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Protein

DNA-directed RNA polymerase subunit omega

Gene

rpoZ

Organism
Staphylococcus epidermidis (strain ATCC 35984 / RP62A)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.UniRule annotation

Catalytic activityi

Nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1).UniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Nucleotidyltransferase, Transferase

Keywords - Biological processi

Transcription

Names & Taxonomyi

Protein namesi
Recommended name:
DNA-directed RNA polymerase subunit omegaUniRule annotation (EC:2.7.7.6UniRule annotation)
Short name:
RNAP omega subunitUniRule annotation
Alternative name(s):
RNA polymerase omega subunitUniRule annotation
Transcriptase subunit omegaUniRule annotation
Gene namesi
Name:rpoZUniRule annotation
Ordered Locus Names:SERP0777
OrganismiStaphylococcus epidermidis (strain ATCC 35984 / RP62A)
Taxonomic identifieri176279 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesStaphylococcaceaeStaphylococcus
Proteomesi
  • UP000000531 Componenti: Chromosome

Subcellular locationi

Keywords - Cellular componenti

DNA-directed RNA polymerase

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001289841 – 70DNA-directed RNA polymerase subunit omegaAdd BLAST70

Interactioni

Subunit structurei

The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.UniRule annotation

Protein-protein interaction databases

STRINGi176279.SERP0777.

Structurei

3D structure databases

ProteinModelPortaliQ5HPY0.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the RNA polymerase subunit omega family.UniRule annotation

Phylogenomic databases

eggNOGiENOG41067UH. Bacteria.
COG1758. LUCA.
HOGENOMiHOG000245722.
KOiK03060.
OMAiYHSAKPV.

Family and domain databases

Gene3Di3.90.940.10. 1 hit.
HAMAPiMF_00366. RNApol_bact_RpoZ. 1 hit.
InterProiIPR003716. DNA-dir_RNA_pol_omega.
IPR006110. Pol_omega/K/RPB6.
IPR012293. RNAP_RPB6_omega.
[Graphical view]
PfamiPF01192. RNA_pol_Rpb6. 1 hit.
[Graphical view]
SMARTiSM01409. RNA_pol_Rpb6. 1 hit.
[Graphical view]
SUPFAMiSSF63562. SSF63562. 1 hit.
TIGRFAMsiTIGR00690. rpoZ. 1 hit.

Sequencei

Sequence statusi: Complete.

Q5HPY0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLNPPLNQLT AKVNSKYLIA TTAAKRAREL DERRETALLD QYQSAKPVGK
60 70
ALEEIADGKI EPVVPKEYLG
Length:70
Mass (Da):7,766
Last modified:February 15, 2005 - v1
Checksum:i1056616A8D797B57
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000029 Genomic DNA. Translation: AAW54188.1.
RefSeqiWP_002446252.1. NC_002976.3.

Genome annotation databases

EnsemblBacteriaiAAW54188; AAW54188; SERP0777.
KEGGiser:SERP0777.
PATRICi19612425. VBIStaEpi130894_0755.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000029 Genomic DNA. Translation: AAW54188.1.
RefSeqiWP_002446252.1. NC_002976.3.

3D structure databases

ProteinModelPortaliQ5HPY0.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi176279.SERP0777.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAW54188; AAW54188; SERP0777.
KEGGiser:SERP0777.
PATRICi19612425. VBIStaEpi130894_0755.

Phylogenomic databases

eggNOGiENOG41067UH. Bacteria.
COG1758. LUCA.
HOGENOMiHOG000245722.
KOiK03060.
OMAiYHSAKPV.

Family and domain databases

Gene3Di3.90.940.10. 1 hit.
HAMAPiMF_00366. RNApol_bact_RpoZ. 1 hit.
InterProiIPR003716. DNA-dir_RNA_pol_omega.
IPR006110. Pol_omega/K/RPB6.
IPR012293. RNAP_RPB6_omega.
[Graphical view]
PfamiPF01192. RNA_pol_Rpb6. 1 hit.
[Graphical view]
SMARTiSM01409. RNA_pol_Rpb6. 1 hit.
[Graphical view]
SUPFAMiSSF63562. SSF63562. 1 hit.
TIGRFAMsiTIGR00690. rpoZ. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiRPOZ_STAEQ
AccessioniPrimary (citable) accession number: Q5HPY0
Entry historyi
Integrated into UniProtKB/Swiss-Prot: August 30, 2005
Last sequence update: February 15, 2005
Last modified: November 2, 2016
This is version 74 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.