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Q5HWW2 (IF3_CAMJR) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 61. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Translation initiation factor IF-3
Gene names
Name:infC
Ordered Locus Names:CJE0200
OrganismCampylobacter jejuni (strain RM1221) [Complete proteome] [HAMAP]
Taxonomic identifier195099 [NCBI]
Taxonomic lineageBacteriaProteobacteriaEpsilonproteobacteriaCampylobacteralesCampylobacteraceaeCampylobacter

Protein attributes

Sequence length172 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Function

IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins By similarity. HAMAP-Rule MF_00080

Subunit structure

Monomer By similarity. HAMAP-Rule MF_00080

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00080.

Sequence similarities

Belongs to the IF-3 family.

Ontologies

Keywords
   Biological processProtein biosynthesis
   Cellular componentCytoplasm
   Molecular functionInitiation factor
   Technical term3D-structure
Complete proteome
Gene Ontology (GO)
   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functiontranslation initiation factor activity

Inferred from electronic annotation. Source: UniProtKB-KW

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 172172Translation initiation factor IF-3 HAMAP-Rule MF_00080
PRO_0000177499

Secondary structure

............... 172
Helix Strand Turn

Details...

Sequences

Sequence LengthMass (Da)Tools
Q5HWW2 [UniParc].

Last modified February 15, 2005. Version 1.
Checksum: E336083CDC1B87C7

FASTA17219,781
        10         20         30         40         50         60 
MSKEKEVLLN EEIRADEIRC VGDDGKVYGI ISSDEALEIA NRLGLDLVMI AADAKPPVCK 

        70         80         90        100        110        120 
IMDYGKFRYQ QEKKQKEAKK KQKVIDIKEI KLSVKIAQND INYKVKHALE FLEQGKHVRF 

       130        140        150        160        170 
RVFLKGREMA TPEAGVALLE KIWTMIENEA NRDKEPNFEG RYVNMLVTPK KA 

« Hide

References

[1]"Major structural differences and novel potential virulence mechanisms from the genomes of multiple Campylobacter species."
Fouts D.E., Mongodin E.F., Mandrell R.E., Miller W.G., Rasko D.A., Ravel J., Brinkac L.M., DeBoy R.T., Parker C.T., Daugherty S.C., Dodson R.J., Durkin A.S., Madupu R., Sullivan S.A., Shetty J.U., Ayodeji M.A., Shvartsbeyn A., Schatz M.C. expand/collapse author list , Badger J.H., Fraser C.M., Nelson K.E.
PLoS Biol. 3:72-85(2005) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: RM1221.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000025 Genomic DNA. Translation: AAW34794.1.
RefSeqYP_178223.1. NC_003912.7.

3D structure databases

PDBe
RCSB-PDB
PDBj
EntryMethodResolution (Å)ChainPositionsPDBsum
2M71NMR-A83-172[»]
ProteinModelPortalQ5HWW2.
SMRQ5HWW2. Positions 5-80.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING195099.CJE0200.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAW34794; AAW34794; CJE0200.
GeneID3230963.
KEGGcjr:CJE0200.
PATRIC20042112. VBICamJej134361_0205.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0290.
HOGENOMHOG000035157.
KOK02520.
OMAPRYNEFI.
OrthoDBEOG63JRGJ.

Enzyme and pathway databases

BioCycCJEJ195099:GJC0-205-MONOMER.

Family and domain databases

Gene3D3.10.20.80. 1 hit.
3.30.110.10. 1 hit.
HAMAPMF_00080. IF_3.
InterProIPR019813. Translation_initiation_fac3_CS.
IPR001288. Translation_initiation_fac_3.
IPR019815. Translation_initiation_fac_3_C.
IPR019814. Translation_initiation_fac_3_N.
[Graphical view]
PANTHERPTHR10938. PTHR10938. 1 hit.
PfamPF00707. IF3_C. 1 hit.
PF05198. IF3_N. 1 hit.
[Graphical view]
SUPFAMSSF54364. SSF54364. 1 hit.
SSF55200. SSF55200. 1 hit.
TIGRFAMsTIGR00168. infC. 1 hit.
PROSITEPS00938. IF3. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameIF3_CAMJR
AccessionPrimary (citable) accession number: Q5HWW2
Entry history
Integrated into UniProtKB/Swiss-Prot: August 16, 2005
Last sequence update: February 15, 2005
Last modified: May 14, 2014
This is version 61 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PDB cross-references

Index of Protein Data Bank (PDB) cross-references

Translation initiation factors

List of translation initiation factor entries