SubmitCancel

Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

Q5HLA3

- ALDA_STAEQ

UniProt

Q5HLA3 - ALDA_STAEQ

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein
Putative aldehyde dehydrogenase AldA
Gene
aldA, SERP2084
Organism
Staphylococcus epidermidis (strain ATCC 35984 / RP62A)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

An aldehyde + NAD+ + H2O = a carboxylate + NADH.

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei257 – 2571 By similarity
Active sitei291 – 2911 By similarity

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi213 – 2197NAD By similarity

GO - Molecular functioni

  1. aldehyde dehydrogenase (NAD) activity Source: UniProtKB-EC
Complete GO annotation...

GO - Biological processi

    Complete GO annotation...

    Keywords - Molecular functioni

    Oxidoreductase

    Keywords - Ligandi

    NAD

    Enzyme and pathway databases

    BioCyciSEPI176279:GJJB-2161-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Putative aldehyde dehydrogenase AldA (EC:1.2.1.3)
    Gene namesi
    Name:aldA
    Ordered Locus Names:SERP2084
    OrganismiStaphylococcus epidermidis (strain ATCC 35984 / RP62A)
    Taxonomic identifieri176279 [NCBI]
    Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesStaphylococcus
    ProteomesiUP000000531: Chromosome

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 497497Putative aldehyde dehydrogenase AldA
    PRO_0000056462Add
    BLAST

    Interactioni

    Protein-protein interaction databases

    STRINGi176279.SERP2084.

    Structurei

    3D structure databases

    ProteinModelPortaliQ5HLA3.

    Family & Domainsi

    Sequence similaritiesi

    Phylogenomic databases

    eggNOGiCOG1012.
    HOGENOMiHOG000271505.
    KOiK00128.
    OMAiMACWKMA.
    OrthoDBiEOG6BS8QW.

    Family and domain databases

    Gene3Di3.40.309.10. 1 hit.
    3.40.605.10. 1 hit.
    InterProiIPR016161. Ald_DH/histidinol_DH.
    IPR016163. Ald_DH_C.
    IPR016160. Ald_DH_CS_CYS.
    IPR029510. Ald_DH_CS_GLU.
    IPR016162. Ald_DH_N.
    IPR015590. Aldehyde_DH_dom.
    [Graphical view]
    PfamiPF00171. Aldedh. 1 hit.
    [Graphical view]
    SUPFAMiSSF53720. SSF53720. 1 hit.
    PROSITEiPS00070. ALDEHYDE_DEHYDR_CYS. 1 hit.
    PS00687. ALDEHYDE_DEHYDR_GLU. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q5HLA3-1 [UniParc]FASTAAdd to Basket

    « Hide

    MTNINVRNYI DESYGLFINN EFQASDSGET LTVSNPANGE DLAKVARAGK    50
    KDVDKAVQAA HDAFDSWSKI SKEERADYLL EISRRIHEKT EHLATVESLQ 100
    NGKPYRETST IDVPQAANQF KYFASVLTTD EGSVNEIDQN TMSLVVNEPV 150
    GVVGAVVAWN FPILLASWKL GPALAAGNTV VIQPSSSTPL SLIELAKIFQ 200
    EVLPKGVVNV LTGKGSESGD AIFHHEGVDK LSFTGSTDVG YGVAQAGAER 250
    IVPTTLELGG KSANIIFDDA NLEQVIEGVQ LGILFNQGEV CSAGSRLLVQ 300
    SSIYDELLPK LKEAFENIKV GDPFDEDTKM SAQTGPEQLD KIESYIKIAE 350
    EDDKANILTG GHRITDNGLD KGYFFEPTII EINDNKHQLA QEEIFGPVVV 400
    VEKFDDEQEA IEIANDSEYG LAGGIFTTDI HRALNVAKAM RTGRIWINTY 450
    NQIPAGAPFG GYKKSGIGRE VYKDAIKNYQ QVKNIFIDTS NQTKGLY 497
    Length:497
    Mass (Da):54,247
    Last modified:February 15, 2005 - v1
    Checksum:iDDCD2D2E0F2FDA7E
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000029 Genomic DNA. Translation: AAW52930.1.
    RefSeqiYP_189640.1. NC_002976.3.

    Genome annotation databases

    EnsemblBacteriaiAAW52930; AAW52930; SERP2084.
    GeneIDi3242375.
    KEGGiser:SERP2084.
    PATRICi19615080. VBIStaEpi130894_2029.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000029 Genomic DNA. Translation: AAW52930.1 .
    RefSeqi YP_189640.1. NC_002976.3.

    3D structure databases

    ProteinModelPortali Q5HLA3.
    ModBasei Search...

    Protein-protein interaction databases

    STRINGi 176279.SERP2084.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AAW52930 ; AAW52930 ; SERP2084 .
    GeneIDi 3242375.
    KEGGi ser:SERP2084.
    PATRICi 19615080. VBIStaEpi130894_2029.

    Phylogenomic databases

    eggNOGi COG1012.
    HOGENOMi HOG000271505.
    KOi K00128.
    OMAi MACWKMA.
    OrthoDBi EOG6BS8QW.

    Enzyme and pathway databases

    BioCyci SEPI176279:GJJB-2161-MONOMER.

    Family and domain databases

    Gene3Di 3.40.309.10. 1 hit.
    3.40.605.10. 1 hit.
    InterProi IPR016161. Ald_DH/histidinol_DH.
    IPR016163. Ald_DH_C.
    IPR016160. Ald_DH_CS_CYS.
    IPR029510. Ald_DH_CS_GLU.
    IPR016162. Ald_DH_N.
    IPR015590. Aldehyde_DH_dom.
    [Graphical view ]
    Pfami PF00171. Aldedh. 1 hit.
    [Graphical view ]
    SUPFAMi SSF53720. SSF53720. 1 hit.
    PROSITEi PS00070. ALDEHYDE_DEHYDR_CYS. 1 hit.
    PS00687. ALDEHYDE_DEHYDR_GLU. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Insights on evolution of virulence and resistance from the complete genome analysis of an early methicillin-resistant Staphylococcus aureus strain and a biofilm-producing methicillin-resistant Staphylococcus epidermidis strain."
      Gill S.R., Fouts D.E., Archer G.L., Mongodin E.F., DeBoy R.T., Ravel J., Paulsen I.T., Kolonay J.F., Brinkac L.M., Beanan M.J., Dodson R.J., Daugherty S.C., Madupu R., Angiuoli S.V., Durkin A.S., Haft D.H., Vamathevan J.J., Khouri H.
      , Utterback T.R., Lee C., Dimitrov G., Jiang L., Qin H., Weidman J., Tran K., Kang K.H., Hance I.R., Nelson K.E., Fraser C.M.
      J. Bacteriol. 187:2426-2438(2005) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 35984 / RP62A.

    Entry informationi

    Entry nameiALDA_STAEQ
    AccessioniPrimary (citable) accession number: Q5HLA3
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: November 22, 2005
    Last sequence update: February 15, 2005
    Last modified: June 11, 2014
    This is version 63 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3

    Similar proteinsi