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Q5HYN5

- CT451_HUMAN

UniProt

Q5HYN5 - CT451_HUMAN

Protein

Cancer/testis antigen family 45 member A1

Gene

CT45A1

Organism
Homo sapiens (Human)
Status
Reviewed - Annotation score: 2 out of 5- Experimental evidence at transcript leveli
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    • History
      Entry version 61 (01 Oct 2014)
      Sequence version 1 (15 Feb 2005)
      Previous versions | rss
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    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Cancer/testis antigen family 45 member A1
    Alternative name(s):
    Cancer/testis antigen 45-1
    Cancer/testis antigen 45A1
    Gene namesi
    Name:CT45A1
    Synonyms:CT45-1
    OrganismiHomo sapiens (Human)
    Taxonomic identifieri9606 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
    ProteomesiUP000005640: Chromosome X

    Organism-specific databases

    HGNCiHGNC:33267. CT45A1.

    Pathology & Biotechi

    Organism-specific databases

    PharmGKBiPA164718185.

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 189189Cancer/testis antigen family 45 member A1PRO_0000308946Add
    BLAST

    Proteomic databases

    PaxDbiQ5HYN5.
    PRIDEiQ5HYN5.

    PTM databases

    PhosphoSiteiQ5HYN5.

    Expressioni

    Tissue specificityi

    Testis specific. Expressed in cancer cell lines.1 Publication

    Gene expression databases

    BgeeiQ5HYN5.
    GenevestigatoriQ5HYN5.

    Interactioni

    Protein-protein interaction databases

    STRINGi9606.ENSP00000359777.

    Structurei

    3D structure databases

    ProteinModelPortaliQ5HYN5.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Phylogenomic databases

    eggNOGiNOG125008.
    HOGENOMiHOG000082503.
    HOVERGENiHBG095520.
    InParanoidiQ5HYN5.
    OrthoDBiEOG73V6MH.
    PhylomeDBiQ5HYN5.

    Family and domain databases

    InterProiIPR029307. INT_SG_DDX_CT_C.
    [Graphical view]
    PfamiPF15300. INT_SG_DDX_CT_C. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q5HYN5-1 [UniParc]FASTAAdd to Basket

    « Hide

    MTDKTEKVAV DPETVFKRPR ECDSPSYQKR QRMALLARKQ GAGDSLIAGS    50
    AMSKAKKLMT GHAIPPSQLD SQIDDFTGFS KDRMMQKPGS NAPVGGNVTS 100
    SFSGDDLECR ETASSPKSQR EINADIKRKL VKELRCVGQK YEKIFEMLEG 150
    VQGPTAVRKR FFESIIKEAA RCMRRDFVKH LKKKLKRMI 189
    Length:189
    Mass (Da):21,273
    Last modified:February 15, 2005 - v1
    Checksum:i3F92AC9CB3C2F396
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AY743709 mRNA. Translation: AAW66464.1.
    BX537333 Genomic DNA. Translation: CAI43223.1.
    BC140913 mRNA. Translation: AAI40914.1.
    CCDSiCCDS48174.1.
    RefSeqiNP_001017417.1. NM_001017417.2.
    XP_005278198.1. XM_005278141.1.
    UniGeneiHs.460937.
    Hs.535080.

    Genome annotation databases

    EnsembliENST00000594565; ENSP00000472303; ENSG00000268940.
    GeneIDi541466.
    KEGGihsa:541466.
    UCSCiuc004eyy.3. human.

    Polymorphism databases

    DMDMi74741538.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AY743709 mRNA. Translation: AAW66464.1 .
    BX537333 Genomic DNA. Translation: CAI43223.1 .
    BC140913 mRNA. Translation: AAI40914.1 .
    CCDSi CCDS48174.1.
    RefSeqi NP_001017417.1. NM_001017417.2.
    XP_005278198.1. XM_005278141.1.
    UniGenei Hs.460937.
    Hs.535080.

    3D structure databases

    ProteinModelPortali Q5HYN5.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 9606.ENSP00000359777.

    PTM databases

    PhosphoSitei Q5HYN5.

    Polymorphism databases

    DMDMi 74741538.

    Proteomic databases

    PaxDbi Q5HYN5.
    PRIDEi Q5HYN5.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENST00000594565 ; ENSP00000472303 ; ENSG00000268940 .
    GeneIDi 541466.
    KEGGi hsa:541466.
    UCSCi uc004eyy.3. human.

    Organism-specific databases

    CTDi 541466.
    GeneCardsi GC0XP134847.
    HGNCi HGNC:33267. CT45A1.
    MIMi 300648. gene.
    neXtProti NX_Q5HYN5.
    PharmGKBi PA164718185.
    GenAtlasi Search...

    Phylogenomic databases

    eggNOGi NOG125008.
    HOGENOMi HOG000082503.
    HOVERGENi HBG095520.
    InParanoidi Q5HYN5.
    OrthoDBi EOG73V6MH.
    PhylomeDBi Q5HYN5.

    Miscellaneous databases

    GenomeRNAii 541466.
    NextBioi 112094.
    PROi Q5HYN5.
    SOURCEi Search...

    Gene expression databases

    Bgeei Q5HYN5.
    Genevestigatori Q5HYN5.

