Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

Q5HLN6

- Q5HLN6_STAEQ

UniProt

Q5HLN6 - Q5HLN6_STAEQ

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein
Submitted name:

Transcriptional regulator TcaR

Gene

tcaR

Organism
Staphylococcus epidermidis (strain ATCC 35984 / RP62A)
Status
Unreviewed - Annotation score: 1 out of 5- Experimental evidence at protein leveli

Functioni

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei101 – 1011Cacodylate 2Imported

GO - Molecular functioni

  1. sequence-specific DNA binding transcription factor activity Source: InterPro
Complete GO annotation...

Enzyme and pathway databases

BioCyciSEPI176279:GJJB-2026-MONOMER.

Names & Taxonomyi

Protein namesi
Submitted name:
Transcriptional regulator TcaRImported
Gene namesi
Name:tcaRImported
Ordered Locus Names:SERP1949Imported
OrganismiStaphylococcus epidermidis (strain ATCC 35984 / RP62A)Imported
Taxonomic identifieri176279 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesStaphylococcus
ProteomesiUP000000531: Chromosome

Subcellular locationi

GO - Cellular componenti

  1. intracellular Source: InterPro
Complete GO annotation...

Interactioni

Protein-protein interaction databases

DIPiDIP-59325N.
STRINGi176279.SERP1949.

Structurei

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
3KP2X-ray2.55A/B1-151[»]
3KP3X-ray3.20A/B1-151[»]
3KP4X-ray2.84A/B1-151[»]
3KP5X-ray3.00A/B1-151[»]
3KP6X-ray2.45A/B1-151[»]
3KP7X-ray2.30A/B1-151[»]
4EJTX-ray3.00A/B1-151[»]
4EJUX-ray2.40A/B1-151[»]
4EJVX-ray2.90A/B1-151[»]
4EJWX-ray2.80A/B1-151[»]
ProteinModelPortaliQ5HLN6.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiQ5HLN6.

Family & Domainsi

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni37 – 404Cacodylate 1 bindingImported
Regioni70 – 745Cacodylate 1 bindingImported

Phylogenomic databases

eggNOGiNOG85258.
HOGENOMiHOG000280237.
OMAiMKQFIDD.
OrthoDBiEOG6091DT.

Family and domain databases

Gene3Di1.10.10.10. 1 hit.
InterProiIPR000835. HTH_MarR-typ.
IPR011991. WHTH_DNA-bd_dom.
[Graphical view]
SMARTiSM00347. HTH_MARR. 1 hit.
[Graphical view]
PROSITEiPS50995. HTH_MARR_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q5HLN6-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MVRRIEDHIS FLEKFINDVN TLTAKLLKDL QTEYGISAEQ SHVLNMLSIE
60 70 80 90 100
ALTVGQITEK QGVNKAAVSR RVKKLLNAEL VKLEKPDSNT DQRLKIIKLS
110 120 130 140 150
NKGKKYIKER KAIMSHIASD MTSDFDSKEI EKVRQVLEII DYRIQSYTSK

L
Length:151
Mass (Da):17,348
Last modified:February 15, 2005 - v1
Checksum:i600536DFEFD5399D
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000029 Genomic DNA. Translation: AAW52831.1.
RefSeqiYP_189507.1. NC_002976.3.

Genome annotation databases

EnsemblBacteriaiAAW52831; AAW52831; SERP1949.
GeneIDi3242456.
KEGGiser:SERP1949.
PATRICi19614818. VBIStaEpi130894_1898.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000029 Genomic DNA. Translation: AAW52831.1 .
RefSeqi YP_189507.1. NC_002976.3.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
Entry Method Resolution (Å) Chain Positions PDBsum
3KP2 X-ray 2.55 A/B 1-151 [» ]
3KP3 X-ray 3.20 A/B 1-151 [» ]
3KP4 X-ray 2.84 A/B 1-151 [» ]
3KP5 X-ray 3.00 A/B 1-151 [» ]
3KP6 X-ray 2.45 A/B 1-151 [» ]
3KP7 X-ray 2.30 A/B 1-151 [» ]
4EJT X-ray 3.00 A/B 1-151 [» ]
4EJU X-ray 2.40 A/B 1-151 [» ]
4EJV X-ray 2.90 A/B 1-151 [» ]
4EJW X-ray 2.80 A/B 1-151 [» ]
ProteinModelPortali Q5HLN6.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

DIPi DIP-59325N.
STRINGi 176279.SERP1949.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAW52831 ; AAW52831 ; SERP1949 .
GeneIDi 3242456.
KEGGi ser:SERP1949.
PATRICi 19614818. VBIStaEpi130894_1898.

Phylogenomic databases

eggNOGi NOG85258.
HOGENOMi HOG000280237.
OMAi MKQFIDD.
OrthoDBi EOG6091DT.

Enzyme and pathway databases

BioCyci SEPI176279:GJJB-2026-MONOMER.

Miscellaneous databases

EvolutionaryTracei Q5HLN6.

Family and domain databases

Gene3Di 1.10.10.10. 1 hit.
InterProi IPR000835. HTH_MarR-typ.
IPR011991. WHTH_DNA-bd_dom.
[Graphical view ]
SMARTi SM00347. HTH_MARR. 1 hit.
[Graphical view ]
PROSITEi PS50995. HTH_MARR_2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Insights on evolution of virulence and resistance from the complete genome analysis of an early methicillin-resistant Staphylococcus aureus strain and a biofilm-producing methicillin-resistant Staphylococcus epidermidis strain."
    Gill S.R., Fouts D.E., Archer G.L., Mongodin E.F., DeBoy R.T., Ravel J., Paulsen I.T., Kolonay J.F., Brinkac L.M., Beanan M.J., Dodson R.J., Daugherty S.C., Madupu R., Angiuoli S.V., Durkin A.S., Haft D.H., Vamathevan J.J., Khouri H.
    , Utterback T.R., Lee C., Dimitrov G., Jiang L., Qin H., Weidman J., Tran K., Kang K.H., Hance I.R., Nelson K.E., Fraser C.M.
    J. Bacteriol. 187:2426-2438(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 35984 / RP62AImported.
  2. "Structural study of TcaR and its complexes with multiple antibiotics from Staphylococcus epidermidis."
    Chang Y.M., Jeng W.Y., Ko T.P., Yeh Y.J., Chen C.K., Wang A.H.
    Proc. Natl. Acad. Sci. U.S.A. 107:8617-8622(2010) [PubMed] [Europe PMC] [Abstract]
    Cited for: X-RAY CRYSTALLOGRAPHY (2.30 ANGSTROMS).
  3. "Functional studies of ssDNA binding ability of MarR family protein TcaR from Staphylococcus epidermidis."
    Chang Y.M., Chen C.K., Chang Y.C., Jeng W.Y., Hou M.H., Wang A.H.
    PLoS ONE 7:e45665-e45665(2012) [PubMed] [Europe PMC] [Abstract]
    Cited for: X-RAY CRYSTALLOGRAPHY (3.00 ANGSTROMS).

Entry informationi

Entry nameiQ5HLN6_STAEQ
AccessioniPrimary (citable) accession number: Q5HLN6
Entry historyi
Integrated into UniProtKB/TrEMBL: February 15, 2005
Last sequence update: February 15, 2005
Last modified: November 26, 2014
This is version 71 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

3D-structureImported, Complete proteome, Reference proteomeImported

External Data

Dasty 3