Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Q5HMA0

- ALD1_STAEQ

UniProt

Q5HMA0 - ALD1_STAEQ

Protein

Putative aldehyde dehydrogenase SERP1729

Gene

SERP1729

Organism
Staphylococcus epidermidis (strain ATCC 35984 / RP62A)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
    • BLAST
    • Align
    • Format
    • Add to basket
    • History
      Entry version 63 (01 Oct 2014)
      Sequence version 1 (15 Feb 2005)
      Previous versions | rss
    • Help video
    • Feedback
    • Comment

    Functioni

    Catalytic activityi

    An aldehyde + NAD+ + H2O = a carboxylate + NADH.

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei245 – 2451By similarity
    Active sitei279 – 2791By similarity

    Regions

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Nucleotide bindingi201 – 2077NADBy similarity

    GO - Molecular functioni

    1. aldehyde dehydrogenase (NAD) activity Source: UniProtKB-EC

    Keywords - Molecular functioni

    Oxidoreductase

    Keywords - Ligandi

    NAD

    Enzyme and pathway databases

    BioCyciSEPI176279:GJJB-1798-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Putative aldehyde dehydrogenase SERP1729 (EC:1.2.1.3)
    Gene namesi
    Ordered Locus Names:SERP1729
    OrganismiStaphylococcus epidermidis (strain ATCC 35984 / RP62A)
    Taxonomic identifieri176279 [NCBI]
    Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesStaphylococcus
    ProteomesiUP000000531: Chromosome

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 475475Putative aldehyde dehydrogenase SERP1729PRO_0000293562Add
    BLAST

    Proteomic databases

    PRIDEiQ5HMA0.

    Interactioni

    Protein-protein interaction databases

    STRINGi176279.SERP1729.

    Structurei

    3D structure databases

    ProteinModelPortaliQ5HMA0.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the aldehyde dehydrogenase family.Curated

    Phylogenomic databases

    eggNOGiCOG1012.
    HOGENOMiHOG000271505.
    KOiK00128.
    OMAiIDENRAA.
    OrthoDBiEOG6BS8QW.

    Family and domain databases

    Gene3Di3.40.309.10. 1 hit.
    3.40.605.10. 1 hit.
    InterProiIPR016161. Ald_DH/histidinol_DH.
    IPR016163. Ald_DH_C.
    IPR016160. Ald_DH_CS_CYS.
    IPR029510. Ald_DH_CS_GLU.
    IPR016162. Ald_DH_N.
    IPR015590. Aldehyde_DH_dom.
    [Graphical view]
    PfamiPF00171. Aldedh. 1 hit.
    [Graphical view]
    SUPFAMiSSF53720. SSF53720. 1 hit.
    PROSITEiPS00070. ALDEHYDE_DEHYDR_CYS. 1 hit.
    PS00687. ALDEHYDE_DEHYDR_GLU. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q5HMA0-1 [UniParc]FASTAAdd to Basket

    « Hide

    MRNFTKQYIN GEWVDSASGE TIDVINPATE EVMGKIAKGN EEDVNKAVDA    50
    ADKVYLEFRH SSVEERRELL DKIVKEYQNR KNDLIEAITD ELGAPLSVSE 100
    NVHYQMGLNH FTAARDALDS FQFEEQRGDD LVVKEAIGVA GLVTPWNFPT 150
    NQTSLKLAAA FAAGSPVVLK PSEETPFAAI ILAEIFDKVG VPKGVFNLVN 200
    GDGSGVGNPL SEHPKVRMMS FTGSGPTGSK IMEKAAKDFK KVSLELGGKS 250
    PYIVLDDVDV EEAANATTKK VVNNTGQVCT AGTRVLIPES IKEDYLTAVK 300
    EAFSKVKVGQ PREEGTQVGP IISKKQFDQV QDYIDKGINE GAELFYGGPG 350
    KPEGLDKGYF ARPTIFINVD NHMTIAQEEI FGPVMSVITY NNLDEAIEIA 400
    NDTKYGLAGY VIGKDKDTLR HVARSIEAGT IEINEAGRKP DLPFGGYKES 450
    GLGREWGDYG IEEFLEVKSI AGYFK 475
    Length:475
    Mass (Da):51,890
    Last modified:February 15, 2005 - v1
    Checksum:i905E024191EE75D1
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000029 Genomic DNA. Translation: AAW55043.1.
    RefSeqiYP_189293.1. NC_002976.3.

    Genome annotation databases

    EnsemblBacteriaiAAW55043; AAW55043; SERP1729.
    GeneIDi3242710.
    KEGGiser:SERP1729.
    PATRICi19614379. VBIStaEpi130894_1688.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000029 Genomic DNA. Translation: AAW55043.1 .
    RefSeqi YP_189293.1. NC_002976.3.

    3D structure databases

    ProteinModelPortali Q5HMA0.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 176279.SERP1729.

    Proteomic databases

    PRIDEi Q5HMA0.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AAW55043 ; AAW55043 ; SERP1729 .
    GeneIDi 3242710.
    KEGGi ser:SERP1729.
    PATRICi 19614379. VBIStaEpi130894_1688.

    Phylogenomic databases

    eggNOGi COG1012.
    HOGENOMi HOG000271505.
    KOi K00128.
    OMAi IDENRAA.
    OrthoDBi EOG6BS8QW.

    Enzyme and pathway databases

    BioCyci SEPI176279:GJJB-1798-MONOMER.

    Family and domain databases

    Gene3Di 3.40.309.10. 1 hit.
    3.40.605.10. 1 hit.
    InterProi IPR016161. Ald_DH/histidinol_DH.
    IPR016163. Ald_DH_C.
    IPR016160. Ald_DH_CS_CYS.
    IPR029510. Ald_DH_CS_GLU.
    IPR016162. Ald_DH_N.
    IPR015590. Aldehyde_DH_dom.
    [Graphical view ]
    Pfami PF00171. Aldedh. 1 hit.
    [Graphical view ]
    SUPFAMi SSF53720. SSF53720. 1 hit.
    PROSITEi PS00070. ALDEHYDE_DEHYDR_CYS. 1 hit.
    PS00687. ALDEHYDE_DEHYDR_GLU. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Insights on evolution of virulence and resistance from the complete genome analysis of an early methicillin-resistant Staphylococcus aureus strain and a biofilm-producing methicillin-resistant Staphylococcus epidermidis strain."
      Gill S.R., Fouts D.E., Archer G.L., Mongodin E.F., DeBoy R.T., Ravel J., Paulsen I.T., Kolonay J.F., Brinkac L.M., Beanan M.J., Dodson R.J., Daugherty S.C., Madupu R., Angiuoli S.V., Durkin A.S., Haft D.H., Vamathevan J.J., Khouri H.
      , Utterback T.R., Lee C., Dimitrov G., Jiang L., Qin H., Weidman J., Tran K., Kang K.H., Hance I.R., Nelson K.E., Fraser C.M.
      J. Bacteriol. 187:2426-2438(2005) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 35984 / RP62A.

    Entry informationi

    Entry nameiALD1_STAEQ
    AccessioniPrimary (citable) accession number: Q5HMA0
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: July 10, 2007
    Last sequence update: February 15, 2005
    Last modified: October 1, 2014
    This is version 63 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3