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Reviewed, UniProtKB/Swiss-Prot Q5HPW0 (FABG_STAEQ)

Last modified November 3, 2009. Version 33. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data | Customize display text xml rdf/xml gff fasta
Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents

Names and origin

Protein namesRecommended name:
    3-oxoacyl-[acyl-carrier-protein] reductase
    EC=1.1.1.100
Alternative name(s):
    3-ketoacyl-acyl carrier protein reductase
Gene names
Name: fabG
Ordered Locus Names: SERP0797
OrganismStaphylococcus epidermidis (strain ATCC 35984 / RP62A) [Complete proteome] [HAMAP]
Taxonomic identifier176279 [NCBI]
Taxonomic lineageBacteriaFirmicutesBacillalesStaphylococcus

Protein attributes

Sequence length244 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is not processed.
Protein existenceInferred from homology.

General annotation (Comments)

Catalytic activity

(3R)-3-hydroxyacyl-[acyl-carrier-protein] + NADP+ = 3-oxoacyl-[acyl-carrier-protein] + NADPH.

Pathway

Lipid metabolism; fatty acid biosynthesis.

Sequence similarities

Belongs to the short-chain dehydrogenases/reductases (SDR) family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 2442443-oxoacyl-[acyl-carrier-protein] reductase
PRO_0000054690

Regions

Nucleotide binding7 – 3226NADP By similarity

Sites

Active site1521Proton acceptor By similarity
Binding site1391Substrate By similarity

Sequences

Sequence LengthMass (Da)Tools
Q5HPW0-1 [UniParc].

Last modified February 15, 2005. Version 1.
Checksum: 8F4CEC8E13E5BA09

FASTA24426,074
        10         20         30         40         50         60 
MNKSALVTGA SRGIGRSIAL QLAEEGYNVA VNYAGSKDKA EAVVEEIKAK GVESFAIQAN 

        70         80         90        100        110        120 
VAKGDEVKEM IKEVVSQFGS VDVLVNNAGI TKDNLLMRMK EQEWDDVIDT NLKGVFNCIQ 

       130        140        150        160        170        180 
KVTPQMLRQR SGAIINLTSI VGAMGNPGQA NYVATKAGVI GLTKTAAREL ASRGITVNAV 

       190        200        210        220        230        240 
APGFIVSDMT NALSDDLKDQ MLEQIPLKRF GEDTDIANTV AFLASDKAKY ITGQTIHVNG 


GMYM 

« Hide

References

[1]"Insights on evolution of virulence and resistance from the complete genome analysis of an early methicillin-resistant Staphylococcus aureus strain and a biofilm-producing methicillin-resistant Staphylococcus epidermidis strain."
Gill S.R., Fouts D.E., Archer G.L., Mongodin E.F., DeBoy R.T., Ravel J., Paulsen I.T., Kolonay J.F., Brinkac L.M., Beanan M.J., Dodson R.J., Daugherty S.C., Madupu R., Angiuoli S.V., Durkin A.S., Haft D.H., Vamathevan J.J., Khouri H. expand/collapse author list , Utterback T.R., Lee C., Dimitrov G., Jiang L., Qin H., Weidman J., Tran K., Kang K.H., Hance I.R., Nelson K.E., Fraser C.M.
J. Bacteriol. 187:2426-2438(2005) [PubMed: 15774886] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases

CP000029 Genomic DNA. Translation: AAW54128.1.
RefSeqYP_188380.1.

3D structure databases

ModBaseSearch...

Protein-protein interaction databases

STRINGQ5HPW0.

Genome annotation databases

GeneID3241396.
GenomeReviewsGene locus SERP0797 in contig CP000029_GR.
KEGGser:SERP0797.
TIGRSERP0797.

Phylogenomic databases

HOGENOMQ5HPW0.
OMAITGTELH.

Enzyme and pathway databases

BioCycSEPI176279:SERP0797-MON.

Family and domain databases

InterProIPR011284. 3oxo_ACP_reduc.
IPR002198. DH_sc/Rdtase_SDR.
IPR002347. Glc/ribitol_DH.
IPR016040. NAD(P)-bd_dom.
[Graphical view]
Gene3DG3DSA:3.40.50.720. NAD(P)-bd. 1 hit.
PANTHERPTHR19410. ADH_short_C2. 1 hit.
PfamPF00106. adh_short. 1 hit.
[Graphical view]
PRINTSPR00081. GDHRDH.
PR00080. SDRFAMILY.
TIGRFAMsTIGR01830. 3oxo_ACP_reduc. 1 hit.
PROSITEPS00061. ADH_SHORT. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameFABG_STAEQ
AccessionPrimary (citable) accession number: Q5HPW0
Entry history
Integrated into UniProtKB/Swiss-Prot: December 20, 2005
Last sequence update: February 15, 2005
Last modified: November 3, 2009
This is version 33 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation projectHAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents