accession number: Q5HYN5
Secondary accession number(s): B9EIR8
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 23, 2007
Last sequence update: February 15, 2005
Last modified: January 7, 2015
This is version 63 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome X
    Human chromosome X: entries, gene names and cross-references to MIM
  2. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.