    Family and domain databases

    InterProi IPR029307. INT_SG_DDX_CT_C.
    [Graphical view ]
    Pfami PF15300. INT_SG_DDX_CT_C. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [MRNA], TISSUE SPECIFICITY, IDENTIFICATION AS A CANCER/TESTIS ANTIGEN.
    2. "The DNA sequence of the human X chromosome."
      Ross M.T., Grafham D.V., Coffey A.J., Scherer S., McLay K., Muzny D., Platzer M., Howell G.R., Burrows C., Bird C.P., Frankish A., Lovell F.L., Howe K.L., Ashurst J.L., Fulton R.S., Sudbrak R., Wen G., Jones M.C.
      , Hurles M.E., Andrews T.D., Scott C.E., Searle S., Ramser J., Whittaker A., Deadman R., Carter N.P., Hunt S.E., Chen R., Cree A., Gunaratne P., Havlak P., Hodgson A., Metzker M.L., Richards S., Scott G., Steffen D., Sodergren E., Wheeler D.A., Worley K.C., Ainscough R., Ambrose K.D., Ansari-Lari M.A., Aradhya S., Ashwell R.I., Babbage A.K., Bagguley C.L., Ballabio A., Banerjee R., Barker G.E., Barlow K.F., Barrett I.P., Bates K.N., Beare D.M., Beasley H., Beasley O., Beck A., Bethel G., Blechschmidt K., Brady N., Bray-Allen S., Bridgeman A.M., Brown A.J., Brown M.J., Bonnin D., Bruford E.A., Buhay C., Burch P., Burford D., Burgess J., Burrill W., Burton J., Bye J.M., Carder C., Carrel L., Chako J., Chapman J.C., Chavez D., Chen E., Chen G., Chen Y., Chen Z., Chinault C., Ciccodicola A., Clark S.Y., Clarke G., Clee C.M., Clegg S., Clerc-Blankenburg K., Clifford K., Cobley V., Cole C.G., Conquer J.S., Corby N., Connor R.E., David R., Davies J., Davis C., Davis J., Delgado O., Deshazo D., Dhami P., Ding Y., Dinh H., Dodsworth S., Draper H., Dugan-Rocha S., Dunham A., Dunn M., Durbin K.J., Dutta I., Eades T., Ellwood M., Emery-Cohen A., Errington H., Evans K.L., Faulkner L., Francis F., Frankland J., Fraser A.E., Galgoczy P., Gilbert J., Gill R., Gloeckner G., Gregory S.G., Gribble S., Griffiths C., Grocock R., Gu Y., Gwilliam R., Hamilton C., Hart E.A., Hawes A., Heath P.D., Heitmann K., Hennig S., Hernandez J., Hinzmann B., Ho S., Hoffs M., Howden P.J., Huckle E.J., Hume J., Hunt P.J., Hunt A.R., Isherwood J., Jacob L., Johnson D., Jones S., de Jong P.J., Joseph S.S., Keenan S., Kelly S., Kershaw J.K., Khan Z., Kioschis P., Klages S., Knights A.J., Kosiura A., Kovar-Smith C., Laird G.K., Langford C., Lawlor S., Leversha M., Lewis L., Liu W., Lloyd C., Lloyd D.M., Loulseged H., Loveland J.E., Lovell J.D., Lozado R., Lu J., Lyne R., Ma J., Maheshwari M., Matthews L.H., McDowall J., McLaren S., McMurray A., Meidl P., Meitinger T., Milne S., Miner G., Mistry S.L., Morgan M., Morris S., Mueller I., Mullikin J.C., Nguyen N., Nordsiek G., Nyakatura G., O'dell C.N., Okwuonu G., Palmer S., Pandian R., Parker D., Parrish J., Pasternak S., Patel D., Pearce A.V., Pearson D.M., Pelan S.E., Perez L., Porter K.M., Ramsey Y., Reichwald K., Rhodes S., Ridler K.A., Schlessinger D., Schueler M.G., Sehra H.K., Shaw-Smith C., Shen H., Sheridan E.M., Shownkeen R., Skuce C.D., Smith M.L., Sotheran E.C., Steingruber H.E., Steward C.A., Storey R., Swann R.M., Swarbreck D., Tabor P.E., Taudien S., Taylor T., Teague B., Thomas K., Thorpe A., Timms K., Tracey A., Trevanion S., Tromans A.C., d'Urso M., Verduzco D., Villasana D., Waldron L., Wall M., Wang Q., Warren J., Warry G.L., Wei X., West A., Whitehead S.L., Whiteley M.N., Wilkinson J.E., Willey D.L., Williams G., Williams L., Williamson A., Williamson H., Wilming L., Woodmansey R.L., Wray P.W., Yen J., Zhang J., Zhou J., Zoghbi H., Zorilla S., Buck D., Reinhardt R., Poustka A., Rosenthal A., Lehrach H., Meindl A., Minx P.J., Hillier L.W., Willard H.F., Wilson R.K., Waterston R.H., Rice C.M., Vaudin M., Coulson A., Nelson D.L., Weinstock G., Sulston J.E., Durbin R.M., Hubbard T., Gibbs R.A., Beck S., Rogers J., Bentley D.R.
      Nature 434:325-337(2005) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    3. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].

    Entry informationi

    Entry nameiCT451_HUMAN
    AccessioniPrimary (citable) accession number: Q5HYN5
    Secondary accession number(s): B9EIR8
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: October 23, 2007
    Last sequence update: February 15, 2005
    Last modified: October 1, 2014
    This is version 61 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programChordata Protein Annotation Program
    DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Human chromosome X
      Human chromosome X: entries, gene names and cross-references to MIM
    2. MIM cross-references
      Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot

    External Data

    Dasty 3