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Protein

tRNA pseudouridine synthase B

Gene

truB

Organism
Campylobacter jejuni (strain RM1221)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.UniRule annotation

Catalytic activityi

tRNA uridine(55) = tRNA pseudouridine(55).UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei38 – 381NucleophileUniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Isomerase

Keywords - Biological processi

tRNA processing

Enzyme and pathway databases

BioCyciCJEJ195099:GJC0-1271-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
tRNA pseudouridine synthase BUniRule annotation (EC:5.4.99.25UniRule annotation)
Alternative name(s):
tRNA pseudouridine(55) synthaseUniRule annotation
Short name:
Psi55 synthaseUniRule annotation
tRNA pseudouridylate synthaseUniRule annotation
tRNA-uridine isomeraseUniRule annotation
Gene namesi
Name:truBUniRule annotation
Ordered Locus Names:CJE1245
OrganismiCampylobacter jejuni (strain RM1221)
Taxonomic identifieri195099 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaEpsilonproteobacteriaCampylobacteralesCampylobacteraceaeCampylobacter

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 272272tRNA pseudouridine synthase BPRO_0000121812Add
BLAST

Structurei

3D structure databases

ProteinModelPortaliQ5HU02.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000231225.
KOiK03177.
OMAiDYSFLIP.

Family and domain databases

HAMAPiMF_01080. TruB_bact. 1 hit.
InterProiIPR020103. PsdUridine_synth_cat_dom.
IPR002501. PsdUridine_synth_N.
IPR014780. tRNA_psdUridine_synth_TruB.
[Graphical view]
PANTHERiPTHR13767. PTHR13767. 1 hit.
PfamiPF01509. TruB_N. 1 hit.
[Graphical view]
SUPFAMiSSF55120. SSF55120. 1 hit.
TIGRFAMsiTIGR00431. TruB. 1 hit.

Sequencei

Sequence statusi: Complete.

Q5HU02-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNKIFAAFKP KGLSSNAFLS TLKKKYKNKK AGYSGTLDPF AKGVLIVAFG
60 70 80 90 100
QYTKLFRFLK KTPKTYKATL WLGVYSLSLD DQNIKEIQNI KEFDLANLKQ
110 120 130 140 150
IIDQMQGIIS YTPPQFSAKR INGTRAYELA KKGIEANLKP CQMEVFDCKI
160 170 180 190 200
LSYNHPFLNI EITVSEGAYI RSYCELFARK LGINATLSSL ERIKEGKFVY
210 220 230 240 250
NNEKSLNVLK YINLKPNFIK DLNKLENGAK IFVEELEFHD EGDYYIETEK
260 270
YFSIINIKEN TVKYLLNKVE KC
Length:272
Mass (Da):31,337
Last modified:February 15, 2005 - v1
Checksum:i7BEE86D4FBD1E815
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000025 Genomic DNA. Translation: AAW35567.1.
RefSeqiWP_002852653.1. NC_003912.7.

Genome annotation databases

EnsemblBacteriaiAAW35567; AAW35567; CJE1245.
KEGGicjr:CJE1245.
PATRICi20044286. VBICamJej134361_1261.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000025 Genomic DNA. Translation: AAW35567.1.
RefSeqiWP_002852653.1. NC_003912.7.

3D structure databases

ProteinModelPortaliQ5HU02.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAW35567; AAW35567; CJE1245.
KEGGicjr:CJE1245.
PATRICi20044286. VBICamJej134361_1261.

Phylogenomic databases

HOGENOMiHOG000231225.
KOiK03177.
OMAiDYSFLIP.

Enzyme and pathway databases

BioCyciCJEJ195099:GJC0-1271-MONOMER.

Family and domain databases

HAMAPiMF_01080. TruB_bact. 1 hit.
InterProiIPR020103. PsdUridine_synth_cat_dom.
IPR002501. PsdUridine_synth_N.
IPR014780. tRNA_psdUridine_synth_TruB.
[Graphical view]
PANTHERiPTHR13767. PTHR13767. 1 hit.
PfamiPF01509. TruB_N. 1 hit.
[Graphical view]
SUPFAMiSSF55120. SSF55120. 1 hit.
TIGRFAMsiTIGR00431. TruB. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiTRUB_CAMJR
AccessioniPrimary (citable) accession number: Q5HU02
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 26, 2005
Last sequence update: February 15, 2005
Last modified: September 7, 2016
This is version 67 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.