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Protein

tRNA pseudouridine synthase B

Gene

truB

Organism
Campylobacter jejuni (strain RM1221)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.UniRule annotation

Catalytic activityi

tRNA uridine(55) = tRNA pseudouridine(55).UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei38NucleophileUniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionIsomerase
Biological processtRNA processing

Names & Taxonomyi

Protein namesi
Recommended name:
tRNA pseudouridine synthase BUniRule annotation (EC:5.4.99.25UniRule annotation)
Alternative name(s):
tRNA pseudouridine(55) synthaseUniRule annotation
Short name:
Psi55 synthaseUniRule annotation
tRNA pseudouridylate synthaseUniRule annotation
tRNA-uridine isomeraseUniRule annotation
Gene namesi
Name:truBUniRule annotation
Ordered Locus Names:CJE1245
OrganismiCampylobacter jejuni (strain RM1221)
Taxonomic identifieri195099 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaEpsilonproteobacteriaCampylobacteralesCampylobacteraceaeCampylobacter

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001218121 – 272tRNA pseudouridine synthase BAdd BLAST272

Structurei

3D structure databases

ProteinModelPortaliQ5HU02
SMRiQ5HU02
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000231225
KOiK03177
OMAiVDCSKGT

Family and domain databases

HAMAPiMF_01080 TruB_bact, 1 hit
InterProiView protein in InterPro
IPR020103 PsdUridine_synth_cat_dom_sf
IPR002501 PsdUridine_synth_N
IPR014780 tRNA_psdUridine_synth_TruB
PANTHERiPTHR13767 PTHR13767, 1 hit
PfamiView protein in Pfam
PF01509 TruB_N, 1 hit
SUPFAMiSSF55120 SSF55120, 1 hit
TIGRFAMsiTIGR00431 TruB, 1 hit

Sequencei

Sequence statusi: Complete.

Q5HU02-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNKIFAAFKP KGLSSNAFLS TLKKKYKNKK AGYSGTLDPF AKGVLIVAFG
60 70 80 90 100
QYTKLFRFLK KTPKTYKATL WLGVYSLSLD DQNIKEIQNI KEFDLANLKQ
110 120 130 140 150
IIDQMQGIIS YTPPQFSAKR INGTRAYELA KKGIEANLKP CQMEVFDCKI
160 170 180 190 200
LSYNHPFLNI EITVSEGAYI RSYCELFARK LGINATLSSL ERIKEGKFVY
210 220 230 240 250
NNEKSLNVLK YINLKPNFIK DLNKLENGAK IFVEELEFHD EGDYYIETEK
260 270
YFSIINIKEN TVKYLLNKVE KC
Length:272
Mass (Da):31,337
Last modified:February 15, 2005 - v1
Checksum:i7BEE86D4FBD1E815
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000025 Genomic DNA Translation: AAW35567.1
RefSeqiWP_002852653.1, NC_003912.7

Genome annotation databases

EnsemblBacteriaiAAW35567; AAW35567; CJE1245
KEGGicjr:CJE1245

Similar proteinsi

Entry informationi

Entry nameiTRUB_CAMJR
AccessioniPrimary (citable) accession number: Q5HU02
Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 26, 2005
Last sequence update: February 15, 2005
Last modified: March 28, 2018
This is version 72 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health