Reviewed, UniProtKB/Swiss-Prot Q5HSS7 (SELD_CAMJR)

Names and origin

Protein names

Recommended name:
    Selenide, water dikinase
    EC=2.7.9.3
Alternative name(s):
    Selenophosphate synthetase
    Selenium donor protein

Gene names

Name:	selD
Ordered Locus Names:	CJE1677

Organism

Campylobacter jejuni (strain RM1221) [Complete proteome] [HAMAP]

Taxonomic identifier

195099 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Epsilonproteobacteria › Campylobacterales › Campylobacteraceae › Campylobacter

Protein attributes

Sequence length	340 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	Synthesizes selenophosphate from selenide and ATP By similarity.
Catalytic activity	ATP + selenide + H2O = AMP + selenophosphate + phosphate. HAMAP MF_00625
Cofactor	Magnesium By similarity.
Sequence similarities	Belongs to the selenophosphate synthetase 1 family. Class I subfamily.

Ontologies

Keywords
Coding sequence diversity	Selenocysteine
Ligand	ATP-binding Magnesium Nucleotide-binding Selenium
Molecular function	Kinase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Molecular function	ATP binding Inferred from electronic annotation. Source: HAMAP magnesium ion binding Inferred from electronic annotation. Source: HAMAP selenide, water dikinase activity Inferred from electronic annotation. Source: HAMAP selenium binding Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 340	340	Selenide, water dikinase HAMAP MF_00625		PRO_1000051595
Regions
	Nucleotide binding	227 – 233	7	ATP Potential
Sites
	Active site	17	1	Potential
	Site	20	1	Important for catalytic activity By similarity
Amino acid modifications
	Non-standard residue	17	1	Selenocysteine Potential

Sequences

	Sequence		Length	Mass (Da)
	Q5HSS7-1 [UniParc]. Last modified February 26, 2008. Version 2. Checksum: 12259CB8C6B2D622	FASTA	340	37,194
	10 20 30 40 50 60 MQYKNQNLTH FVKAAGUAAK LSPGGLKTIL NFMQKTPALL SDIGNNEDAS VYQISRDLAL 70 80 90 100 110 120 VQTLDFITPI VDSAYHFGAI AAANALSDVF AMGAEVINAL NIVGFDTCNH DVNILKELLE 130 140 150 160 170 180 GANDKVQECN ALVVGGHTIE STELFFGLSV TGKVHPSKFI ANNTSKIGDC IILTKPLGTG 190 200 210 220 230 240 ILSTALKAQM LNQKHLDIML KNMMELNYKA SQIALKFHPS AMSDVTGFGL LGHLKEMLNK 250 260 270 280 290 300 NISFEIFQNE ILFLEGAKEY FNMGLIPAGA YKNLEFIKEL IPDLNEEKLL LCDPQTSGGL 310 320 330 340 LISISEKESL ECLKKLEDEN IQAKIIAKVV NKQENDIIIS

References

[1]

"Major structural differences and novel potential virulence mechanisms from the genomes of multiple Campylobacter species." Fouts D.E., Mongodin E.F., Mandrell R.E., Miller W.G., Rasko D.A., Ravel J., Brinkac L.M., DeBoy R.T., Parker C.T., Daugherty S.C., Dodson R.J., Durkin A.S., Madupu R., Sullivan S.A., Shetty J.U., Ayodeji M.A., Shvartsbeyn A., Schatz M.C. , Badger J.H., Fraser C.M., Nelson K.E. PLoS Biol. 3:72-85(2005) [PubMed: 15660156] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	CP000025 Genomic DNA. Translation: AAW36110.1.
RefSeq	YP_179658.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	Q5HSS7.
Genome annotation databases
GeneID	3232305.
GenomeReviews	Gene locus CJE1677 in contig CP000025_GR.
KEGG	cjr:CJE1677.
TIGR	CJE1677.
Phylogenomic databases
HOGENOM	Q5HSS7.
OMA	GGHTVED.
Enzyme and pathway databases
BioCyc	CJEJ195099:CJE_1677-MON.
Family and domain databases
HAMAP	MF_00625. [Tree]
InterPro	IPR000728. AIR_synth. IPR010918. AIR_synth_C. IPR004536. SelD. [Graphical view]
Pfam	PF00586. AIRS. 1 hit. PF02769. AIRS_C. 1 hit. [Graphical view]
PIRSF	PIRSF036407. Selenphspht_syn. 1 hit.
TIGRFAMs	TIGR00476. selD. 1 hit.
ProtoNet	Search...

Entry information

Entry name

SELD_CAMJR

Accession

Primary (citable) accession number: Q5HSS7

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 15, 2008
Last sequence update:	February 26, 2008
Last modified:	November 3, 2009
This is version 25 of the entry and version 2 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)