Reviewed, UniProtKB/Swiss-Prot Q5HLQ6 (ARAB_STAEQ)

Names and origin

Protein names

Recommended name:
    Ribulokinase
    EC=2.7.1.16

Gene names

Name:	araB
Ordered Locus Names:	SERP1927

Organism

Staphylococcus epidermidis (strain ATCC 35984 / RP62A) [Complete proteome] [HAMAP]

Taxonomic identifier

176279 [NCBI]

Taxonomic lineage

Bacteria › Firmicutes › Bacillales › Staphylococcus

Protein attributes

Sequence length	536 AA.
Sequence status	Complete.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	ATP + L(or D)-ribulose = ADP + L(or D)-ribulose 5-phosphate. HAMAP MF_00520
Pathway	Carbohydrate degradation; L-arabinose degradation via L-ribulose; D-xylulose 5-phosphate from L-arabinose (bacterial route): step 2/3. HAMAP MF_00520
Sequence similarities	Belongs to the ribulokinase family.

Ontologies

Keywords
Biological process	Arabinose catabolism Carbohydrate metabolism
Ligand	ATP-binding Nucleotide-binding
Molecular function	Kinase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	L-arabinose catabolic process Inferred from electronic annotation. Source: HAMAP
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW ribulokinase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 536	536	Ribulokinase HAMAP MF_00520		PRO_0000198373

Sequences

	Sequence		Length	Mass (Da)
	Q5HLQ6-1 [UniParc]. Last modified February 15, 2005. Version 1. Checksum: 30C27F7C381AF443	FASTA	536	60,092
	10 20 30 40 50 60 MSYSIGIDFG TASGRVILAD TSNGHIISRY EEDYANGTYM NSLYDKPLPE NYFLQNADDY 70 80 90 100 110 120 LQILEQGVQF VLEDSKVNKN DVVGIGVDFT SSTIIFLDEQ FEPLHRHEDL KTNPHAYVKL 130 140 150 160 170 180 WKHHGAQDEA NYMIQMSKNK NWLDYYGSSV NSEWMIPKIL EVKHEAPEIL RRARYIMEAG 190 200 210 220 230 240 DYITSILTNS NIRSNCGIGF KGFWDNEAGF NYDFFHSVDP DLPKIVKEKC EAPIISIGES 250 260 270 280 290 300 AGRLCKDYQQ IWGLSQDVQV SPFIIDAHSG VLGVGAIEAG EFTAVIGTST CHLMLDSRQV 310 320 330 340 350 360 PISSITGSVK NAIIPGLYAY EAGQPAVGDL FEYSKNQAPK HIVDQANEHH MHVLNYLEEL 370 380 390 400 410 420 ASHIRIEEQH VVVLDWLNGN RSILSNSHLT GSIFGLTLQT PYEMIHRAYI EATAFGTKLI 430 440 450 460 470 480 MKQFEDNHIP VHTVYASGGI PQKSKLLVEI YANVLNKRVV VIDSSNASAL GAAMLGANVG 490 500 510 520 530 NAYSTLKEAA LSMKQPIAYI QEPEIQKVQA YKPLYHKYCE LHDLLGRQYP ELSYLI

References

[1]

"Insights on evolution of virulence and resistance from the complete genome analysis of an early methicillin-resistant Staphylococcus aureus strain and a biofilm-producing methicillin-resistant Staphylococcus epidermidis strain." Gill S.R., Fouts D.E., Archer G.L., Mongodin E.F., DeBoy R.T., Ravel J., Paulsen I.T., Kolonay J.F., Brinkac L.M., Beanan M.J., Dodson R.J., Daugherty S.C., Madupu R., Angiuoli S.V., Durkin A.S., Haft D.H., Vamathevan J.J., Khouri H. , Utterback T.R., Lee C., Dimitrov G., Jiang L., Qin H., Weidman J., Tran K., Kang K.H., Hance I.R., Nelson K.E., Fraser C.M. J. Bacteriol. 187:2426-2438(2005) [PubMed: 15774886] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000029 Genomic DNA. Translation: AAW55269.1.
RefSeq	YP_189487.1.
3D structure databases
SMR	Q5HLQ6. Positions 5-525.
ModBase	Search...
Protein-protein interaction databases
STRING	Q5HLQ6.
Genome annotation databases
GeneID	3241894.
GenomeReviews	Gene locus SERP1927 in contig CP000029_GR.
KEGG	ser:SERP1927.
NMPDR	fig|176279.3.peg.2245.
TIGR	SERP1927.
Phylogenomic databases
eggNOG	COG1069.
HOGENOM	HBG312681.
OMA	IMEAGDY.
Enzyme and pathway databases
BioCyc	SEPI176279:SERP1927-MONOMER.
Family and domain databases
HAMAP	MF_00520. Ribulokinase. [Tree]
InterPro	IPR000577. Carb_kinase_FGGY. IPR018485. Carb_kinase_FGGY_C. IPR018484. Carb_kinase_FGGY_N. IPR005929. L_ribulokin. [Graphical view]
PANTHER	PTHR10196. FGGY_kin. 1 hit.
Pfam	PF02782. FGGY_C. 1 hit. PF00370. FGGY_N. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

ARAB_STAEQ

Accession

Primary (citable) accession number: Q5HLQ6

Entry history

Integrated into UniProtKB/Swiss-Prot:	November 22, 2005
Last sequence update:	February 15, 2005
Last modified:	January 19, 2010
This is version 32 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)