Reviewed,
UniProtKB/Swiss-Prot Q5HXU1 (DNAE2_GLUOX)
Last modified
November 25, 2008.
Version 23.
History...
Clusters with 100%,
90%,
50% identity |
Documents (1) |
Third-party data |
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Names and origin
| Protein names | Recommended name: Error-prone DNA polymerase EC=2.7.7.7 | ||||
| Gene names |
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| Encoded on | Plasmid pGOX1 | ||||
| Organism | Gluconobacter oxydans (Gluconobacter suboxydans) [Complete proteome] [HAMAP] | ||||
| Taxonomic identifier | 442 [NCBI] | ||||
| Taxonomic lineage | Bacteria › Proteobacteria › Alphaproteobacteria › Rhodospirillales › Acetobacteraceae › Gluconobacter |
Protein attributes
| Sequence length | 901 AA. |
| Sequence status | Complete. |
| Sequence processing | The displayed sequence is not processed. |
| Protein existence | Inferred from homology. |
General annotation (Comments)
| Function | DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase By similarity. |
| Catalytic activity | Deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1). |
| Subcellular location | CytoplasmProbable. |
| Sequence similarities | Belongs to the DNA polymerase type-C family. DnaE2 subfamily. |
Ontologies
Keywords | |
|---|---|
| Biological process | DNA damage DNA repair DNA replication |
| Cellular component | Cytoplasm |
| Molecular function | DNA-directed DNA polymerase Nucleotidyltransferase Transferase |
| Technical term | Complete proteome Plasmid |
Gene Ontology (GO) | |
| Biological process | DNA replication Inferred from electronic annotation. Source: InterPro error-prone DNA repairInferred from electronic annotation. Source: HAMAP |
| Cellular component | cytoplasm Inferred from electronic annotation. Source: HAMAP |
| Molecular function | 3'-5' exonuclease activity Inferred from electronic annotation. Source: InterPro DNA-directed DNA polymerase activityInferred from electronic annotation. Source: HAMAP nucleic acid bindingInferred from electronic annotation. Source: InterPro |
| Complete GO annotation... | |
Sequence annotation (Features)
| Feature key | Position(s) | Length | Description | Graphical view | Feature identifier | ||
Molecule processing | |||||||
|---|---|---|---|---|---|---|---|
| Chain | 1 – 901 | 901 | Error-prone DNA polymerase | PRO_0000103380 | |||
Sequences
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References
| [1] | "Complete genome sequence of the acetic acid bacterium Gluconobacter oxydans." Prust C., Hoffmeister M., Liesegang H., Wiezer A., Fricke W.F., Ehrenreich A., Gottschalk G., Deppenmeier U. Nat. Biotechnol. 23:195-200(2005) [PubMed: 15665824] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: 621H. |
Cross-references
Sequence databases | |
|---|---|
| CP000004 Genomic DNA. Translation: AAW59662.1. | |
| RefSeq | YP_190318.1. |
3D structure databases | |
| ModBase | Search... |
Genome annotation databases | |
| GeneID | 3248493. |
| GenomeReviews | Gene locus GOX2598 in contig CP000004_GR. |
| KEGG | gox:GOX2598. |
| NMPDR | fig|290633.1.peg.2527. |
Organism-specific databases | |
| CMR | Search... |
Phylogenomic databases | |
| HOGENOM | Q5HXU1. |
Enzyme and pathway databases | |
| BioCyc | GOXY290633:GOX2598-MON. |
Family and domain databases | |
| HAMAP | MF_01902. Divergent sequence. [Tree] |
| InterPro | IPR011708. DNA_pol3_alpha. IPR004365. NA_bd_OB_tRNA-helicase. IPR004805. PolC_alpha. [Graphical view] |
| Pfam | PF07733. DNA_pol3_alpha. 1 hit. PF01336. tRNA_anti. 1 hit. [Graphical view] |
| TIGRFAMs | TIGR00594. polc. 1 hit. |
| ProtoNet | Search... |
Entry information
| Entry name | DNAE2_GLUOX | ||||||||
| Accession | Primary (citable) accession number: Q5HXU1 | ||||||||
| Entry history |
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| Entry status | Reviewed (UniProtKB/Swiss-Prot) | ||||||||
| Annotation project | HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes) | ||||||||

Clusters with


