Q5HYL0 (Q5HYL0_HUMAN) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Putative uncharacterized protein DKFZp686E01144 EMBL CAI46043.1

Gene names

Name:

DKFZp686E01144 EMBL CAI46043.1

Organism

Homo sapiens (Human) EMBL CAI46043.1

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo

Protein attributes

Sequence length	967 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

General annotation (Comments)

Sequence similarities

Contains 1 peptidase M12B domain. RuleBase RU004141 SAAS SAAS002870

Ontologies

Keywords
Cellular component	Secreted SAAS SAAS001590
PTM	Disulfide bond SAAS SAAS002870
Gene Ontology (GO)
Biological process	proteolysis Inferred from electronic annotation. Source: InterPro
Cellular component	proteinaceous extracellular matrix Inferred from electronic annotation. Source: InterPro
Molecular function	metalloendopeptidase activity Inferred from electronic annotation. Source: InterPro zinc ion binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q5HYL0 [UniParc]. Last modified February 15, 2005. Version 1. Checksum: 24685FFB095A9497	FASTA	967	105,354
	10 20 30 40 50 60 MQRAVPEGFG RRKLGSDMGN AERAPGSRSF GPVPTLLLLA AALLAVSDAL GRPSEEDEEL 70 80 90 100 110 120 VVPELERAPG HGTARLRLHA FDQQLDLELR PDSSFLAPGF TLQNVGRKSG SETPLPETDL 130 140 150 160 170 180 AHCFYSGTVN GDPSSAAALS LCEGVRGAFY LLGEAYFIQP LPAASERLAT AAPGEKPPAP 190 200 210 220 230 240 LQFHLLRRNR QGDVGGTCGV VDDEPRPTGK AETEDEDEGT EGEDEGPQWS PQDPALQGVG 250 260 270 280 290 300 QPTGTGSIRK KRFVSSHRYV ETMLVADQSM AEFHGSGLKH YLLTLFSVAA RLYKHPSIRN 310 320 330 340 350 360 SVSLVVVKIL VIHDEQKGPE VTSNAALTLR NFCNWQKQHN PPSDRDAEHY DTAILFTRQD 370 380 390 400 410 420 LCGSQTCDTL GMADVGTVCD PSRSCSVIED DGLQAAFTTA HELGHVFNMP HDDAKQCASL 430 440 450 460 470 480 NGVNQDSHMM ASMLSNLDHS QPWSPCSAYM ITSFLDNGHG ECLMDKPQNP IQLPGDLPGT 490 500 510 520 530 540 SYDANRQCQF TFGEDSKHCP DAASTCSTLW CTGTSGGVLV CQTKHFPWAD GTSCGEGKWC 550 560 570 580 590 600 INGKCVNKTD RKHFDTPFHG SWGMWGPWGD CSRTCGGGVQ YTMRECDNPV PKNGGKYCEG 610 620 630 640 650 660 KRVRYRSCNL EDCPDNNGKT FREEQCEAHN EFSKASFGSG PAVEWIPKYA GVSPKDRCKL 670 680 690 700 710 720 ICQAKGIGYF FVLQPKVVDG TPCSPDSTSV CVQGQCVKAG CDRIIDSKKK FDKCGVCGGN 730 740 750 760 770 780 GSTCKKISGS VTSAKPGYHD IITIPTGATN IEVKQRNQRG SRNNGSFLAI KAADGTYILN 790 800 810 820 830 840 GDYTLSTLEQ DIMYKGVVLR YSGSSAALER IRSFSPLKEP LTIQVLTVGN ALRPKIKYTY 850 860 870 880 890 900 FVKKKKESFN AIPTFSAWVI EEWGECSKSC ELGWQRRLVE CRDINGQPAS ECAKEVKPAS 910 920 930 940 950 960 TRPCADHPCP QWQLGEWSSC SKTCGKGYKK RSLKCLSHDG GVLSHESCDP LKKPKHFIDF CTMAECS

References

[1]	The German cDNA Consortium Wambutt R., Heubner D., Mewes H.W., Weil B., Amid C., Osanger A., Fobo G., Han M., Wiemann S. Submitted (JAN-2005) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Tissue: Colon endothel EMBL CAI46043.1.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	BX647388 mRNA. Translation: CAI46043.1.
IPI	IPI00005908.
UniGene	Hs.643357.
3D structure databases
ProteinModelPortal	Q5HYL0.
SMR	Q5HYL0. Positions 256-548.
ModBase	Search...
Protein-protein interaction databases
STRING	Q5HYL0.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Phylogenomic databases
eggNOG	prNOG18924.
HOVERGEN	HBG004313.
Gene expression databases
ArrayExpress	Q5HYL0.
Family and domain databases
InterPro	IPR006586. ADAM_Cys-rich. IPR010294. ADAM_spacer1. IPR024079. MetalloPept_cat_dom. IPR013274. Pept_M12B_ADAM-TS1. IPR001590. Peptidase_M12B. IPR013273. Peptidase_M12B_ADAM-TS. IPR002870. Peptidase_M12B_N. IPR000884. Thrombospondin_1_rpt. [Graphical view]
Gene3D	G3DSA:3.40.390.10. G3DSA:3.40.390.10. 1 hit.
Pfam	PF05986. ADAM_spacer1. 1 hit. PF01562. Pep_M12B_propep. 1 hit. PF01421. Reprolysin. 1 hit. PF00090. TSP_1. 3 hits. [Graphical view]
PRINTS	PR01858. ADAMTS1. PR01857. ADAMTSFAMILY.
SMART	SM00608. ACR. 1 hit. SM00209. TSP1. 3 hits. [Graphical view]
SUPFAM	SSF82895. TSP1. 3 hits.
PROSITE	PS50215. ADAM_MEPRO. 1 hit. PS50092. TSP1. 3 hits. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Q5HYL0_HUMAN

Accession

Primary (citable) accession number: Q5HYL0

Entry history

Integrated into UniProtKB/TrEMBL:	February 15, 2005
Last sequence update:	February 15, 2005
Last modified:	January 25, 2012
This is version 53 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.