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Protein
Submitted name:

Ankyrin repeat and SOCS box-containing 5

Gene

DKFZp313J0816

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Pathwayi: protein ubiquitination

This protein is involved in the pathway protein ubiquitination, which is part of Protein modification.SAAS annotation
View all proteins of this organism that are known to be involved in the pathway protein ubiquitination and in Protein modification.

GO - Biological processi

Enzyme and pathway databases

UniPathwayiUPA00143

Names & Taxonomyi

Protein namesi
Submitted name:
Ankyrin repeat and SOCS box-containing 5Imported
Submitted name:
cDNA FLJ39122 fis, clone NTONG2006783, weakly similar to ANKYRIN 1Imported
Gene namesi
Name:DKFZp313J0816Imported
Synonyms:ASB5Imported
ORF Names:hCG_40522Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Organism-specific databases

EuPathDBiHostDB:ENSG00000164122.8

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei17 – 43HelicalSequence analysisAdd BLAST27

Keywords - Cellular componenti

Membrane

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA25033

Expressioni

Gene expression databases

BgeeiENSG00000164122
ExpressionAtlasiQ5HYF3 baseline and differential

Structurei

3D structure databases

SMRiQ5HYF3
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini69 – 283ANK_REP_REGIONInterPro annotationAdd BLAST215
Repeati69 – 101ANKPROSITE-ProRule annotationAdd BLAST33
Repeati102 – 134ANKPROSITE-ProRule annotationAdd BLAST33
Repeati135 – 167ANKPROSITE-ProRule annotationAdd BLAST33
Repeati232 – 264ANKPROSITE-ProRule annotationAdd BLAST33
Domaini278 – 329SOCS boxInterPro annotationAdd BLAST52

Keywords - Domaini

ANK repeatPROSITE-ProRule annotationSAAS annotation, Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiKOG0504 Eukaryota
COG0666 LUCA
HOVERGENiHBG001376
KOiK10327
OMAiLEILISW
OrthoDBiEOG091G0DYR

Family and domain databases

CDDicd00204 ANK, 2 hits
cd03724 SOCS_ASB5, 1 hit
Gene3Di1.25.40.20, 1 hit
InterProiView protein in InterPro
IPR002110 Ankyrin_rpt
IPR020683 Ankyrin_rpt-contain_dom
IPR036770 Ankyrin_rpt-contain_sf
IPR037328 ASB5_SOCS
IPR001496 SOCS_box
IPR036036 SOCS_box-like_dom_sf
PfamiView protein in Pfam
PF12796 Ank_2, 2 hits
PF07525 SOCS_box, 1 hit
PRINTSiPR01415 ANKYRIN
SMARTiView protein in SMART
SM00248 ANK, 6 hits
SM00969 SOCS_box, 1 hit
SUPFAMiSSF158235 SSF158235, 1 hit
SSF48403 SSF48403, 1 hit
PROSITEiView protein in PROSITE
PS50297 ANK_REP_REGION, 1 hit
PS50088 ANK_REPEAT, 4 hits
PS50225 SOCS, 1 hit

Sequencei

Sequence statusi: Complete.

Q5HYF3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSVLEENRPF AQQLSNVYFT ILSLFCFKLF VKISLAILSH FYIVKGNRKE
60 70 80 90 100
AARIAAEFYG VTQGQGSWAD RSPLHEAASQ GRLLALRTLL SQGYNVNAVT
110 120 130 140 150
LDHVTPLHEA CLGDHVACAR TLLEAGANVN AITIDGVTPL FNACSQGSPS
160 170 180 190 200
CAELLLEYGA KAQLESCLPS PTHEAASKGH HECLDILISW GIDVDQEIPH
210 220 230 240 250
LGTPLYVACM SQQFHCIWKL LYAGADVQKG KYWDTPLHAA AQQSSTEIVN
260 270 280 290 300
LLLEFGADIN AKNTELLRPI DVATSSSMVE RILLQHEATP SSLYQLCRLC
310 320
IRSYIGKPRL HLIPQLQLPT LLKNFLQYR
Length:329
Mass (Da):36,341
Last modified:May 10, 2005 - v1
Checksum:i966B823CED8A8B71
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK096441 mRNA Translation: BAC04791.1
BX647857 mRNA Translation: CAI46074.1
CH471056 Genomic DNA Translation: EAX04720.1
RefSeqiNP_543150.1, NM_080874.3
XP_005262816.1, XM_005262759.1
UniGeneiHs.591712

Genome annotation databases

GeneIDi140458
KEGGihsa:140458

Similar proteinsi

Entry informationi

Entry nameiQ5HYF3_HUMAN
AccessioniPrimary (citable) accession number: Q5HYF3
Entry historyiIntegrated into UniProtKB/TrEMBL: May 10, 2005
Last sequence update: May 10, 2005
Last modified: May 23, 2018
This is version 134 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

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