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Protein

Galactose-6-phosphate isomerase subunit LacB

Gene

lacB

Organism
Staphylococcus epidermidis (strain ATCC 35984 / RP62A)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

D-galactose 6-phosphate = D-tagatose 6-phosphate.UniRule annotation

Pathwayi: D-galactose 6-phosphate degradation

This protein is involved in step 1 of the subpathway that synthesizes D-tagatose 6-phosphate from D-galactose 6-phosphate.UniRule annotation
Proteins known to be involved in this subpathway in this organism are:
  1. Galactose-6-phosphate isomerase subunit LacB (lacB), Galactose-6-phosphate isomerase subunit LacA (lacA)
This subpathway is part of the pathway D-galactose 6-phosphate degradation, which is itself part of Carbohydrate metabolism.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes D-tagatose 6-phosphate from D-galactose 6-phosphate, the pathway D-galactose 6-phosphate degradation and in Carbohydrate metabolism.

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionIsomerase
Biological processLactose metabolism

Enzyme and pathway databases

UniPathwayiUPA00702; UER00714

Names & Taxonomyi

Protein namesi
Recommended name:
Galactose-6-phosphate isomerase subunit LacBUniRule annotation (EC:5.3.1.26UniRule annotation)
Gene namesi
Name:lacBUniRule annotation
Ordered Locus Names:SERP1794
OrganismiStaphylococcus epidermidis (strain ATCC 35984 / RP62A)
Taxonomic identifieri176279 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesStaphylococcaceaeStaphylococcus
Proteomesi
  • UP000000531 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002081441 – 171Galactose-6-phosphate isomerase subunit LacBAdd BLAST171

Interactioni

Subunit structurei

Heteromultimeric protein consisting of LacA and LacB.UniRule annotation

Protein-protein interaction databases

STRINGi176279.SERP1794

Structurei

3D structure databases

ProteinModelPortaliQ5HM36
SMRiQ5HM36
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the LacAB/RpiB family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0698 LUCA
HOGENOMiHOG000226301
KOiK01819
OMAiTYSAHQG

Family and domain databases

Gene3Di3.40.1400.10, 1 hit
HAMAPiMF_01556 LacB, 1 hit
InterProiView protein in InterPro
IPR004784 LacB
IPR003500 RpiB_LacA_LacB
IPR036569 RpiB_LacA_LacB_sf
PANTHERiPTHR30345 PTHR30345, 1 hit
PfamiView protein in Pfam
PF02502 LacAB_rpiB, 1 hit
PIRSFiPIRSF005384 RpiB_LacA_B, 1 hit
SUPFAMiSSF89623 SSF89623, 1 hit
TIGRFAMsiTIGR01119 lacB, 1 hit
TIGR00689 rpiB_lacA_lacB, 1 hit

Sequencei

Sequence statusi: Complete.

Q5HM36-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKIAIGCDHI VTDTKMEVSQ HLKSQGHEVI DVGTYDFTRT HYPIYGKKVG
60 70 80 90 100
EKVASGEADL GVCICGTGVG ISNAANKVPG VRTALVRDMT SALYSKEELN
110 120 130 140 150
ANVVSFGGKV AGELFIFDIV DAFIEAEYKP TEENKKLIAK INHLEAHNND
160 170
QADPHFFDEF LEKWNKGEYH D
Length:171
Mass (Da):18,903
Last modified:February 15, 2005 - v1
Checksum:i0CF3B0A59420B477
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000029 Genomic DNA Translation: AAW55179.1
RefSeqiWP_001829777.1, NC_002976.3

Genome annotation databases

EnsemblBacteriaiAAW55179; AAW55179; SERP1794
KEGGiser:SERP1794

Similar proteinsi

Entry informationi

Entry nameiLACB_STAEQ
AccessioniPrimary (citable) accession number: Q5HM36
Entry historyiIntegrated into UniProtKB/Swiss-Prot: December 20, 2005
Last sequence update: February 15, 2005
Last modified: May 23, 2018
This is version 75 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

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