Skip Header

Contribute Send feedback
Read comments (?) or add your own

Q5HMA0 (ALD1_STAEQ) Reviewed, UniProtKB/Swiss-Prot

Last modified May 1, 2013. Version 57. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Putative aldehyde dehydrogenase SERP1729
EC=1.2.1.3
Gene names
Ordered Locus Names:SERP1729
OrganismStaphylococcus epidermidis (strain ATCC 35984 / RP62A) [Complete proteome] [HAMAP]
Taxonomic identifier176279 [NCBI]
Taxonomic lineageBacteria › Firmicutes › Bacilli › Bacillales › Staphylococcus ›

Protein attributes

Sequence length475 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

An aldehyde + NAD+ + H2O = a carboxylate + NADH.

Sequence similarities

Belongs to the aldehyde dehydrogenase family.

Ontologies

Keywords
   LigandNAD
   Molecular functionOxidoreductase
   Technical termComplete proteome
Gene Ontology (GO)
   Molecular_functionaldehyde dehydrogenase (NAD) activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 475475Putative aldehyde dehydrogenase SERP1729
PRO_0000293562

Regions

Nucleotide binding201 – 2077NAD By similarity

Sites

Active site2451 By similarity
Active site2791 By similarity

Sequences

Sequence LengthMass (Da)Tools
Q5HMA0 [UniParc].

Last modified February 15, 2005. Version 1.
Checksum: 905E024191EE75D1

FASTA47551,890
        10         20         30         40         50         60 
MRNFTKQYIN GEWVDSASGE TIDVINPATE EVMGKIAKGN EEDVNKAVDA ADKVYLEFRH 

        70         80         90        100        110        120 
SSVEERRELL DKIVKEYQNR KNDLIEAITD ELGAPLSVSE NVHYQMGLNH FTAARDALDS 

       130        140        150        160        170        180 
FQFEEQRGDD LVVKEAIGVA GLVTPWNFPT NQTSLKLAAA FAAGSPVVLK PSEETPFAAI 

       190        200        210        220        230        240 
ILAEIFDKVG VPKGVFNLVN GDGSGVGNPL SEHPKVRMMS FTGSGPTGSK IMEKAAKDFK 

       250        260        270        280        290        300 
KVSLELGGKS PYIVLDDVDV EEAANATTKK VVNNTGQVCT AGTRVLIPES IKEDYLTAVK 

       310        320        330        340        350        360 
EAFSKVKVGQ PREEGTQVGP IISKKQFDQV QDYIDKGINE GAELFYGGPG KPEGLDKGYF 

       370        380        390        400        410        420 
ARPTIFINVD NHMTIAQEEI FGPVMSVITY NNLDEAIEIA NDTKYGLAGY VIGKDKDTLR 

       430        440        450        460        470 
HVARSIEAGT IEINEAGRKP DLPFGGYKES GLGREWGDYG IEEFLEVKSI AGYFK

« Hide

References

[1]"Insights on evolution of virulence and resistance from the complete genome analysis of an early methicillin-resistant Staphylococcus aureus strain and a biofilm-producing methicillin-resistant Staphylococcus epidermidis strain."
Gill S.R., Fouts D.E., Archer G.L., Mongodin E.F., DeBoy R.T., Ravel J., Paulsen I.T., Kolonay J.F., Brinkac L.M., Beanan M.J., Dodson R.J., Daugherty S.C., Madupu R., Angiuoli S.V., Durkin A.S., Haft D.H., Vamathevan J.J., Khouri H. expand/collapse author list , Utterback T.R., Lee C., Dimitrov G., Jiang L., Qin H., Weidman J., Tran K., Kang K.H., Hance I.R., Nelson K.E., Fraser C.M.
J. Bacteriol. 187:2426-2438(2005) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 35984 / RP62A.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000029 Genomic DNA. Translation: AAW55043.1.
RefSeqYP_189293.1. NC_002976.3.

3D structure databases

HSSPHSSP built from PDB template 1ZUM based on UniProtKB P05091.
ProteinModelPortalQ5HMA0.
ModBaseSearch...

Protein-protein interaction databases

STRING176279.SERP1729.

Proteomic databases

PRIDEQ5HMA0.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAW55043; AAW55043; SERP1729.
GeneID3242710.
KEGGser:SERP1729.
PATRIC19614379. VBIStaEpi130894_1688.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG1012.
HOGENOMHOG000271505.
KOK00128.
OMAIKSIAGY.
ProtClustDBCLSK885774.

Enzyme and pathway databases

BioCycSEPI176279:GJJB-1798-MONOMER.

Family and domain databases

Gene3D3.40.309.10. 1 hit.
3.40.605.10. 1 hit.
InterProIPR016161. Ald_DH/histidinol_DH.
IPR016163. Ald_DH_C.
IPR016160. Ald_DH_CS.
IPR016162. Ald_DH_N.
IPR015590. Aldehyde_DH_dom.
[Graphical view]
PfamPF00171. Aldedh. 1 hit.
[Graphical view]
SUPFAMSSF53720. Aldehyde_DH/Histidinol_DH. 1 hit.
PROSITEPS00070. ALDEHYDE_DEHYDR_CYS. 1 hit.
PS00687. ALDEHYDE_DEHYDR_GLU. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameALD1_STAEQ
AccessionPrimary (citable) accession number: Q5HMA0
Entry history
Integrated into UniProtKB/Swiss-Prot: July 10, 2007
Last sequence update: February 15, 2005
Last modified: May 1, 2013
This is version 57 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·Documents