Reviewed, UniProtKB/Swiss-Prot Q5HLN0 (MQO1_STAEQ)

Names and origin

Protein names

Recommended name:
    Probable malate:quinone oxidoreductase 1
    EC=1.1.99.16
Alternative name(s):
    Malate dehydrogenase [acceptor] 1
    MQO 1

Gene names

Name:	mqo1
Ordered Locus Names:	SERP1955

Organism

Staphylococcus epidermidis (strain ATCC 35984 / RP62A) [Complete proteome] [HAMAP]

Taxonomic identifier

176279 [NCBI]

Taxonomic lineage

Bacteria › Firmicutes › Bacillales › Staphylococcus

Protein attributes

Sequence length	492 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	(S)-malate + acceptor = oxaloacetate + reduced acceptor. HAMAP MF_00212
Cofactor	FAD By similarity.
Pathway	Carbohydrate metabolism; tricarboxylic acid cycle. HAMAP MF_00212
Sequence similarities	Belongs to the MQO family.

Ontologies

Keywords
Biological process	Tricarboxylic acid cycle
Ligand	FAD Flavoprotein
Molecular function	Oxidoreductase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	oxidation reduction Inferred from electronic annotation. Source: UniProtKB-KW tricarboxylic acid cycle Inferred from electronic annotation. Source: HAMAP
Molecular function	malate dehydrogenase (acceptor) activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 492	492	Probable malate:quinone oxidoreductase 1 HAMAP MF_00212		PRO_0000128753

Sequences

	Sequence		Length	Mass (Da)
	Q5HLN0-1 [UniParc]. Last modified February 15, 2005. Version 1. Checksum: A0791686F3969AD3	FASTA	492	55,032
	10 20 30 40 50 60 MNTQHSKTDV ILIGGGIMSA TLGTLLKELT PEKDIQLFER LSQPGEESSN VWNNAGTGHS 70 80 90 100 110 120 ALCELNYTKE GKDGSVDITK AIHINEQFQI SKQFWAYLIR EGHIESPDKF IQSVPHMSFV 130 140 150 160 170 180 KGEENVKFLK SRVASLQKNV LFEKMKISQD PEKINSWVPL MMEGRQSDEA IAITYDETGT 190 200 210 220 230 240 DVNFGALTKK LIANLQQKNV GINYKHEVLD IKKLNNGNWQ VVVKDLNTSN VMNYESKFVF 250 260 270 280 290 300 IGAGGASLPL LQKTKIKESK HIGGFPVSGL FLRCKNPDVI HRHHAKVYGK AEVGAPPMSV 310 320 330 340 350 360 PHLDTRFVNG EKSLLFGPFA GFSPKFLKNG SYLDLVKSVK PNNMITMLSA GVKEFNLTKY 370 380 390 400 410 420 LVSQLMLSNE ERINDLRVFL PEAKDEDWEV ITAGQRVQVI KDTDKSKGQL QFGTEVITSE 430 440 450 460 470 480 DGSLAALLGA SPGASTAVDI MFDVLQRCYK SEFKSWEPKI KEMVPSFGLK LSEHEDMYHS 490 INEEVKKYLN VK

References

[1]

"Insights on evolution of virulence and resistance from the complete genome analysis of an early methicillin-resistant Staphylococcus aureus strain and a biofilm-producing methicillin-resistant Staphylococcus epidermidis strain." Gill S.R., Fouts D.E., Archer G.L., Mongodin E.F., DeBoy R.T., Ravel J., Paulsen I.T., Kolonay J.F., Brinkac L.M., Beanan M.J., Dodson R.J., Daugherty S.C., Madupu R., Angiuoli S.V., Durkin A.S., Haft D.H., Vamathevan J.J., Khouri H. , Utterback T.R., Lee C., Dimitrov G., Jiang L., Qin H., Weidman J., Tran K., Kang K.H., Hance I.R., Nelson K.E., Fraser C.M. J. Bacteriol. 187:2426-2438(2005) [PubMed: 15774886] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	CP000029 Genomic DNA. Translation: AAW52837.1.
RefSeq	YP_189513.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	3242574.
GenomeReviews	Gene locus SERP1955 in contig CP000029_GR.
KEGG	ser:SERP1955.
NMPDR	fig|176279.3.peg.2324.
TIGR	SERP1955.
Phylogenomic databases
HOGENOM	Q5HLN0.
OMA	Q5HLN0. HLAKAYG.
Enzyme and pathway databases
BioCyc	SEPI176279:SERP1955-MON.
Family and domain databases
HAMAP	MF_00212. [Tree]
InterPro	IPR006231. Malate_quinone_OxRdtase. [Graphical view]
Pfam	PF06039. Mqo. 1 hit. [Graphical view]
TIGRFAMs	TIGR01320. mal_quin_oxido. 1 hit.
ProtoNet	Search...

Entry information

Entry name

MQO1_STAEQ

Accession

Primary (citable) accession number: Q5HLN0

Entry history

Integrated into UniProtKB/Swiss-Prot:	July 19, 2005
Last sequence update:	February 15, 2005
Last modified:	June 16, 2009
This is version 25 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)