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Protein
Submitted name:

Ankyrin repeat and SOCS box-containing 5

Gene

DKFZp313J0816

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

Pathwayi: protein ubiquitination

This protein is involved in the pathway protein ubiquitination, which is part of Protein modification.SAAS annotation
View all proteins of this organism that are known to be involved in the pathway protein ubiquitination and in Protein modification.

GO - Biological processi

Enzyme and pathway databases

UniPathwayiUPA00143.

Names & Taxonomyi

Protein namesi
Submitted name:
Ankyrin repeat and SOCS box-containing 5Imported
Submitted name:
Putative uncharacterized protein DKFZp313J0816Imported
Submitted name:
cDNA FLJ39122 fis, clone NTONG2006783, weakly similar to ANKYRIN 1Imported
Gene namesi
Name:DKFZp313J0816Imported
Synonyms:ASB5Imported
ORF Names:hCG_40522Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei17 – 43HelicalSequence analysisAdd BLAST27

GO - Cellular componenti

Keywords - Cellular componenti

Membrane

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA25033.

Expressioni

Gene expression databases

BgeeiENSG00000164122.
ExpressionAtlasiQ5HYF3. baseline and differential.

Structurei

3D structure databases

SMRiQ5HYF3.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini69 – 283ANK_REP_REGIONInterPro annotationAdd BLAST215
Repeati69 – 101ANKPROSITE-ProRule annotationAdd BLAST33
Repeati102 – 134ANKPROSITE-ProRule annotationAdd BLAST33
Repeati135 – 167ANKPROSITE-ProRule annotationAdd BLAST33
Repeati232 – 264ANKPROSITE-ProRule annotationAdd BLAST33
Domaini278 – 329SOCS boxInterPro annotationAdd BLAST52

Keywords - Domaini

ANK repeatPROSITE-ProRule annotationSAAS annotation, Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiKOG0504. Eukaryota.
COG0666. LUCA.
HOVERGENiHBG001376.
KOiK10327.
OMAiLEILISW.
OrthoDBiEOG091G0DYR.

Family and domain databases

CDDicd00204. ANK. 2 hits.
Gene3Di1.25.40.20. 3 hits.
InterProiView protein in InterPro
IPR002110. Ankyrin_rpt.
IPR020683. Ankyrin_rpt-contain_dom.
IPR001496. SOCS_box.
PfamiView protein in Pfam
PF12796. Ank_2. 2 hits.
PF07525. SOCS_box. 1 hit.
PRINTSiPR01415. ANKYRIN.
SMARTiView protein in SMART
SM00248. ANK. 6 hits.
SM00969. SOCS_box. 1 hit.
SUPFAMiSSF158235. SSF158235. 1 hit.
SSF48403. SSF48403. 1 hit.
PROSITEiView protein in PROSITE
PS50297. ANK_REP_REGION. 1 hit.
PS50088. ANK_REPEAT. 4 hits.
PS50225. SOCS. 1 hit.

Sequencei

Sequence statusi: Complete.

Q5HYF3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSVLEENRPF AQQLSNVYFT ILSLFCFKLF VKISLAILSH FYIVKGNRKE
60 70 80 90 100
AARIAAEFYG VTQGQGSWAD RSPLHEAASQ GRLLALRTLL SQGYNVNAVT
110 120 130 140 150
LDHVTPLHEA CLGDHVACAR TLLEAGANVN AITIDGVTPL FNACSQGSPS
160 170 180 190 200
CAELLLEYGA KAQLESCLPS PTHEAASKGH HECLDILISW GIDVDQEIPH
210 220 230 240 250
LGTPLYVACM SQQFHCIWKL LYAGADVQKG KYWDTPLHAA AQQSSTEIVN
260 270 280 290 300
LLLEFGADIN AKNTELLRPI DVATSSSMVE RILLQHEATP SSLYQLCRLC
310 320
IRSYIGKPRL HLIPQLQLPT LLKNFLQYR
Length:329
Mass (Da):36,341
Last modified:May 10, 2005 - v1
Checksum:i966B823CED8A8B71
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK096441 mRNA. Translation: BAC04791.1.
BX647857 mRNA. Translation: CAI46074.1.
CH471056 Genomic DNA. Translation: EAX04720.1.
RefSeqiNP_543150.1. NM_080874.3.
XP_005262816.1. XM_005262759.1.
UniGeneiHs.591712.

Genome annotation databases

GeneIDi140458.
KEGGihsa:140458.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.

Entry informationi

Entry nameiQ5HYF3_HUMAN
AccessioniPrimary (citable) accession number: Q5HYF3
Entry historyiIntegrated into UniProtKB/TrEMBL: May 10, 2005
Last sequence update: May 10, 2005
Last modified: July 5, 2017
This is version 125 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.